UCSF

Oryctolagus Cuniculus (21 Compounds)

Swissprot:
Z50592
Stitch:
Z50592
UniProt:
Z50592
ChEMBL:
CHEMBL374

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 21 3 2 2
Binding ≤ 1μM 9 3 2 2
Functional ≤ 10μM 1,696 105 64 71
ADME/T ≤ 10μM 0 0 0 0

Reactome Network (0)

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 87
Z50512 Z50512 CHEMBL369 Cavia Porcellus 82
P2Y12_HUMAN Q9H244 CHEMBL2001 Purinergic Receptor P2Y12, Human 71
Z50587 Z50587 CHEMBL372 Homo Sapiens 51
PTAFR_HUMAN P25105 CHEMBL250 Platelet Activating Factor Receptor, Human 37
CAC1C_HUMAN Q13936 CHEMBL1940 Voltage-gated L-type Calcium Channel Alpha-1C Subunit, Human 36
PDE3A_HUMAN Q14432 CHEMBL241 Phosphodiesterase 3A, Human 33
PDE3B_HUMAN Q13370 CHEMBL290 Phosphodiesterase 3B, Human 33
CAC1D_HUMAN Q01668 CHEMBL4138 Voltage-gated L-type Calcium Channel Alpha-1D Subunit, Human 32
CAC1S_HUMAN Q13698 CHEMBL3805 Voltage-gated L-type Calcium Channel Alpha-1S Subunit, Human 30
THAS_HUMAN P24557 CHEMBL1835 Thromboxane-A Synthase, Human 25
5HT2A_RAT P14842 CHEMBL322 Serotonin 2a (5-HT2a) Receptor, Rat 20
5HT2B_RAT P30994 CHEMBL323 Serotonin 2b (5-HT2b) Receptor, Rat 20
5HT2C_RAT P08909 CHEMBL324 Serotonin 2c (5-HT2c) Receptor, Rat 20
Z50425 Z50425 CHEMBL364 Plasmodium Falciparum 17
Z50212 Z50212 CHEMBL354 Escherichia Coli 16
AA1R_RABIT P34970 CHEMBL3947 Adenosine A1 Receptor, Rabit 14
AA2AR_HUMAN P29274 CHEMBL251 Adenosine A2a Receptor, Human 14
AA2BR_HUMAN P29275 CHEMBL255 Adenosine A2b Receptor, Human 14
AA3R_RABIT O02667 CHEMBL2603 Adenosine A3 Receptor, Rabit 14
Z80936 Z80936 CHEMBL614818 HEK293 (Embryonic Kidney Fibroblasts) 14
CAC1F_HUMAN O60840 CHEMBL5593 Voltage-gated L-type Calcium Channel Alpha-1F Subunit, Human 13
Z50588 Z50588 CHEMBL373 Canis Familiaris 12
Z80433 Z80433 CHEMBL614882 RPMI-8226 (Multiple Myeloma Cells) 12
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 11
ACM1_HUMAN P11229 CHEMBL216 Muscarinic Acetylcholine Receptor M1, Human 10
DRD1_RAT P18901 CHEMBL265 Dopamine D1 Receptor, Rat 8
Z50590 Z50590 CHEMBL613488 Sus Scrofa 8
Z80471 Z80471 CHEMBL614910 SH-SY5 (Bone Marrow Neuroblastoma Cells) 8
BKRB2_HUMAN P30411 CHEMBL3157 Bradykinin B2 Receptor, Human 7
DRD1_HUMAN P21728 CHEMBL2056 Dopamine D1 Receptor, Human 7
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 7
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 7
SRC_HUMAN P12931 CHEMBL267 Tyrosine-protein Kinase SRC, Human 6
Z102306 Z102306 CHEMBL613606 Aorta 6
BKRB1_HUMAN P46663 CHEMBL4308 Bradykinin B1 Receptor, Human 5
CAC1C_RABIT P15381 CHEMBL2830 Voltage-gated L-type Calcium Channel Alpha-1C Subunit, Rabit 5
CAC1C_RAT P22002 CHEMBL3762 Voltage-gated L-type Calcium Channel Alpha-1C Subunit, Rat 5
CAC1D_RAT P27732 CHEMBL4132 Voltage-gated L-type Calcium Channel Alpha-1D Subunit, Rat 5
DRD5_HUMAN P21918 CHEMBL1850 Dopamine D5 Receptor, Human 5
O77823_PIG O77823 CHEMBL3333 Phosphodiesterase 4A, Pig 5
PTAFR_RAT P46002 CHEMBL4127 Platelet Activating Factor Receptor, Rat 5
ACM3_HUMAN P20309 CHEMBL245 Muscarinic Acetylcholine Receptor M3, Human 4
AGTR1_RABIT P34976 CHEMBL3948 Angiotensin II Type 1a (AT-1a) Receptor, Rabit 4
CAC1E_RAT Q07652 CHEMBL4115 Voltage-gated R-type Calcium Channel Alpha-1E Subunit, Rat 4
PTAFR_MOUSE Q62035 CHEMBL3993 Platelet Activating Factor Receptor, Mouse 4
Z102256 Z102256 CHEMBL613450 Plasma 4
Z50466 Z50466 CHEMBL368 Trypanosoma Cruzi 4
Z80193 Z80193 CHEMBL386 L1210 (Lymphocytic Leukemia Cells) 4
Z80419 Z80419 CHEMBL614772 RBL-1 (Basophilic Leukemia Cells) 4
Z81205 Z81205 CHEMBL614106 Lvec Cell Line 4
Z81244 Z81244 CHEMBL614123 J774 (Macrophage Cells) 4
5HT1D_HUMAN P28221 CHEMBL1983 Serotonin 1d (5-HT1d) Receptor, Human 3
ACM4_HUMAN P08173 CHEMBL1821 Muscarinic Acetylcholine Receptor M4, Human 3
ACM5_HUMAN P08912 CHEMBL2035 Muscarinic Acetylcholine Receptor M5, Human 3
ADA2A_HUMAN P08913 CHEMBL1867 Alpha-2a Adrenergic Receptor, Human 3
ADA2C_HUMAN P18825 CHEMBL1916 Alpha-2c Adrenergic Receptor, Human 3
AGTR1_HUMAN P30556 CHEMBL227 Angiotensin II Type 1 Receptor, Human 3
AGTR2_HUMAN P50052 CHEMBL4607 Angiotensin II Type 2 (AT-2) Receptor, Human 3
CAC1S_RAT Q02485 CHEMBL4108 Voltage-gated L-type Calcium Channel Alpha-1S Subunit, Rat 3
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 3
PDE5A_HUMAN O76074 CHEMBL1827 Phosphodiesterase 5A, Human 3
TA2R_RAT P34978 CHEMBL3156 Thromboxane A2 Receptor, Rat 3
TRPA1_MOUSE Q8BLA8 CHEMBL1075310 Transient Receptor Potential Cation Channel Subfamily A Member 1, Mouse 3
Z100081 Z100081 CHEMBL613107 PBMC (Peripheral Blood Mononuclear Cells) 3
Z50594 Z50594 CHEMBL375 Mus Musculus 3
Z80024 Z80024 CHEMBL614518 A9 (Fibroblast Cells) 3
Z80224 Z80224 CHEMBL387 MCF7 (Breast Carcinoma Cells) 3
Z80566 Z80566 CHEMBL612794 U-937 (Histiocytic Lymphoma Cells) 3
Z80928 Z80928 CHEMBL394 HCT-116 (Colon Carcinoma Cells) 3
5HT1B_HUMAN P28222 CHEMBL1898 Serotonin 1b (5-HT1b) Receptor, Human 2
5HT1F_HUMAN P30939 CHEMBL1805 Serotonin 1f (5-HT1f) Receptor, Human 2
5HT2A_HUMAN P28223 CHEMBL224 Serotonin 2a (5-HT2a) Receptor, Human 2
ACM2_HUMAN P08172 CHEMBL211 Muscarinic Acetylcholine Receptor M2, Human 2
ADA1A_HUMAN P35348 CHEMBL229 Alpha-1a Adrenergic Receptor, Human 2
ADA1A_RABIT O02824 CHEMBL3637 Alpha-1a Adrenergic Receptor, Rabit 2
ADA1B_HUMAN P35368 CHEMBL232 Alpha-1b Adrenergic Receptor, Human 2
ADA1D_HUMAN P25100 CHEMBL223 Alpha-1d Adrenergic Receptor, Human 2
ADA1D_RABIT O02666 CHEMBL4407 Alpha-1d Adrenergic Receptor, Rabit 2
ADA2B_HUMAN P18089 CHEMBL1942 Alpha-2b Adrenergic Receptor, Human 2
AGTRB_RAT P29089 CHEMBL263 Angiotensin II Type 1b (AT-1b) Receptor, Rat 2
BKRB1_RABIT P48748 CHEMBL4087 Bradykinin B1 Receptor, Rabit 2
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 2
DRD4_RAT P30729 CHEMBL3361 Dopamine D4 Receptor, Rat 2
EDNRA_HUMAN P25101 CHEMBL252 Endothelin Receptor ET-A, Human 2
EDNRB_HUMAN P24530 CHEMBL1785 Endothelin Receptor ET-B, Human 2
PDE4B_HUMAN Q07343 CHEMBL275 Phosphodiesterase 4B, Human 2
PDE4D_HUMAN Q08499 CHEMBL288 Phosphodiesterase 4D, Human 2
Q864F1_PIG Q864F1 CHEMBL3634 Phosphodiesterase 5, Pig 2
Z100489 Z100489 CHEMBL614636 Eosinophils (Eosinophils) 2
Z101865 Z101865 CHEMBL612790 Leishmania Chagasi 2
Z50457 Z50457 CHEMBL612877 Leishmania Amazonensis 2
Z50458 Z50458 CHEMBL612878 Leishmania Braziliensis 2
Z50460 Z50460 CHEMBL612879 Leishmania Major 2
Z80026 Z80026 CHEMBL613860 AGS (Gastric Adenocarcinoma Cells) 2
Z80387 Z80387 CHEMBL612556 PC-12 (Adrenal Phaeochromacytoma Cells) 2
Z80902 Z80902 CHEMBL614150 HASMC (Aortic Smooth Muscle Cells) 2
5HT1A_HUMAN P08908 CHEMBL214 Serotonin 1a (5-HT1a) Receptor, Human 1
5HT2B_HUMAN P41595 CHEMBL1833 Serotonin 2b (5-HT2b) Receptor, Human 1
5HT2C_HUMAN P28335 CHEMBL225 Serotonin 2c (5-HT2c) Receptor, Human 1
5HT3A_HUMAN P46098 CHEMBL1899 Serotonin 3a (5-HT3a) Receptor, Human 1
5HT3A_MOUSE P23979 CHEMBL4972 Serotonin 3a (5-HT3a) Receptor, Mouse 1
5HT4R_HUMAN Q13639 CHEMBL1875 Serotonin 4 (5-HT4) Receptor, Human 1
5HT4R_RAT Q62758 CHEMBL4317 Serotonin 4 (5-HT4) Receptor, Rat 1
5HT7R_HUMAN P34969 CHEMBL3155 Serotonin 7 (5-HT7) Receptor, Human 1
AA1R_RAT P25099 CHEMBL318 Adenosine A1 Receptor, Rat 1
AA2AR_RAT P30543 CHEMBL302 Adenosine A2a Receptor, Rat 1
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 1
ABCC8_HUMAN Q09428 CHEMBL2071 Sulfonylurea Receptor 1, Human 1
ABCC9_HUMAN O60706 CHEMBL1971 Sulfonylurea Receptor 2, Human 1
ACM1_RAT P08482 CHEMBL276 Muscarinic Acetylcholine Receptor M1, Rat 1
ACM3_MOUSE Q9ERZ3 CHEMBL5105 Muscarinic Acetylcholine Receptor M3, Mouse 1
ACM3_RAT P08483 CHEMBL320 Muscarinic Acetylcholine Receptor M3, Rat 1
ACM4_RAT P08485 CHEMBL317 Muscarinic Acetylcholine Receptor M4, Rat 1
ADA2B_RAT P19328 CHEMBL266 Alpha-2b Adrenergic Receptor, Rat 1
AGTR1_BOVIN P25104 CHEMBL3374 Angiotensin II Type 1a (AT-1a) Receptor, Bovin 1
AGTR2_RAT P35351 CHEMBL257 Angiotensin II Type 2 (AT-2) Receptor, Rat 1
AGTRA_RAT P25095 CHEMBL329 Angiotensin II Type 1a (AT-1a) Receptor, Rat 1
ARP19_RAT Q712U5 CHEMBL2170 Cyclic AMP Phosphoprotein, Rat 1
CAC1A_RAT P54282 CHEMBL4417 Voltage-gated P/Q-type Calcium Channel Alpha-1A Subunit, Rat 1
CAC1B_RAT Q02294 CHEMBL5107 Voltage-gated N-type Calcium Channel Alpha-1B Subunit, Rat 1
CAC1G_RAT O54898 CHEMBL4257 Voltage-gated T-type Calcium Channel Alpha-1G Subunit, Rat 1
CAC1H_RAT Q9EQ60 CHEMBL5134 Voltage-gated T-type Calcium Channel Alpha-1H Subunit, Rat 1
CAC1I_RAT Q9Z0Y8 CHEMBL5459 Voltage-gated T-type Calcium Channel Alpha-1I Subunit, Rat 1
DRD1_BOVIN Q95136 CHEMBL2967 Dopamine D1 Receptor, Bovin 1
DRD2_BOVIN P20288 CHEMBL3998 Dopamine D2 Receptor, Bovin 1
DRD3_RAT P19020 CHEMBL3138 Dopamine D3 Receptor, Rat 1
DRD5_RAT P25115 CHEMBL2281 Dopamine D5 Receptor, Rat 1
ESR1_HUMAN P03372 CHEMBL206 Estrogen Receptor Alpha, Human 1
ESR2_HUMAN Q92731 CHEMBL242 Estrogen Receptor Beta, Human 1
GCYA1_BOVIN P19687 CHEMBL3915 Guanylate Cyclase Soluble Alpha-1 Chain, Bovin 1
GCYB1_BOVIN P16068 CHEMBL3193 Guanylate Cyclase Soluble Beta-1 Chain, Bovin 1
IRK11_HUMAN Q14654 CHEMBL1886 Potassium Channel, Inwardly Rectifying, Subfamily J, Member 11, Human 1
IRK8_HUMAN Q15842 CHEMBL4770 Potassium Channel, Inwardly Rectifying, Subfamily J, Member 8, Human 1
KCNA5_HUMAN P22460 CHEMBL4306 Voltage-gated Potassium Channel Subunit Kv1.5, Human 1
MDR1_HUMAN P08183 CHEMBL4302 P-glycoprotein 1, Human 1
MDR1_MOUSE P06795 CHEMBL3467 P-glycoprotein 1, Mouse 1
MDR3_MOUSE P21447 CHEMBL2573 P-glycoprotein 3, Mouse 1
P97706_RAT P97706 CHEMBL4957 Sodium Channel Protein Type VI Alpha Subunit, Rat 1
PDE2A_HUMAN O00408 CHEMBL2652 Phosphodiesterase 2A, Human 1
SCN5A_RAT P15389 CHEMBL3866 Sodium Channel Protein Type V Alpha Subunit, Rat 1
TA2R_HUMAN P21731 CHEMBL2069 Thromboxane A2 Receptor, Human 1
THAS_RAT P49430 CHEMBL4028 Thromboxane-A Synthase, Rat 1
Z102178 Z102178 CHEMBL613694 Liver Microsomes 1
Z102222 Z102222 CHEMBL613424 Plasma 1
Z102317 Z102317 CHEMBL613617 Brain 1
Z102352 Z102352 CHEMBL613652 Plasma 1
Z102372 Z102372 CHEMBL613672 Aorta 1
Z102380 Z102380 CHEMBL613680 Ileum 1
Z50347 Z50347 CHEMBL361 Saccharomyces Cerevisiae 1
Z50607 Z50607 CHEMBL378 Human Immunodeficiency Virus 1 1
Z50740 Z50740 CHEMBL612361 Cricetinae Gen. Sp. 1
Z50796 Z50796 CHEMBL614874 Monkey 1
Z80025 Z80025 CHEMBL614519 ACHN (Renal Adenocarcinoma Cells) 1
Z80051 Z80051 CHEMBL614532 C6-BU-1 1
Z80133 Z80133 CHEMBL614294 EMT6 (Mammary Carcinoma Cells) 1
Z80141 Z80141 CHEMBL614571 GH3 (Pituitary Adenoma Cells) 1
Z80232 Z80232 CHEMBL614128 MCF7-VP 1
Z80334 Z80334 CHEMBL613828 NG108-15 (Neuroblastoma-glioma Hybrid Cells) 1
Z80362 Z80362 CHEMBL389 P388 (Lymphoma Cells) 1
Z80364 Z80364 CHEMBL614218 P388/ADR (Lymphoma Cells) 1
Z80390 Z80390 CHEMBL390 PC-3 (Prostate Carcinoma Cells) 1
Z80485 Z80485 CHEMBL614919 SK-MEL-28 (Melanoma Cells) 1
Z80490 Z80490 CHEMBL614923 SK-MES-1 1
Z80532 Z80532 CHEMBL614774 T-24 (Bladder Carcinoma Cells) 1
Z80561 Z80561 CHEMBL615023 U2OS (Osteosarcoma Cells) 1
Z80583 Z80583 CHEMBL391 Vero (Kidney Cells) 1
Z80653 Z80653 CHEMBL613105 9L (Glioma Cells) 1
Z80711 Z80711 CHEMBL613829 NCI/ADR-RES (Breast Carcinoma Cells) 1
Z80773 Z80773 CHEMBL614456 CHRC/5 Cell Line 1
Z80774 Z80774 CHEMBL614457 CHRC5 Cell Line 1
Z80874 Z80874 CHEMBL393 CEM (T-cell Leukemia) 1
Z81008 Z81008 CHEMBL614788 Human Breast Cancer Cell Lines 1
Z81011 Z81011 CHEMBL614840 Human Cell Lines 1
Z81020 Z81020 CHEMBL395 HepG2 (Hepatoblastoma Cells) 1
Z81068 Z81068 CHEMBL614649 Ishikawa (Uterine Carcinoma Cells) 1
Z81072 Z81072 CHEMBL397 Jurkat (Acute Leukemic T-cells) 1
Z81170 Z81170 CHEMBL612518 LNCaP (Prostate Carcinoma) 1
Z81245 Z81245 CHEMBL614697 MDA-MB-435 (Breast Carcinoma Cells) 1
Z81247 Z81247 CHEMBL399 HeLa (Cervical Adenocarcinoma Cells) 1
Z81252 Z81252 CHEMBL400 MDA-MB-231 (Breast Adenocarcinoma Cells) 1
Z81280 Z81280 CHEMBL614740 NCI-H226 (Non-small Cell Lung Carcinoma Cells) 1