UCSF

A-375 (Malignant Melanoma Cells) (97 Compounds)

Swissprot:
Z80018
Stitch:
Z80018
UniProt:
Z80018
ChEMBL:
CHEMBL613859

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Functional ≤ 10μM 97 8 3 3

Reactome Network (0)

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
Z80928 Z80928 CHEMBL394 HCT-116 (Colon Carcinoma Cells) 39
Z81247 Z81247 CHEMBL399 HeLa (Cervical Adenocarcinoma Cells) 38
Z80682 Z80682 CHEMBL392 A549 (Lung Carcinoma Cells) 30
Z80224 Z80224 CHEMBL387 MCF7 (Breast Carcinoma Cells) 26
Z81252 Z81252 CHEMBL400 MDA-MB-231 (Breast Adenocarcinoma Cells) 23
Z80193 Z80193 CHEMBL386 L1210 (Lymphocytic Leukemia Cells) 19
Z80390 Z80390 CHEMBL390 PC-3 (Prostate Carcinoma Cells) 19
Z80354 Z80354 CHEMBL614213 OVCAR-3 (Ovarian Adenocarcinoma Cells) 16
Z81017 Z81017 CHEMBL614647 WiDr (Colon Adenocarcinoma Cells) 16
Z80433 Z80433 CHEMBL614882 RPMI-8226 (Multiple Myeloma Cells) 15
Z80526 Z80526 CHEMBL612544 SW480 (Colon Adenocarcinoma Cells) 14
Z81057 Z81057 CHEMBL613979 HUVEC (Umbilical Vein Endothelial Cells) 14
Z80164 Z80164 CHEMBL614580 HT-1080 (Fibrosarcoma Cells) 13
Z80211 Z80211 CHEMBL614721 LoVo (Colon Adenocarcinoma Cells) 13
Z80712 Z80712 CHEMBL614361 T47D (Breast Carcinoma Cells) 13
Z81024 Z81024 CHEMBL396 NCI-H460 (Non-small Cell Lung Carcinoma) 11
Z80493 Z80493 CHEMBL614925 SK-OV-3 (Ovarian Carcinoma Cells) 10
Z81170 Z81170 CHEMBL612518 LNCaP (Prostate Carcinoma) 10
PGFRB_HUMAN P09619 CHEMBL1913 Platelet-derived Growth Factor Receptor Beta, Human 9
Z100490 Z100490 CHEMBL612588 ASPC1 (Pancreatic Tumour Cell Line) 8
Z80156 Z80156 CHEMBL383 HL-60 (Promyeloblast Leukemia Cells) 8
Z80852 Z80852 CHEMBL614069 A-431 (Epidermoid Carcinoma Cells) 8
Z81335 Z81335 CHEMBL612263 HCT-15 (Colon Adenocarcinoma Cells) 8
Z80064 Z80064 CHEMBL382 CCRF-CEM (T-cell Leukemia) 7
Z80186 Z80186 CHEMBL385 K562 (Erythroleukemia Cells) 7
Z80254 Z80254 CHEMBL614343 MES-SA (Uterine Sarcoma Cells) 7
Z80291 Z80291 CHEMBL614181 MRC5 (Embryonic Lung Fibroblast Cells) 7
Z80101 Z80101 CHEMBL614562 COLO 320DM (Colon Adenocarcinoma Cells) 6
Z80166 Z80166 CHEMBL384 HT-29 (Colon Adenocarcinoma Cells) 6
Z81115 Z81115 CHEMBL398 KB (Squamous Cell Carcinoma) 6
Z80532 Z80532 CHEMBL614774 T-24 (Bladder Carcinoma Cells) 5
Z80902 Z80902 CHEMBL614150 HASMC (Aortic Smooth Muscle Cells) 5
Z80114 Z80114 CHEMBL614281 Daudi (Burkitts Lymphoma Cells) 4
Z80125 Z80125 CHEMBL613508 DU-145 (Prostate Carcinoma) 4
Z80169 Z80169 CHEMBL614039 Huh-7 (Hepatocellular Carcinoma) 4
Z80255 Z80255 CHEMBL613827 MES-SA/DxS (Uterine Sarcoma Cells) 4
Z80269 Z80269 CHEMBL614354 MKN-45 (Gastric Adenocarcinoma Cells) 4
Z80475 Z80475 CHEMBL613834 SK-BR-3 (Breast Adenocarcinoma) 4
Z80485 Z80485 CHEMBL614919 SK-MEL-28 (Melanoma Cells) 4
Z80800 Z80800 CHEMBL614725 MIA PaCa-2 (Pancreatic Carcinoma Cells) 4
Z80999 Z80999 CHEMBL612258 HT-1376 (Bladder Carcinoma Cells) 4
Z100183 Z100183 CHEMBL614949 PA-1 (Ovarian Carcinoma Cells) 3
Z103203 Z103203 CHEMBL1075388 A375 3
Z50587 Z50587 CHEMBL372 Homo Sapiens 3
Z80109 Z80109 CHEMBL614565 CTLL (Cytotoxic T-cells) 3
Z80138 Z80138 CHEMBL614036 G-361 (Melanoma Cells) 3
Z80362 Z80362 CHEMBL389 P388 (Lymphoma Cells) 3
Z80364 Z80364 CHEMBL614218 P388/ADR (Lymphoma Cells) 3
Z80488 Z80488 CHEMBL614922 SK-MEL-5 (Melanoma Cells) 3
Z80768 Z80768 CHEMBL614455 CH1 (Ovarian Carcinoma Cells) 3
Z81020 Z81020 CHEMBL395 HepG2 (Hepatoblastoma Cells) 3
Z81034 Z81034 CHEMBL614004 A2780 (Ovarian Carcinoma Cells) 3
Z81043 Z81043 CHEMBL613969 N592 3
Z81046 Z81046 CHEMBL613972 ST-KM-1 3
Z81245 Z81245 CHEMBL614697 MDA-MB-435 (Breast Carcinoma Cells) 3
Z81261 Z81261 CHEMBL614127 UACC-375 3
Z81339 Z81339 CHEMBL612552 TF-1 (Bone Marrow Erythroleukemic Cells) 3
Z81341 Z81341 CHEMBL614310 Tumor Cell Lines 3
TOP1_HUMAN P11387 CHEMBL1781 DNA Topoisomerase I, Human 2
TOP1_MOUSE Q04750 CHEMBL2814 DNA Topoisomerase I, Mouse 2
TOP2A_HUMAN P11388 CHEMBL1806 DNA Topoisomerase II Alpha, Human 2
TOP2A_MOUSE Q01320 CHEMBL3586 DNA Topoisomerase II Alpha, Mouse 2
TOP2B_HUMAN Q02880 CHEMBL3396 DNA Topoisomerase II Beta, Human 2
TOP2B_MOUSE Q64511 CHEMBL5564 DNA Topoisomerase II Beta, Mouse 2
Z103205 Z103205 CHEMBL1075390 A431 2
Z103219 Z103219 CHEMBL1075404 Ca9-22 2
Z50347 Z50347 CHEMBL361 Saccharomyces Cerevisiae 2
Z50643 Z50643 CHEMBL379 Hepatitis C Virus 2
Z80008 Z80008 CHEMBL612565 5637 (Epithelial Bladder Carcinoma Cells) 2
Z80017 Z80017 CHEMBL614023 A2780cisR (Cisplatin-resistant Ovarian Carcinoma Cells) 2
Z80021 Z80021 CHEMBL614516 A498 (Renal Carcinoma Cells) 2
Z80025 Z80025 CHEMBL614519 ACHN (Renal Adenocarcinoma Cells) 2
Z80026 Z80026 CHEMBL613860 AGS (Gastric Adenocarcinoma Cells) 2
Z80035 Z80035 CHEMBL381 B16 (Melanoma Cells) 2
Z80039 Z80039 CHEMBL614526 BGC-823 (Stomach Adenocarcinoma Cells) 2
Z80045 Z80045 CHEMBL613870 BT-20 (Breast Carcinoma Cells) 2
Z80052 Z80052 CHEMBL614533 C8166 (Leukemic T-cells) 2
Z80054 Z80054 CHEMBL614058 Caco-2 (Colon Adenocarcinoma Cells) 2
Z80068 Z80068 CHEMBL614542 CCRF-SB (Lymphoblastic Leukemia Cells) 2
Z80088 Z80088 CHEMBL613853 CHO (Ovarian Cells) 2
Z80092 Z80092 CHEMBL614031 CHO-K1 (Ovarian Cells) 2
Z80105 Z80105 CHEMBL613854 COR-L23 (Lung Carcinoma Cells) 2
Z80126 Z80126 CHEMBL614289 DuPro 2
Z80145 Z80145 CHEMBL614045 H69 2
Z80175 Z80175 CHEMBL614585 IMR-32 (Neuroblastoma Cells) 2
Z80188 Z80188 CHEMBL614590 KB 3-1 (Cervical Epithelial Carcinoma Cells) 2
Z80214 Z80214 CHEMBL614317 M14 (Melanoma Cells) 2
Z80227 Z80227 CHEMBL614324 MCF7-ADR (Breast Carcinoma Cells) 2
Z80240 Z80240 CHEMBL614129 MDA-MB-361 2
Z80243 Z80243 CHEMBL614334 MDA-MB-453 (Breast Adenocarcinoma Cells) 2
Z80244 Z80244 CHEMBL614335 MDA-MB-468 (Breast Adenocarcinoma) 2
Z80267 Z80267 CHEMBL614352 MKN-1 2
Z80268 Z80268 CHEMBL614353 MKN-28 (Gastric Epithelial Carcinoma Cells) 2
Z80285 Z80285 CHEMBL614177 MOLT-4 (Acute T-lymphoblastic Leukemia Cells) 2
Z80295 Z80295 CHEMBL388 MT4 (Lymphocytes) 2
Z80302 Z80302 CHEMBL614134 NAKAJIMA 2
Z80322 Z80322 CHEMBL614135 NCI-H358 (Lung Carcinama Cells) 2
Z80323 Z80323 CHEMBL613517 NCI-H417 2
Z80329 Z80329 CHEMBL614196 NCI-H84 2
Z80330 Z80330 CHEMBL614197 NCI-N87 2
Z80348 Z80348 CHEMBL613519 NUGC-4 2
Z80367 Z80367 CHEMBL614220 P388/S 2
Z80381 Z80381 CHEMBL614139 PANC-1 (Pancreatic Carcinoma Cells) 2
Z80389 Z80389 CHEMBL614140 PC-14 2
Z80404 Z80404 CHEMBL614242 QG-90 2
Z80405 Z80405 CHEMBL614052 QG-95 2
Z80406 Z80406 CHEMBL614382 QG-96 2
Z80414 Z80414 CHEMBL614628 Raji (B-lymphoblastic Cells) 2
Z80441 Z80441 CHEMBL614889 RXF 944 2
Z80450 Z80450 CHEMBL614895 Sarcoma-180 2
Z80466 Z80466 CHEMBL614907 SF268 2
Z80468 Z80468 CHEMBL614908 SF-295 (Glioblastoma Cells) 2
Z80472 Z80472 CHEMBL612542 SiHa (Cervical Squamous Cell Carcinoma) 2
Z80477 Z80477 CHEMBL614912 SK_HEP1 (Hepatoma Cells) 2
Z80479 Z80479 CHEMBL614914 SK-MEL (Melanoma Cells) 2
Z80481 Z80481 CHEMBL614916 SK-MEL-1 (Metastatic Melanoma Cells) 2
Z80482 Z80482 CHEMBL614917 SK-MEL-2 (Melanoma Cells) 2
Z80490 Z80490 CHEMBL614923 SK-MES-1 2
Z80491 Z80491 CHEMBL614163 SK-N-MC (Neuroepithelioma Cells) 2
Z80492 Z80492 CHEMBL614924 SK-N-SH (Neuroblastoma Cells) 2
Z80495 Z80495 CHEMBL614927 SK-VLB 2
Z80503 Z80503 CHEMBL614931 SNU1 2
Z80509 Z80509 CHEMBL614935 SNU-638 (Gastric Carcinoma Cells) 2
Z80559 Z80559 CHEMBL615021 U251 2
Z80560 Z80560 CHEMBL615022 U-251 (Glioma Cells) 2
Z80563 Z80563 CHEMBL615025 U-373 MG ( Glioblastoma Cells) 2
Z80565 Z80565 CHEMBL614247 U-87 MG (Glioblastoma Cells) 2
Z80574 Z80574 CHEMBL612799 UMUC3 2
Z80581 Z80581 CHEMBL614248 VA13 2
Z80583 Z80583 CHEMBL391 Vero (Kidney Cells) 2
Z80595 Z80595 CHEMBL612810 WIL2-NS (Lymphoblastoid Cells) 2
Z80600 Z80600 CHEMBL613533 XF498 (Glioma Cells) 2
Z80608 Z80608 CHEMBL614393 ZR-75-1 (Breast Carcinoma Cells) 2
Z80661 Z80661 CHEMBL614567 A704 (Renal Carcinoma Cells) 2
Z80697 Z80697 CHEMBL614279 Bel-7402 (Hepatoma Cells) 2
Z80726 Z80726 CHEMBL614367 TRAMP-C1A (Prostate Carcinoma Cells) 2
Z80730 Z80730 CHEMBL614368 C2D Cell Line 2
Z80731 Z80731 CHEMBL613541 C2G Cell Line 2
Z80732 Z80732 CHEMBL614369 TRAMP-C2H (Prostate Carcinoma Cells) 2
Z80735 Z80735 CHEMBL614739 C38 (Colon Carcinoma) 2
Z80784 Z80784 CHEMBL614462 Col2 (Colon Carcinoma Cells) 2
Z80801 Z80801 CHEMBL614151 CRL-7065 Cell Line 2
Z80819 Z80819 CHEMBL614484 J774.2 2
Z80846 Z80846 CHEMBL614493 F460pv8/eto Cell Line 2
Z80855 Z80855 CHEMBL614498 FLS Cell Line 2
Z80874 Z80874 CHEMBL393 CEM (T-cell Leukemia) 2
Z80887 Z80887 CHEMBL614802 H2981 Cell Line 2
Z80889 Z80889 CHEMBL614803 NCI-H322M (Non-small Cell Lung Carcinoma Cells) 2
Z80896 Z80896 CHEMBL614805 NCI-H69 (Small Cell Lung Carcinoma Cells) 2
Z80936 Z80936 CHEMBL614818 HEK293 (Embryonic Kidney Fibroblasts) 2
Z80943 Z80943 CHEMBL614819 HEL 299 2
Z80945 Z80945 CHEMBL614735 HEp-2 (Laryngeal Carcinoma Cells) 2
Z80980 Z80980 CHEMBL614736 HOS (Osteosarcoma Cells) 2
Z81005 Z81005 CHEMBL614839 HTB-54 Cell Line 2
Z81006 Z81006 CHEMBL612259 Human Breast 401NL Tumor Cell Line 2
Z81025 Z81025 CHEMBL613890 Human Lung LXF 529L Tumor Cell Line 2
Z81026 Z81026 CHEMBL614689 Human Lung LXF 629L Tumor Cell Line 2
Z81028 Z81028 CHEMBL613892 Human Melanoma Cell Line 2
Z81054 Z81054 CHEMBL613977 SF-268 (Glioblastoma Cells) 2
Z81072 Z81072 CHEMBL397 Jurkat (Acute Leukemic T-cells) 2
Z81080 Z81080 CHEMBL613991 KATO-III Cell Line 2
Z81101 Z81101 CHEMBL614010 KBM-3 Cell Line 2
Z81102 Z81102 CHEMBL613994 KBM-3/DOX Cell Line 2
Z81120 Z81120 CHEMBL614674 KK-47 Cell Line 2
Z81133 Z81133 CHEMBL614000 L1210 (1565) 2
Z81134 Z81134 CHEMBL614650 L2987 (Lung Adenocarcinoma Cells) 2
Z81160 Z81160 CHEMBL614088 Lewis Lung Carcinoma Cell Line 2
Z81164 Z81164 CHEMBL614091 LL Cell Line 2
Z81167 Z81167 CHEMBL614093 LLTC Cell Line 2
Z81184 Z81184 CHEMBL614096 LOX IMVI (Melanoma Cells) 2
Z81188 Z81188 CHEMBL614694 Lu-65 Cell Line 2
Z81192 Z81192 CHEMBL614101 PC-8 2
Z81193 Z81193 CHEMBL614102 PC-9 2
Z81201 Z81201 CHEMBL614643 HOP-62 (Non-small Cell Lung Carcinoma Cells) 2
Z81204 Z81204 CHEMBL612268 QG-56 2
Z81211 Z81211 CHEMBL614109 LXFL529 Cell Line 2
Z81244 Z81244 CHEMBL614123 J774 (Macrophage Cells) 2
Z81257 Z81257 CHEMBL614732 MEL-AC Cell Line 2
Z81277 Z81277 CHEMBL613287 NCI-N417 2
Z81280 Z81280 CHEMBL614740 NCI-H226 (Non-small Cell Lung Carcinoma Cells) 2
Z81284 Z81284 CHEMBL614999 NCI-H647 2
Z81329 Z81329 CHEMBL614303 STSA-1 Cell Line 2
Z81331 Z81331 CHEMBL612262 SW-620 (Colon Adenocarcinoma Cells) 2
Z100505 Z100505 CHEMBL612591 BUD-8 (Fibroblast Cells) 1
Z100520 Z100520 CHEMBL612598 KHOS/NP (Osteosarcoma Cells) 1
Z100525 Z100525 CHEMBL612579 MAT-Ly-Lu (Prostate Carcinoma Cells) 1
Z101848 Z101848 CHEMBL612780 Human Herpesvirus 8 1
Z103196 Z103196 CHEMBL1075381 22RV1 1
Z50380 Z50380 CHEMBL613088 Mycobacterium Smegmatis 1
Z50425 Z50425 CHEMBL364 Plasmodium Falciparum 1
Z80100 Z80100 CHEMBL614257 COLO 320 (Colon Adenocarcinoma Cells) 1
Z80120 Z80120 CHEMBL614285 DLD-1 (Colon Adenocarcinoma Cells) 1
Z80261 Z80261 CHEMBL614347 MG-63 1
Z80272 Z80272 CHEMBL614048 MKN-74 1
Z80347 Z80347 CHEMBL614208 NUGC-3 (Gastric Carcinoma Cells) 1
Z80386 Z80386 CHEMBL614234 PC10 1
Z80415 Z80415 CHEMBL614629 Ramos (Burkitts Lymhoma B-cells) 1
Z80452 Z80452 CHEMBL614896 SBC-5 1
Z80463 Z80463 CHEMBL614904 SCOV-3 1
Z80525 Z80525 CHEMBL614055 SW48 1
Z80566 Z80566 CHEMBL612794 U-937 (Histiocytic Lymphoma Cells) 1
Z80601 Z80601 CHEMBL614060 XRS6 1
Z80605 Z80605 CHEMBL614251 YMB-1-E 1
Z80640 Z80640 CHEMBL613102 786-0 (Renal Carcinoma Cells) 1
Z80686 Z80686 CHEMBL614274 AZ-521 Cell Line 1
Z81121 Z81121 CHEMBL613996 KKLS Cell Line 1
Z81330 Z81330 CHEMBL614304 SNU- 1

Most Common Rings