UCSF

ZINC11681777

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.12 -0.78 -35.94 1 3 1 25 297.422 1

Vendor Notes

Note Type Comments Provided By
biological_use Antiemetic used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV) ZereneX Building Blocks
mechanism 5HT(3) receptor antagonist IBScreen Bioactives
biological_use Antiemetic used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV) IBScreen Bioactives

Activity (Go SEA)

Analogs ( Draw Identity 99% 90% 80% 70% )