UCSF

Glutamate NMDA Receptor (1,991 Compounds)

Swissprot:
Z104302
Stitch:
Z104302
UniProt:
Z104302
ChEMBL:
CHEMBL1907608

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 1,991 146 47 42
Binding ≤ 1μM 1,365 77 28 26
Functional ≤ 10μM 225 29 16 11

Reactome Network (0)

Clustered By Gene (0)

Clustered By Organism (6)

Code Description Substances Purchasable Natural In Man
Z104302-1-O Glutamate NMDA Receptor (cluster #1 Of 7), Other 1,192 55 13 14
Z104302-2-O Glutamate NMDA Receptor (cluster #2 Of 7), Other 60 7 7 8
Z104302-3-O Glutamate NMDA Receptor (cluster #3 Of 7), Other 276 44 26 13
Z104302-4-O Glutamate NMDA Receptor (cluster #4 Of 7), Other 277 31 4 3
Z104302-5-O Glutamate NMDA Receptor (cluster #5 Of 7), Other 16 3 0 1
Z104302-6-O Glutamate NMDA Receptor (cluster #6 Of 7), Other 13 1 1 1
Z104302-7-O Glutamate NMDA Receptor (cluster #7 Of 7), Other 183 13 1 3
Uniprot Swissprot Chembl Description Number Shared
GRIA2_RAT P19491 CHEMBL3503 Glutamate Receptor Ionotropic, AMPA 2, Rat 168
GRIA3_RAT P19492 CHEMBL3504 Glutamate Receptor Ionotropic, AMPA 3, Rat 168
GRIA4_RAT P19493 CHEMBL3505 Glutamate Receptor Ionotropic, AMPA 4, Rat 168
SGMR1_HUMAN Q99720 CHEMBL287 Sigma Opioid Receptor, Human 149
GRIA1_MOUSE P23818 CHEMBL3502 Glutamate Receptor Ionotropic, AMPA 1, Mouse 143
NMDZ1_RAT P35439 CHEMBL330 Glutamate (NMDA) Receptor Subunit Zeta 1, Rat 105
NMDZ1_HUMAN Q05586 CHEMBL2015 Glutamate (NMDA) Receptor Subunit Zeta 1, Human 96
NMDE2_HUMAN Q13224 CHEMBL1904 Glutamate [NMDA] Receptor Subunit Epsilon 2, Human 91
NMD3B_HUMAN O60391 CHEMBL2913 Glutamate [NMDA] Receptor Subunit 3B, Human 90
NMDE1_HUMAN Q12879 CHEMBL1972 Glutamate [NMDA] Receptor Subunit Epsilon 1, Human 90
NMDE3_HUMAN Q14957 CHEMBL4109 Glutamate [NMDA] Receptor Subunit Epsilon 3, Human 90
NMDE4_HUMAN O15399 CHEMBL2591 Glutamate [NMDA] Receptor Subunit Epsilon 4, Human 90
NMD3A_HUMAN Q8TCU5 CHEMBL4787 Glutamate [NMDA] Receptor Subunit 3A, Human 88
GRIA1_RAT P19490 CHEMBL3753 Glutamate Receptor Ionotropic, AMPA 1, Rat 40
NMDE2_RAT Q00960 CHEMBL311 Glutamate [NMDA] Receptor Subunit Epsilon 2, Rat 33
OPRM_RAT P33535 CHEMBL270 Mu Opioid Receptor, Rat 32
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 30
NMDE3_RAT Q00961 CHEMBL401 Glutamate [NMDA] Receptor Subunit Epsilon 3, Rat 28
GRID1_HUMAN Q9ULK0 CHEMBL2936 Glutamate Receptor Delta-1 Subunit, Human 25
GRIK1_RAT P22756 CHEMBL2919 Glutamate Receptor Ionotropic Kainate 1, Rat 23
GRIK2_RAT P42260 CHEMBL3607 Glutamate Receptor Ionotropic Kainate 2, Rat 23
GRIK3_RAT P42264 CHEMBL3744 Glutamate Receptor Ionotropic Kainate 3, Rat 23
GRIK4_RAT Q01812 CHEMBL3044 Glutamate Receptor Ionotropic Kainate 4, Rat 23
GRIK5_RAT Q63273 CHEMBL4041 Glutamate Receptor Ionotropic Kainate 5, Rat 23
OPRD_HUMAN P41143 CHEMBL236 Delta Opioid Receptor, Human 23
OPRK_HUMAN P41145 CHEMBL237 Kappa Opioid Receptor, Human 23
OPRM_HUMAN P35372 CHEMBL233 Mu Opioid Receptor, Human 23
NMDE1_RAT Q00959 CHEMBL310 Glutamate [NMDA] Receptor Subunit Epsilon 1, Rat 22
NMDE4_RAT Q62645 CHEMBL303 Glutamate [NMDA] Receptor Subunit Epsilon 4, Rat 20
NMD3B_RAT Q8VHN2 CHEMBL282 Glutamate [NMDA] Receptor Subunit 3B, Rat 16
NMD3A_RAT Q9R1M7 CHEMBL342 Glutamate [NMDA] Receptor Subunit 3A, Rat 15
Z104304 Z104304 CHEMBL1907610 Adrenergic Receptor Alpha-1 15
GRIA1_HUMAN P42261 CHEMBL2009 Glutamate Receptor Ionotropic, AMPA 1, Human 14
GRIA2_HUMAN P42262 CHEMBL4016 Glutamate Receptor Ionotropic, AMPA 2, Human 14
GRIA4_HUMAN P48058 CHEMBL3190 Glutamate Receptor Ionotropic, AMPA 4, Human 14
GRIA3_HUMAN P42263 CHEMBL3595 Glutamate Receptor Ionotropic, AMPA 3, Human 12
SGMR1_RAT Q9R0C9 CHEMBL3602 Sigma Opioid Receptor, Rat 11
SCN2A_RAT P04775 CHEMBL3399 Sodium Channel Protein Type II Alpha Subunit, Rat 10
Z104297 Z104297 CHEMBL1907603 Glutamate NMDA Receptor; GRIN1/GRIN2B 10
A2AIR5_MOUSE A2AIR5 CHEMBL2562 Glutamate [NMDA] Receptor Subunit 3A, Mouse 9
NMD3B_MOUSE Q91ZU9 CHEMBL2557 Glutamate [NMDA] Receptor Subunit 3B, Mouse 9
NMDE1_MOUSE P35436 CHEMBL2521 Glutamate [NMDA] Receptor Subunit Epsilon 1, Mouse 9
NMDE2_MOUSE Q01097 CHEMBL3442 Glutamate [NMDA] Receptor Subunit Epsilon 2, Mouse 9
NMDE3_MOUSE Q01098 CHEMBL3555 Glutamate [NMDA] Receptor Subunit Epsilon 3, Mouse 9
NMDE4_MOUSE Q03391 CHEMBL2893 Glutamate [NMDA] Receptor Subunit Epsilon 4, Mouse 9
NMDZ1_MOUSE P35438 CHEMBL2895 Glutamate (NMDA) Receptor Subunit Zeta 1, Mouse 9
SC6A4_RAT P31652 CHEMBL313 Serotonin Transporter, Rat 9
GRIK1_HUMAN P39086 CHEMBL1918 Glutamate Receptor Ionotropic Kainate 1, Human 7
GRIK5_HUMAN Q16478 CHEMBL2675 Glutamate Receptor Ionotropic Kainate 5, Human 7
SGMR1_CAVPO Q60492 CHEMBL4153 Sigma-1 Receptor, Guinea Pig 7
5HT1A_RAT P19327 CHEMBL273 Serotonin 1a (5-HT1a) Receptor, Rat 6
GRIK2_HUMAN Q13002 CHEMBL3683 Glutamate Receptor Ionotropic Kainate 2, Human 6
GRIK3_HUMAN Q13003 CHEMBL3684 Glutamate Receptor Ionotropic Kainate 3, Human 6
Z50594 Z50594 CHEMBL375 Mus Musculus 6
GRINA_HUMAN Q7Z429 CHEMBL4704 Glutamate [NMDA] Receptor Associated Protein 1, Human 5
Z50425 Z50425 CHEMBL364 Plasmodium Falciparum 5
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 4
GRIK4_HUMAN Q16099 CHEMBL2829 Glutamate Receptor Ionotropic Kainate 4, Human 4
TYTR_TRYCR P28593 CHEMBL5131 Trypanothione Reductase, Trycr 4
Z100491 Z100491 CHEMBL613288 Sigma 2 Receptor 4
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 3
EBP_CAVPO Q60490 CHEMBL5525 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase, Guinea Pig 3
GLRA1_RAT P07727 CHEMBL3246 Glycine Receptor Alpha-1 Chain, Rat 3
GLRA2_RAT P22771 CHEMBL2328 Glycine Receptor Alpha-2 Chain, Rat 3
GLRA3_RAT P24524 CHEMBL2677 Glycine Receptor Alpha-3 Chain, Rat 3
GLRB_RAT P20781 CHEMBL4126 Glycine Receptor Beta Chain, Rat 3
GRM1_HUMAN Q13255 CHEMBL3772 Metabotropic Glutamate Receptor 1, Human 3
GRM1_RAT P23385 CHEMBL4477 Metabotropic Glutamate Receptor 1, Rat 3
GRM3_RAT P31422 CHEMBL3067 Metabotropic Glutamate Receptor 3, Rat 3
GRM5_RAT P31424 CHEMBL2564 Metabotropic Glutamate Receptor 5, Rat 3
OPRD_RAT P33533 CHEMBL269 Delta Opioid Receptor, Rat 3
OPRK_RAT P34975 CHEMBL3614 Kappa Opioid Receptor, Rat 3
PCP_HUMAN P42785 CHEMBL2335 Lysosomal Pro-X Carboxypeptidase, Human 3
SC6A4_HUMAN P31645 CHEMBL228 Serotonin Transporter, Human 3
ACM1_RAT P08482 CHEMBL276 Muscarinic Acetylcholine Receptor M1, Rat 2
ACM2_RAT P10980 CHEMBL309 Muscarinic Acetylcholine Receptor M2, Rat 2
CNR1_RAT P20272 CHEMBL3571 Cannabinoid CB1 Receptor, Rat 2
CNR2_HUMAN P34972 CHEMBL253 Cannabinoid CB2 Receptor, Human 2
CNR2_RAT Q9QZN9 CHEMBL2470 Cannabinoid CB2 Receptor, Rat 2
F16P1_HUMAN P09467 CHEMBL3975 Fructose-1,6-bisphosphatase, Human 2
F16P2_HUMAN O00757 CHEMBL3877 Fructose-1,6-bisphosphatase 2, Human 2
GLRA4_MOUSE Q61603 CHEMBL3500 Glycine Receptor Alpha-4 Chain, Mouse 2
GRIA2_MOUSE P23819 CHEMBL3205 Glutamate Receptor Ionotropic, AMPA 2, Mouse 2
GRIA3_MOUSE Q9Z2W9 CHEMBL3624 Glutamate Receptor Ionotropic, AMPA 3, Mouse 2
GRIA4_MOUSE Q9Z2W8 CHEMBL3615 Glutamate Receptor Ionotropic, AMPA 4, Mouse 2
GRM2_HUMAN Q14416 CHEMBL5137 Metabotropic Glutamate Receptor 2, Human 2
GRM2_RAT P31421 CHEMBL2851 Metabotropic Glutamate Receptor 2, Rat 2
GRM4_HUMAN Q14833 CHEMBL2736 Metabotropic Glutamate Receptor 4, Human 2
GRM5_HUMAN P41594 CHEMBL3227 Metabotropic Glutamate Receptor 5, Human 2
OPRD_MOUSE P32300 CHEMBL3222 Delta Opioid Receptor, Mouse 2
OPRK_CAVPO P41144 CHEMBL3952 Kappa Opioid Receptor, Guinea Pig 2
OPRK_MOUSE P33534 CHEMBL4329 Kappa Opioid Receptor, Mouse 2
OPRM_CAVPO P97266 CHEMBL4354 Mu Opioid Receptor, Guinea Pig 2
OPRM_MOUSE P42866 CHEMBL2858 Mu Opioid Receptor, Mouse 2
Q9WTR4_RAT Q9WTR4 CHEMBL304 Norepinephrine Transporter, Rat 2
SC6A2_HUMAN P23975 CHEMBL222 Norepinephrine Transporter, Human 2
SC6A3_RAT P23977 CHEMBL338 Dopamine Transporter, Rat 2
SGMR1_MOUSE O55242 CHEMBL3465 Sigma Opioid Receptor, Mouse 2
TRY1_HUMAN P07477 CHEMBL209 Trypsin I, Human 2
Z100250 Z100250 CHEMBL612514 Calf Thymus DNA 2
Z104298 Z104298 CHEMBL1907604 Glutamate NMDA Receptor; GRIN1/GRIN2A 2
5HT1A_HUMAN P08908 CHEMBL214 Serotonin 1a (5-HT1a) Receptor, Human 1
5HT2A_RAT P14842 CHEMBL322 Serotonin 2a (5-HT2a) Receptor, Rat 1
5HT2B_HUMAN P41595 CHEMBL1833 Serotonin 2b (5-HT2b) Receptor, Human 1
5HT2B_RAT P30994 CHEMBL323 Serotonin 2b (5-HT2b) Receptor, Rat 1
5HT2C_HUMAN P28335 CHEMBL225 Serotonin 2c (5-HT2c) Receptor, Human 1
5HT2C_RAT P08909 CHEMBL324 Serotonin 2c (5-HT2c) Receptor, Rat 1
5HT6R_HUMAN P50406 CHEMBL3371 Serotonin 6 (5-HT6) Receptor, Human 1
5HT7R_HUMAN P34969 CHEMBL3155 Serotonin 7 (5-HT7) Receptor, Human 1
5HT7R_RAT P32305 CHEMBL3223 Serotonin 7 (5-HT7) Receptor, Rat 1
A3EZI9_9HEPC A3EZI9 CHEMBL4893 Hepatitis C Virus NS3 Protease/helicase, 9hepc 1
ACES_BOVIN P23795 CHEMBL4768 Acetylcholinesterase, Bovin 1
ACES_ELEEL O42275 CHEMBL4078 Acetylcholinesterase, Eleel 1
ACES_HUMAN P22303 CHEMBL220 Acetylcholinesterase, Human 1
ACES_MOUSE P21836 CHEMBL3198 Acetylcholinesterase, Mouse 1
ACES_TORCA P04058 CHEMBL4780 Acetylcholinesterase, Torca 1
ACM1_MOUSE P12657 CHEMBL3733 Muscarinic Acetylcholine Receptor M1, Mouse 1
ACM2_MOUSE Q9ERZ4 CHEMBL3197 Muscarinic Acetylcholine Receptor M2, Mouse 1
ACM3_MOUSE Q9ERZ3 CHEMBL5105 Muscarinic Acetylcholine Receptor M3, Mouse 1
ACM4_MOUSE P32211 CHEMBL4572 Muscarinic Acetylcholine Receptor M4, Mouse 1
ACM5_MOUSE Q920H4 CHEMBL2324 Muscarinic Acetylcholine Receptor M5, Mouse 1
ADA2A_RAT P22909 CHEMBL327 Alpha-2a Adrenergic Receptor, Rat 1
ADA2B_RAT P19328 CHEMBL266 Alpha-2b Adrenergic Receptor, Rat 1
ADA2C_RAT P22086 CHEMBL314 Alpha-2c Adrenergic Receptor, Rat 1
ADCY2_RAT P26769 CHEMBL2958 Adenylate Cyclase Type II, Rat 1
ADCY3_RAT P21932 CHEMBL4864 Adenylate Cyclase Type III, Rat 1
ADCY4_RAT P26770 CHEMBL2879 Adenylate Cyclase Type IV, Rat 1
ADCY5_RAT Q04400 CHEMBL2880 Adenylate Cyclase Type V, Rat 1
ADCY6_RAT Q03343 CHEMBL2975 Adenylate Cyclase Type VI, Rat 1
ADCY8_RAT P40146 CHEMBL3082 Adenylate Cyclase Type VIII, Rat 1
CAH14_HUMAN Q9ULX7 CHEMBL3510 Carbonic Anhydrase XIV, Human 1
CAH4_HUMAN P22748 CHEMBL3729 Carbonic Anhydrase IV, Human 1
CAH5A_HUMAN P35218 CHEMBL4789 Carbonic Anhydrase VA, Human 1
CAH5B_HUMAN Q9Y2D0 CHEMBL3969 Carbonic Anhydrase VB, Human 1
CAH6_HUMAN P23280 CHEMBL3025 Carbonic Anhydrase VI, Human 1
CAH7_HUMAN P43166 CHEMBL2326 Carbonic Anhydrase VII, Human 1
CALM_HUMAN P62158 CHEMBL6093 Calmodulin, Human 1
CASP2_HUMAN P42575 CHEMBL4884 Caspase-2, Human 1
CHLE_MOUSE Q03311 CHEMBL2528 Butyrylcholinesterase, Mouse 1
CNR1_HUMAN P21554 CHEMBL218 Cannabinoid CB1 Receptor, Human 1
D4A3N4_RAT D4A3N4 CHEMBL2679 Brain Adenylate Cyclase 1, Rat 1
DRD1_BOVIN Q95136 CHEMBL2967 Dopamine D1 Receptor, Bovin 1
DRD1_HUMAN P21728 CHEMBL2056 Dopamine D1 Receptor, Human 1
DRD1_RAT P18901 CHEMBL265 Dopamine D1 Receptor, Rat 1
DRD2_BOVIN P20288 CHEMBL3998 Dopamine D2 Receptor, Bovin 1
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 1
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 1
DRD3_RAT P19020 CHEMBL3138 Dopamine D3 Receptor, Rat 1
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 1
DRD4_RAT P30729 CHEMBL3361 Dopamine D4 Receptor, Rat 1
DRD5_HUMAN P21918 CHEMBL1850 Dopamine D5 Receptor, Human 1
DRD5_RAT P25115 CHEMBL2281 Dopamine D5 Receptor, Rat 1
EAA2_HUMAN P43004 CHEMBL4973 Excitatory Amino Acid Transporter 2, Human 1
EAA3_HUMAN P43005 CHEMBL2721 Excitatory Amino Acid Transporter 3, Human 1
EAA3_RAT P51907 CHEMBL3113 Excitatory Amino Acid Transporter 3, Rat 1
EBP_HUMAN Q15125 CHEMBL4931 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase, Human 1
ERG2_YEAST P32352 CHEMBL3224 C-8 Sterol Isomerase, Yeast 1
F16P1_PIG P00636 CHEMBL2263 Fructose-1,6-bisphosphatase, Pig 1
GBRA2_RAT P23576 CHEMBL341 GABA Receptor Alpha-2 Subunit, Rat 1
GRL1A_RAT Q91XQ4 CHEMBL3059 Glutamate [NMDA] Receptor-like 1A, Rat 1
GRM3_HUMAN Q14832 CHEMBL2888 Metabotropic Glutamate Receptor 3, Human 1
GRM4_RAT P31423 CHEMBL2787 Metabotropic Glutamate Receptor 4, Rat 1
GRM6_HUMAN O15303 CHEMBL4573 Metabotropic Glutamate Receptor 6, Human 1
GRM6_RAT P35349 CHEMBL3842 Metabotropic Glutamate Receptor 6, Rat 1
GRM8_HUMAN O00222 CHEMBL3228 Metabotropic Glutamate Receptor 8, Human 1
GRM8_MOUSE P47743 CHEMBL4626 Metabotropic Glutamate Receptor 8, Mouse 1
GRM8_RAT P70579 CHEMBL2718 Metabotropic Glutamate Receptor 8, Rat 1
HRH1_HUMAN P35367 CHEMBL231 Histamine H1 Receptor, Human 1
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 1
MDR1_HUMAN P08183 CHEMBL4302 P-glycoprotein 1, Human 1
MDTK_ECOLI P37340 CHEMBL1681613 Multidrug Resistance Protein MdtK, Ecoli 1
MURI_HELPY P56068 CHEMBL6078 Glutamate Racemase, Helpy 1
PDR5_YEAST P33302 CHEMBL1697658 Pleiotropic ABC Efflux Transporter Of Multiple Drugs, Yeast 1
PRIO_HUMAN P04156 CHEMBL4869 Prion Protein, Human 1
Q8CFM9_RAT Q8CFM9 CHEMBL3940 Adenylate Cyclase Type VII, Rat 1
S100B_HUMAN P04271 CHEMBL4300 S-100 Protein Beta Chain, Human 1
SC6A3_HUMAN Q01959 CHEMBL238 Dopamine Transporter, Human 1
SCN1A_HUMAN P35498 CHEMBL1845 Sodium Channel Protein Type I Alpha Subunit, Human 1
SCN1A_RAT P04774 CHEMBL4906 Sodium Channel Protein Type I Alpha Subunit, Rat 1
SCN2A_HUMAN Q99250 CHEMBL4187 Sodium Channel Protein Type II Alpha Subunit, Human 1
SCN3A_HUMAN Q9NY46 CHEMBL5163 Sodium Channel Protein Type III Alpha Subunit, Human 1
SCN3A_RAT P08104 CHEMBL4966 Sodium Channel Protein Type III Alpha Subunit, Rat 1
SCN8A_HUMAN Q9UQD0 CHEMBL5202 Sodium Channel Protein Type VIII Alpha Subunit, Human 1
SCN8A_RAT O88420 CHEMBL2752 Sodium Channel Protein Type VIII Alpha Subunit, Rat 1
ST14_HUMAN Q9Y5Y6 CHEMBL3018 Matriptase, Human 1
TERT_HUMAN O14746 CHEMBL2916 Telomerase Reverse Transcriptase, Human 1
THA_HUMAN P10827 CHEMBL1860 Thyroid Hormone Receptor Alpha, Human 1
THB_HUMAN P10828 CHEMBL1947 Thyroid Hormone Receptor Beta-1, Human 1
TRPV1_RAT O35433 CHEMBL5102 Vanilloid Receptor, Rat 1
Z104303 Z104303 CHEMBL1907609 Muscarinic Acetylcholine Receptor 1
Z50643 Z50643 CHEMBL379 Hepatitis C Virus 1
Z80390 Z80390 CHEMBL390 PC-3 (Prostate Carcinoma Cells) 1

Most Common Rings