| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| July 23rd, 2004 | 20 | No |
Popular Name: Chloromycetin Chloromycetin
Find On: PubMed — Wikipedia — Google
CAS Numbers: 31342-36-6 , 56-75-7
2,2-dichloro-N-[1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide
31342-36-6; Chloramphenicol pantothenate complex (USAN/INN); D03461; Pantofenicol (TN)
56-75-7; Chloramphenicol; Prestwick_51
CPD000058224; Chloramphenicol; SAM002548963
N1-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-2,2-dichloroacetamide
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 0.73 | 2.74 | -13.52 | 3 | 7 | 0 | 115 | 323.132 | 6 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| Melting_Point | 149-152? | Alfa-Aesar |
| Melting_Point | 149-152° | Alfa-Aesar |
| biological_use | Antibiotic | IBScreen Bioactives |
| Notes | Bacteriostatic antibiotic with activity against gram-positive and gram-negative bacteriaCell culture tested | Apollo Scientific Bioactives |
| PUBCHEM_PATENT_ID | EP0003979A1; EP0011562A1; EP0011716A1; EP0014437A2; EP0020251A2; EP0020251B1; EP0028526A2; EP0056781A2; EP0116718A1; EP0116718B2; EP0120515A2; EP0120516A2; EP0120516B1; EP0126941A2; EP0135532A1; EP0149936A2; EP0173280A1; EP0173280B1; EP0181033A1; EP020445 | IBM Patent Data |
| mechanism | Interferes with transfer of activated aminoacids from soluble RNA to ribosomes | IBScreen Bioactives |
| PUBCHEM_SUBSTANCE_COMMENT | NCC_SAMPLE_SUPPLIER : Enamine; NCC_SUPPLIER_STRUCTURE_ID : 38910502 | NIH Clinical Collection via PubChem |
| mechanism | Protein synthesis inhibitor | IBScreen Bioactives IBScreen Bioactives |
| PUBCHEM_SUBSTANCE_COMMENT | SAMPLE_SUPPLIER: Enamine; SUPPLIER_STRUCTURE_ID: 38910502 | NIH Clinical Collection via PubChem |
