| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| May 16th, 2008 | 28 | No |
Popular Name: Aztreonam Aztreonam
Find On: PubMed — Wikipedia — Google
CAS Numbers: 78110-38-0 , [78110-38-0]
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | -3.67 | -0.92 | -100.87 | 3 | 13 | -2 | 207 | 433.424 | 7 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| Therapy | antibiotic | SMDC Pharmakon |
| biological_use | Bactericidal antibiotic | IBScreen Bioactives IBScreen Bioactives |
| mechanism | Inhibits mucopeptide synthesis in the bacterial cell wall | IBScreen Bioactives |
| biological_use | Low acute mammalian toxicity | IBScreen Bioactives |
| biological_use | Shows potent and specific activity against gram-negative bacteria and high beta-lactamase stability | IBScreen Bioactives |
| biological_use | Used clinically (e.g. to treat urinary tract infections) | IBScreen Bioactives |
