UCSF

A427 (49 Compounds)

Swissprot:
Z103204
Stitch:
Z103204
UniProt:
Z103204
ChEMBL:
CHEMBL1075389

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Functional ≤ 10μM 49 18 10 10

Reactome Network (0)

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
Z80224 Z80224 CHEMBL387 MCF7 (Breast Carcinoma Cells) 40
Z80008 Z80008 CHEMBL612565 5637 (Epithelial Bladder Carcinoma Cells) 33
Z80112 Z80112 CHEMBL614033 DAN-G 30
Z80473 Z80473 CHEMBL613527 SISO 19
Z80604 Z80604 CHEMBL612815 YAPC 19
Z50425 Z50425 CHEMBL364 Plasmodium Falciparum 7
Z80193 Z80193 CHEMBL386 L1210 (Lymphocytic Leukemia Cells) 7
Z80362 Z80362 CHEMBL389 P388 (Lymphoma Cells) 6
Z80682 Z80682 CHEMBL392 A549 (Lung Carcinoma Cells) 6
Z80928 Z80928 CHEMBL394 HCT-116 (Colon Carcinoma Cells) 6
Z50587 Z50587 CHEMBL372 Homo Sapiens 5
Z80156 Z80156 CHEMBL383 HL-60 (Promyeloblast Leukemia Cells) 5
Z80166 Z80166 CHEMBL384 HT-29 (Colon Adenocarcinoma Cells) 5
Z80186 Z80186 CHEMBL385 K562 (Erythroleukemia Cells) 5
Z80285 Z80285 CHEMBL614177 MOLT-4 (Acute T-lymphoblastic Leukemia Cells) 5
Z81115 Z81115 CHEMBL398 KB (Squamous Cell Carcinoma) 5
Z81247 Z81247 CHEMBL399 HeLa (Cervical Adenocarcinoma Cells) 5
Z80064 Z80064 CHEMBL382 CCRF-CEM (T-cell Leukemia) 4
Z80583 Z80583 CHEMBL391 Vero (Kidney Cells) 4
Z81024 Z81024 CHEMBL396 NCI-H460 (Non-small Cell Lung Carcinoma) 4
Z81252 Z81252 CHEMBL400 MDA-MB-231 (Breast Adenocarcinoma Cells) 4
Z80025 Z80025 CHEMBL614519 ACHN (Renal Adenocarcinoma Cells) 3
Z80035 Z80035 CHEMBL381 B16 (Melanoma Cells) 3
Z80125 Z80125 CHEMBL613508 DU-145 (Prostate Carcinoma) 3
Z80211 Z80211 CHEMBL614721 LoVo (Colon Adenocarcinoma Cells) 3
Z80244 Z80244 CHEMBL614335 MDA-MB-468 (Breast Adenocarcinoma) 3
Z80322 Z80322 CHEMBL614135 NCI-H358 (Lung Carcinama Cells) 3
Z80354 Z80354 CHEMBL614213 OVCAR-3 (Ovarian Adenocarcinoma Cells) 3
Z80390 Z80390 CHEMBL390 PC-3 (Prostate Carcinoma Cells) 3
Z80488 Z80488 CHEMBL614922 SK-MEL-5 (Melanoma Cells) 3
Z80526 Z80526 CHEMBL612544 SW480 (Colon Adenocarcinoma Cells) 3
Z80847 Z80847 CHEMBL612250 FaDu (Pharyngeal Carcinoma Cells) 3
Z80874 Z80874 CHEMBL393 CEM (T-cell Leukemia) 3
Z81017 Z81017 CHEMBL614647 WiDr (Colon Adenocarcinoma Cells) 3
Z81054 Z81054 CHEMBL613977 SF-268 (Glioblastoma Cells) 3
Z81065 Z81065 CHEMBL613984 IGROV-1 (Ovarian Adenocarcinoma Cells) 3
Z81335 Z81335 CHEMBL612263 HCT-15 (Colon Adenocarcinoma Cells) 3
DYR_LACCA P00381 CHEMBL2902 Dihydrofolate Reductase, Lacca 2
Z103203 Z103203 CHEMBL1075388 A375 2
Z103205 Z103205 CHEMBL1075390 A431 2
Z50185 Z50185 CHEMBL352 Staphylococcus Aureus 2
Z50186 Z50186 CHEMBL353 Staphylococcus Epidermidis 2
Z50266 Z50266 CHEMBL357 Enterococcus Faecium 2
Z50362 Z50362 CHEMBL613075 Lactobacillus Casei 2
Z50594 Z50594 CHEMBL375 Mus Musculus 2
Z80001 Z80001 CHEMBL614508 143B 2
Z80054 Z80054 CHEMBL614058 Caco-2 (Colon Adenocarcinoma Cells) 2
Z80063 Z80063 CHEMBL614027 CCRF S-180 2
Z80099 Z80099 CHEMBL614561 COLO 205 (Colon Adenocarcinoma Cells) 2
Z80164 Z80164 CHEMBL614580 HT-1080 (Fibrosarcoma Cells) 2
Z80171 Z80171 CHEMBL614582 HuTu80 2
Z80192 Z80192 CHEMBL614709 KM12 (Colon Adenocarcinoma Cells) 2
Z80214 Z80214 CHEMBL614317 M14 (Melanoma Cells) 2
Z80227 Z80227 CHEMBL614324 MCF7-ADR (Breast Carcinoma Cells) 2
Z80231 Z80231 CHEMBL614328 MCF7S (Breast Carcinoma Cells) 2
Z80356 Z80356 CHEMBL614214 OVCAR-5 (Ovarian Adenocarcinoma Cells) 2
Z80357 Z80357 CHEMBL612555 OVCAR-8 (Ovarian Adenocarcinoma Cells) 2
Z80407 Z80407 CHEMBL614383 R1 2
Z80408 Z80408 CHEMBL614384 R1-CCRF-CEM (Lymphoblastic Leukemia) 2
Z80409 Z80409 CHEMBL614385 R2 2
Z80410 Z80410 CHEMBL613523 R2-CCRF-CEM (Lymphoblastic Leukemia) 2
Z80411 Z80411 CHEMBL614143 R30dm-CCRF-CEM (Lymphoblastic Leukemia) 2
Z80433 Z80433 CHEMBL614882 RPMI-8226 (Multiple Myeloma Cells) 2
Z80435 Z80435 CHEMBL614145 RT-112 2
Z80436 Z80436 CHEMBL614884 RT-4 2
Z80443 Z80443 CHEMBL612567 S180 (Sarcoma Cells) 2
Z80455 Z80455 CHEMBL614899 SCC-15 2
Z80457 Z80457 CHEMBL614901 SCC-25 2
Z80459 Z80459 CHEMBL614147 SCC-7 2
Z80468 Z80468 CHEMBL614908 SF-295 (Glioblastoma Cells) 2
Z80482 Z80482 CHEMBL614917 SK-MEL-2 (Melanoma Cells) 2
Z80485 Z80485 CHEMBL614919 SK-MEL-28 (Melanoma Cells) 2
Z80546 Z80546 CHEMBL615013 TERT-RPE1 (Retinal Pigmented Epithelial Cells) 2
Z80560 Z80560 CHEMBL615022 U-251 (Glioma Cells) 2
Z80563 Z80563 CHEMBL615025 U-373 MG ( Glioblastoma Cells) 2
Z80565 Z80565 CHEMBL614247 U-87 MG (Glioblastoma Cells) 2
Z80568 Z80568 CHEMBL612796 UACC-257 (Melanoma Cells) 2
Z80570 Z80570 CHEMBL614610 UACC-62 (Melanoma Cells) 2
Z80575 Z80575 CHEMBL614388 UO-31 (Renal Carcinoma Cells) 2
Z80640 Z80640 CHEMBL613102 786-0 (Renal Carcinoma Cells) 2
Z80657 Z80657 CHEMBL614255 A253 Cell Line 2
Z80711 Z80711 CHEMBL613829 NCI/ADR-RES (Breast Carcinoma Cells) 2
Z80712 Z80712 CHEMBL614361 T47D (Breast Carcinoma Cells) 2
Z80752 Z80752 CHEMBL614380 Carcinoma Cell Line 2
Z80789 Z80789 CHEMBL614463 Colon 38 2
Z80815 Z80815 CHEMBL612247 D54 Cell Line 2
Z80830 Z80830 CHEMBL614641 Ehrlich (Ehrlich Ascites Carcinoma Cells) 2
Z80890 Z80890 CHEMBL614160 H350.3 (MTX-resistant Reuber Hepatoma Cells) 2
Z80893 Z80893 CHEMBL614784 H35 (Reuber Hepatoma Cells) 2
Z80920 Z80920 CHEMBL613855 HCC 2998 (Colon Adenocarcinoma Cells) 2
Z81020 Z81020 CHEMBL395 HepG2 (Hepatoblastoma Cells) 2
Z81072 Z81072 CHEMBL397 Jurkat (Acute Leukemic T-cells) 2
Z81126 Z81126 CHEMBL613998 KYSE-150 Cell Line 2
Z81128 Z81128 CHEMBL612701 KYSE-520 Cell Line 2
Z81130 Z81130 CHEMBL614012 KYSE-70 Cell Line 2
Z81184 Z81184 CHEMBL614096 LOX IMVI (Melanoma Cells) 2
Z81235 Z81235 CHEMBL612270 M4Beu Cell Line 2
Z81281 Z81281 CHEMBL614997 NCI-H23 (Non-small Cell Lung Carcinoma Cells) 2
Z81283 Z81283 CHEMBL614387 NCI-H522 (Non-small Cell Lung Carcinoma Cells) 2
Z81322 Z81322 CHEMBL614860 SF-539 (Glioblastoma Cells) 2
Z81325 Z81325 CHEMBL614300 SR (Leukemia Cells) 2
Z81331 Z81331 CHEMBL612262 SW-620 (Colon Adenocarcinoma Cells) 2
DRD1_RAT P18901 CHEMBL265 Dopamine D1 Receptor, Rat 1
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 1
KIT_HUMAN P10721 CHEMBL1936 Stem Cell Growth Factor Receptor, Human 1
TOP1_HUMAN P11387 CHEMBL1781 DNA Topoisomerase I, Human 1
TOP1_MOUSE Q04750 CHEMBL2814 DNA Topoisomerase I, Mouse 1
TOP2A_HUMAN P11388 CHEMBL1806 DNA Topoisomerase II Alpha, Human 1
TOP2A_MOUSE Q01320 CHEMBL3586 DNA Topoisomerase II Alpha, Mouse 1
TOP2B_HUMAN Q02880 CHEMBL3396 DNA Topoisomerase II Beta, Human 1
TOP2B_MOUSE Q64511 CHEMBL5564 DNA Topoisomerase II Beta, Mouse 1
Z100501 Z100501 CHEMBL613290 Lu1 (Lung Carcinoma Cells) 1
Z100733 Z100733 CHEMBL613866 CT26 (Colon Carcinoma Cells) 1
Z100752 Z100752 CHEMBL612568 Renca (Renal Carcinoma Cells) 1
Z103202 Z103202 CHEMBL1075387 8505C 1
Z103413 Z103413 CHEMBL1075598 SW948 1
Z50426 Z50426 CHEMBL612856 Plasmodium Falciparum (isolate K1 / Thailand) 1
Z50466 Z50466 CHEMBL368 Trypanosoma Cruzi 1
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 1
Z80026 Z80026 CHEMBL613860 AGS (Gastric Adenocarcinoma Cells) 1
Z80036 Z80036 CHEMBL614524 BaF3 (IL-3-dependent Pro-B-cells) 1
Z80068 Z80068 CHEMBL614542 CCRF-SB (Lymphoblastic Leukemia Cells) 1
Z80088 Z80088 CHEMBL613853 CHO (Ovarian Cells) 1
Z80089 Z80089 CHEMBL614555 CHO-AA8 1
Z80091 Z80091 CHEMBL614557 CHO-hD3 1
Z80113 Z80113 CHEMBL612519 Daoy (Medulloblastoma Cells) 1
Z80132 Z80132 CHEMBL614293 EL4 (Thymoma Cells) 1
Z80145 Z80145 CHEMBL614045 H69 1
Z80179 Z80179 CHEMBL614586 J82 (Bladder Carcinoma Cells) 1
Z80188 Z80188 CHEMBL614590 KB 3-1 (Cervical Epithelial Carcinoma Cells) 1
Z80243 Z80243 CHEMBL614334 MDA-MB-453 (Breast Adenocarcinoma Cells) 1
Z80284 Z80284 CHEMBL614176 MOLT-3 (T-lymphoblastic Leukemia Cells) 1
Z80288 Z80288 CHEMBL614133 MOVP-3 1
Z80295 Z80295 CHEMBL388 MT4 (Lymphocytes) 1
Z80414 Z80414 CHEMBL614628 Raji (B-lymphoblastic Cells) 1
Z80427 Z80427 CHEMBL614879 RKO (Colon Carcinoma) 1
Z80475 Z80475 CHEMBL613834 SK-BR-3 (Breast Adenocarcinoma) 1
Z80490 Z80490 CHEMBL614923 SK-MES-1 1
Z80491 Z80491 CHEMBL614163 SK-N-MC (Neuroepithelioma Cells) 1
Z80493 Z80493 CHEMBL614925 SK-OV-3 (Ovarian Carcinoma Cells) 1
Z80509 Z80509 CHEMBL614935 SNU-638 (Gastric Carcinoma Cells) 1
Z80525 Z80525 CHEMBL614055 SW48 1
Z80548 Z80548 CHEMBL614245 THP-1 (Acute Monocytic Leukemia Cells) 1
Z80559 Z80559 CHEMBL615021 U251 1
Z80578 Z80578 CHEMBL612800 UV4 1
Z80600 Z80600 CHEMBL613533 XF498 (Glioma Cells) 1
Z80601 Z80601 CHEMBL614060 XRS6 1
Z80608 Z80608 CHEMBL614393 ZR-75-1 (Breast Carcinoma Cells) 1
Z80768 Z80768 CHEMBL614455 CH1 (Ovarian Carcinoma Cells) 1
Z80784 Z80784 CHEMBL614462 Col2 (Colon Carcinoma Cells) 1
Z80807 Z80807 CHEMBL614475 D283 Cell Line 1
Z80819 Z80819 CHEMBL614484 J774.2 1
Z80846 Z80846 CHEMBL614493 F460pv8/eto Cell Line 1
Z80852 Z80852 CHEMBL614069 A-431 (Epidermoid Carcinoma Cells) 1
Z80866 Z80866 CHEMBL612707 GLC4 Cell Line 1
Z80887 Z80887 CHEMBL614802 H2981 Cell Line 1
Z80889 Z80889 CHEMBL614803 NCI-H322M (Non-small Cell Lung Carcinoma Cells) 1
Z80896 Z80896 CHEMBL614805 NCI-H69 (Small Cell Lung Carcinoma Cells) 1
Z80901 Z80901 CHEMBL614392 HaCaT (Keratinocytes) 1
Z81034 Z81034 CHEMBL614004 A2780 (Ovarian Carcinoma Cells) 1
Z81043 Z81043 CHEMBL613969 N592 1
Z81146 Z81146 CHEMBL614066 LCLC-103H Cell Line 1
Z81160 Z81160 CHEMBL614088 Lewis Lung Carcinoma Cell Line 1
Z81170 Z81170 CHEMBL612518 LNCaP (Prostate Carcinoma) 1
Z81244 Z81244 CHEMBL614123 J774 (Macrophage Cells) 1
Z81277 Z81277 CHEMBL613287 NCI-N417 1
Z81280 Z81280 CHEMBL614740 NCI-H226 (Non-small Cell Lung Carcinoma Cells) 1
Z81284 Z81284 CHEMBL614999 NCI-H647 1
Z81338 Z81338 CHEMBL614309 T-cells 1