UCSF

DNA Topoisomerase 1, Rat (1 Compounds)

Swissprot:
TOP1_RAT
Stitch:
TOP1_RAT
UniProt:
Q9WUL0
ChEMBL:
CHEMBL1075164
PDB:
Top1

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 1 1 1 0
Binding ≤ 1μM 1 1 1 0

Reactome Network (0)

UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
TOP1_HUMAN P11387 CHEMBL1781 DNA Topoisomerase I, Human 358 28 14 10
TOP1_MOUSE Q04750 CHEMBL2814 DNA Topoisomerase I, Mouse 29 1 2 1

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
TOP1-1-E DNA Topoisomerase 1 (cluster #1 Of 2), Eukaryotic 369 32 18 11
TOP1-2-E DNA Topoisomerase 1 (cluster #2 Of 2), Eukaryotic 1 0 0 0
Uniprot Swissprot Chembl Description Number Shared
AA1R_RAT P25099 CHEMBL318 Adenosine A1 Receptor, Rat 1
ABCG2_HUMAN Q9UNQ0 CHEMBL5393 ATP-binding Cassette Sub-family G Member 2, Human 1
ALDR_BOVIN P16116 CHEMBL3081 Aldose Reductase, Bovin 1
ALDR_RAT P07943 CHEMBL2622 Aldose Reductase, Rat 1
AOFA_HUMAN P21397 CHEMBL1951 Monoamine Oxidase A, Human 1
CCNB1_HUMAN P14635 CHEMBL2412 G2/mitotic-specific Cyclin B1, Human 1
CCNB2_HUMAN O95067 CHEMBL3723 G2/mitotic-specific Cyclin B2, Human 1
CCNB3_HUMAN Q8WWL7 CHEMBL3606 G2/mitotic-specific Cyclin B3, Human 1
CD38_HUMAN P28907 CHEMBL4660 Lymphocyte Differentiation Antigen CD38, Human 1
CDK1_HUMAN P06493 CHEMBL308 Cyclin-dependent Kinase 1, Human 1
CP1B1_HUMAN Q16678 CHEMBL4878 Cytochrome P450 1B1, Human 1
FABI_ECOLI P0AEK4 CHEMBL1857 Enoyl-[acyl-carrier-protein] Reductase, Ecoli 1
GSK3A_HUMAN P49840 CHEMBL2850 Glycogen Synthase Kinase-3 Alpha, Human 1
GSK3B_HUMAN P49841 CHEMBL262 Glycogen Synthase Kinase-3 Beta, Human 1
LGUL_HUMAN Q04760 CHEMBL2424 Glyoxalase I, Human 1
LOX1_SOYBN P08170 CHEMBL4586 Seed Lipoxygenase-1, Soybn 1
NANH_CLOPE P10481 CHEMBL5189 Sialidase, Clope 1
NOX4_HUMAN Q9NPH5 CHEMBL1250375 NADPH Oxidase 4, Human 1
Q965D5_PLAFA Q965D5 CHEMBL4150 Enoyl-acyl-carrier Protein Reductase, Plafa 1
Q965D6_PLAFA Q965D6 CHEMBL4513 3-oxoacyl-acyl-carrier Protein Reductase, Plafa 1
Q965D7_PLAFA Q965D7 CHEMBL4512 Fatty Acid Synthase, Plafa 1
XDH_BOVIN P80457 CHEMBL3649 Xanthine Dehydrogenase, Bovin 1
XDH_HUMAN P47989 CHEMBL1929 Xanthine Dehydrogenase, Human 1
Z104294 Z104294 CHEMBL1907600 Cyclin-dependent Kinase 5/CDK5 Activator 1 1