ZINC 12

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Quick Search ZINC ID or SMILES

Names
Compounds (955)
Reactome (0)
Related By:
Pathway (0)
Organism (-1)
Gene (-1)
Org. Clust. (3)
ChEMBL (86)
Rings (47)

Neuronal Acetylcholine Receptor; Alpha4/beta2 (955 Compounds)

Swissprot:: Z104290
Stitch:: Z104290
UniProt:: Z104290
ChEMBL:: CHEMBL1907596

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	955	102	19	12
Binding ≤ 1μM	824	79	18	12
Functional ≤ 10μM	37	4	3	1

Clustered By Gene (0)

Clustered By Organism (3)

Code	Description	Substances	Purchasable	Natural	In Man
Z104290-1-O	Neuronal Acetylcholine Receptor; Alpha4/beta2 (cluster #1 Of 4), Other	669	86	17	8
Z104290-2-O	Neuronal Acetylcholine Receptor; Alpha4/beta2 (cluster #2 Of 4), Other	27	1	0	0
Z104290-3-O	Neuronal Acetylcholine Receptor; Alpha4/beta2 (cluster #3 Of 4), Other	5	3	3	3
Z104290-4-O	Neuronal Acetylcholine Receptor; Alpha4/beta2 (cluster #4 Of 4), Other	275	19	3	4

Uniprot	Swissprot	Chembl	Description	Number Shared
ACHA7_RAT	Q05941	CHEMBL4980	Neuronal Acetylcholine Receptor Protein Alpha-7 Subunit, Rat	171
Z104283	Z104283	CHEMBL1907589	Neuronal Acetylcholine Receptor; Alpha4/beta2	88
Z104281	Z104281	CHEMBL1907587	Neuronal Acetylcholine Receptor; Alpha3/beta2	81
Z104289	Z104289	CHEMBL1907595	Neuronal Acetylcholine Receptor; Alpha4/beta4	81
Z104286	Z104286	CHEMBL1907592	Neuronal Acetylcholine Receptor; Alpha2/beta2	79
Z104287	Z104287	CHEMBL1907593	Neuronal Acetylcholine Receptor; Alpha3/beta4	76
ACHB4_RAT	P12392	CHEMBL2658	Neuronal Acetylcholine Receptor Protein Beta-4 Subunit, Rat	70
Z104284	Z104284	CHEMBL1907590	Neuronal Acetylcholine Receptor; Alpha2/beta4	62
ACHB2_RAT	P12390	CHEMBL3001	Neuronal Acetylcholine Receptor Protein Beta-2 Subunit, Rat	56
ACHA4_HUMAN	P43681	CHEMBL1882	Neuronal Acetylcholine Receptor Protein Alpha-4 Subunit, Human	55
ACHA4_RAT	P09483	CHEMBL307	Neuronal Acetylcholine Receptor Protein Alpha-4 Subunit, Rat	52
ACHA3_RAT	P04757	CHEMBL3818	Neuronal Acetylcholine Receptor Protein Alpha-3 Subunit, Rat	46
ACHD_TORCA	P02718	CHEMBL3916	Acetylcholine Receptor Protein Delta Chain, Torca	42
ACHA2_RAT	P12389	CHEMBL2584	Neuronal Acetylcholine Receptor Protein Alpha-2 Subunit, Rat	36
ACH10_RAT	Q9JLB5	CHEMBL3461	Neuronal Acetylcholine Receptor Protein Alpha-10 Subunit, Rat	32
ACHA5_RAT	P20420	CHEMBL4960	Neuronal Acetylcholine Receptor Protein Alpha-5 Subunit, Rat	31
ACHA6_RAT	P43143	CHEMBL4747	Neuronal Acetylcholine Receptor Protein Alpha-6 Subunit, Rat	31
ACHA9_RAT	P43144	CHEMBL2585	Neuronal Acetylcholine Receptor Protein Alpha-9 Subunit, Rat	31
ACHA_RAT	P25108	CHEMBL3599	Acetylcholine Receptor Protein Alpha Chain, Rat	31
ACHB3_RAT	P12391	CHEMBL4568	Neuronal Acetylcholine Receptor Protein Beta-3 Subunit, Rat	31
ACHB_RAT	P25109	CHEMBL2666	Acetylcholine Receptor Protein Beta Chain, Rat	31
ACHA7_HUMAN	P36544	CHEMBL2492	Neuronal Acetylcholine Receptor Protein Alpha-7 Subunit, Human	24
ACHA3_HUMAN	P32297	CHEMBL3068	Neuronal Acetylcholine Receptor Protein Alpha-3 Subunit, Human	22
ACHB2_HUMAN	P17787	CHEMBL1883	Neuronal Acetylcholine Receptor Protein Beta-2 Subunit, Human	21
ACHB4_HUMAN	P30926	CHEMBL3002	Neuronal Acetylcholine Receptor Protein Beta-4 Subunit, Human	18
Z104288	Z104288	CHEMBL1907594	Neuronal Acetylcholine Receptor; Alpha3/beta4	18
ACHA_TORCA	P02710	CHEMBL3097	Acetylcholine Receptor Protein Alpha Chain, Torca	17
ACHA2_HUMAN	Q15822	CHEMBL1794	Neuronal Acetylcholine Receptor Protein Alpha-2 Subunit, Human	16
ACHB_TORCA	P02712	CHEMBL3803	Acetylcholine Receptor Protein Beta Chain, Torca	15
ACHG_TORCA	P02714	CHEMBL4019	Acetylcholine Receptor Protein Gamma Chain, Torca	15
Z104303	Z104303	CHEMBL1907609	Muscarinic Acetylcholine Receptor	9
ACHA4_MOUSE	O70174	CHEMBL4457	Neuronal Acetylcholine Receptor Protein Alpha-4 Subunit, Mouse	8
ACM1_RAT	P08482	CHEMBL276	Muscarinic Acetylcholine Receptor M1, Rat	8
ACM2_HUMAN	P08172	CHEMBL211	Muscarinic Acetylcholine Receptor M2, Human	8
ACM2_RAT	P10980	CHEMBL309	Muscarinic Acetylcholine Receptor M2, Rat	8
ACM4_HUMAN	P08173	CHEMBL1821	Muscarinic Acetylcholine Receptor M4, Human	8
ACM4_RAT	P08485	CHEMBL317	Muscarinic Acetylcholine Receptor M4, Rat	8
Q8BGP7_MOUSE	Q8BGP7	CHEMBL2235	Neuronal Acetylcholine Receptor Protein Beta-2 Subunit, Mouse	8
ACHB3_HUMAN	Q05901	CHEMBL2586	Neuronal Acetylcholine Receptor Protein Beta-3 Subunit, Human	7
ACM1_HUMAN	P11229	CHEMBL216	Muscarinic Acetylcholine Receptor M1, Human	7
ACHD_HUMAN	Q07001	CHEMBL3011	Acetylcholine Receptor Protein Delta Chain, Human	6
VMAT2_RAT	Q01827	CHEMBL4828	Synaptic Vesicular Amine Transporter, Rat	6
Z104282	Z104282	CHEMBL1907588	Acetylcholine Receptor; Alpha1/beta1/delta/gamma	6
ACH10_HUMAN	Q9GZZ6	CHEMBL2551	Neuronal Acetylcholine Receptor Protein Alpha-10 Subunit, Human	5
ACHA5_HUMAN	P30532	CHEMBL2454	Neuronal Acetylcholine Receptor Protein Alpha-5 Subunit, Human	5
ACHA6_HUMAN	Q15825	CHEMBL2356	Neuronal Acetylcholine Receptor Protein Alpha-6 Subunit, Human	5
ACHA_HUMAN	P02708	CHEMBL4808	Acetylcholine Receptor Protein Alpha Chain, Human	5
ACM3_HUMAN	P20309	CHEMBL245	Muscarinic Acetylcholine Receptor M3, Human	5
ACHB_HUMAN	P11230	CHEMBL3355	Acetylcholine Receptor Protein Beta Chain, Human	4
ACHE_HUMAN	Q04844	CHEMBL2484	Acetylcholine Receptor Protein Epsilon Chain, Human	4
ACHG_HUMAN	P07510	CHEMBL2613	Acetylcholine Receptor Protein Gamma Chain, Human	4
ACM3_RAT	P08483	CHEMBL320	Muscarinic Acetylcholine Receptor M3, Rat	4
SC6A3_RAT	P23977	CHEMBL338	Dopamine Transporter, Rat	4
VMAT2_HUMAN	Q05940	CHEMBL1893	Synaptic Vesicular Amine Transporter, Human	4
Z50597	Z50597	CHEMBL376	Rattus Norvegicus	4
ACM5_HUMAN	P08912	CHEMBL2035	Muscarinic Acetylcholine Receptor M5, Human	3
SC6A4_RAT	P31652	CHEMBL313	Serotonin Transporter, Rat	3
Z104285	Z104285	CHEMBL1907591	Neuronal Acetylcholine Receptor; Alpha4/beta4	3
Z81074	Z81074	CHEMBL614687	K177cell Line	3
ACHA7_MOUSE	P49582	CHEMBL3365	Neuronal Acetylcholine Receptor Protein Alpha-7 Subunit, Mouse	2
ACHP_LYMST	P58154	CHEMBL6084	Acetylcholine-binding Protein, Lymst	2
ACM1_MOUSE	P12657	CHEMBL3733	Muscarinic Acetylcholine Receptor M1, Mouse	2
ADA2A_RAT	P22909	CHEMBL327	Alpha-2a Adrenergic Receptor, Rat	2
ADA2B_RAT	P19328	CHEMBL266	Alpha-2b Adrenergic Receptor, Rat	2
ADA2C_RAT	P22086	CHEMBL314	Alpha-2c Adrenergic Receptor, Rat	2
KCNH2_HUMAN	Q12809	CHEMBL240	HERG, Human	2
OPRK_HUMAN	P41145	CHEMBL237	Kappa Opioid Receptor, Human	2
OPRM_HUMAN	P35372	CHEMBL233	Mu Opioid Receptor, Human	2
OPRX_HUMAN	P41146	CHEMBL2014	Nociceptin Receptor, Human	2
Z80175	Z80175	CHEMBL614585	IMR-32 (Neuroblastoma Cells)	2
Z80545	Z80545	CHEMBL615012	TE-671	2
5HT3A_HUMAN	P46098	CHEMBL1899	Serotonin 3a (5-HT3a) Receptor, Human	1
5HT3B_HUMAN	O95264	CHEMBL3895	Serotonin 3b (5-HT3b) Receptor, Human	1
5HT3C_HUMAN	Q8WXA8	CHEMBL4795	Serotonin 3c (5-HT3c) Receptor, Human	1
5HT3D_HUMAN	Q70Z44	CHEMBL4673	Serotonin 3d (5-HT3d) Receptor, Human	1
5HT3E_HUMAN	A5X5Y0	CHEMBL3812	Serotonin 3e (5-HT3e) Receptor, Human	1
ACES_MOUSE	P21836	CHEMBL3198	Acetylcholinesterase, Mouse	1
ACHA6_MOUSE	Q9R0W9	CHEMBL6183	Neuronal Acetylcholine Receptor Subunit Alpha-6, Mouse	1
ACHA9_HUMAN	Q9UGM1	CHEMBL2184	Neuronal Acetylcholine Receptor Protein Alpha-9 Subunit, Human	1
ACHB3_MOUSE	Q8BMN3	CHEMBL1781863	Neuronal Acetylcholine Receptor Subunit Beta-3, Mouse	1
ACHB4_MOUSE	Q8R493	CHEMBL1255157	Neuronal Acetylcholine Receptor Subunit Beta-4, Mouse	1
ACM2_MOUSE	Q9ERZ4	CHEMBL3197	Muscarinic Acetylcholine Receptor M2, Mouse	1
ADA1A_BOVIN	P18130	CHEMBL4892	Alpha-1a Adrenergic Receptor, Bovin	1
ADA2A_BOVIN	Q28838	CHEMBL4744	Alpha-2a Adrenergic Receptor, Bovin	1
ADA2B_BOVIN	O77700	CHEMBL3523	Alpha-2b Adrenergic Receptor, Bovin	1
Z50594	Z50594	CHEMBL375	Mus Musculus	1