| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| July 23rd, 2004 | 15 | Yes |
Popular Name: 2,2':5',2''-Terthiophene 2,2':5',2''-Terthiophene
Find On: PubMed — Wikipedia — Google
CAS Numbers: 1081-34-1 , 825-55-8 , [1081-34-1]
"2,2':5',2''-Terthiophene, 99%"
1081-34-1; C08460; Terthiophene; alpha-Terthienyl
2,2',5',2''-terthienyl; Terthiophene; alpha-Terthienyl; alpha-terthiophene
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 5.00 | -0.47 | -4.37 | 0 | 0 | 0 | 0 | 248.397 | 2 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| Boiling_Point | 160?/0.1mm | Alfa-Aesar |
| Boiling_Point | 160°/0.1mm | Alfa-Aesar |
| Melting_Point | 89-94? | Alfa-Aesar |
| Melting_Point | 89-94° | Alfa-Aesar |
| MP | 95 | TCI |
| Purity | 98% | Fluorochem |
| Patent Database Links | EP1357103; US2005064415; US2006223076 | ChEBI |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| KPCA-4-E | Protein Kinase C Alpha (cluster #4 Of 6), Eukaryotic | Eukaryotes | 10000 | 0.47 | Binding ≤ 10μM |
| KPCB-2-E | Protein Kinase C Beta (cluster #2 Of 4), Eukaryotic | Eukaryotes | 10000 | 0.47 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| KPCA_HUMAN | P17252 | Protein Kinase C Alpha, Human | 10000 | 0.47 | Binding ≤ 10μM |
| KPCB_HUMAN | P05771 | Protein Kinase C Beta, Human | 10000 | 0.47 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Acetylcholine regulates insulin secretion | |
| Activation of NF-kappaB in B cells | |
| Ca2+ pathway | |
| Calmodulin induced events | |
| Depolymerisation of the Nuclear Lamina | |
| Disinhibition of SNARE formation | |
| EGFR Transactivation by Gastrin | |
| G alpha (z) signalling events | |
| HuR stabilizes mRNA | |
| Inactivation, recovery and regulation of the phototransduction cascade | |
| Regulation of KIT signaling | |
| Response to elevated platelet cytosolic Ca2+ | |
| Signaling by SCF-KIT | |
| Syndecan interactions | |
| Trafficking of GluR2-containing AMPA receptors | |
| VEGFR2 mediated cell proliferation | |
| WNT5A-dependent internalization of FZD4 |
