| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| May 16th, 2008 | 22 | Yes |
(3E)-3-[hydroxy-(pyridin-2-ylamino)methylidene]-2-methyl-1,1-dioxothieno[2,3-e]thiazin-4-one
(3Z)-3-[hydroxy-(pyridin-2-ylamino)methylidene]-2-methyl-1,1-dioxothieno[2,3-e]thiazin-4-one
2H-Thieno(2,3-e)-1,2-thiazine-3-carboxamide, 4-hydroxy-2-methyl-N-2-pyridinyl-, 1,1-dioxide
3-[hydroxy-(pyridin-2-ylamino)methylidene]-2-methyl-1,1-dioxothieno[2,3-e]thiazin-4-one
4-Hydroxy-2-methyl-N-(2-pyridyl)-2H-thieno[2,3-e]-1,2-thiazine-3-carboxamide 1,1-dioxide, 97%
4-hydroxy-2-methyl-N-(pyridin-2-yl)-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide
4-Hydroxy-2-methyl-N-2-pyridinyl-2H-thieno(2,3-e)-1,2-thiazine-3-carboxamide 1,1-dioxide
4-HYDROXY-2-METHYL-N-2-PYRIDINYL-2H-THIENO[2,3-E]-1,2-THIAZINE-3-CARBOXAMIDE 1,1-DIOXIDE
4-Hydroxy-2-methyl-N-2-pyridyl-2H-thieno(2,3-e)-1,2-thiazine-3-carboxamide 1,1-dioxide
4-Hydroxy-2-methyl-N-pyridin-2-yl-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide
59804-37-4; D01767; Tenoxicam (JAN/USAN/INN); Tilcotil (TN)
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 1.94 | 2.62 | -49.11 | 1 | 7 | -1 | 102 | 336.374 | 2 | ↓ |
| Ref Reference (pH 7) | 0.76 | 1.85 | -43.02 | 1 | 7 | -1 | 102 | 336.374 | 2 | ↓ |
| Mid Mid (pH 6-8) | 0.93 | -0.43 | -19.4 | 2 | 7 | 0 | 103 | 337.382 | 1 | ↓ |
| Mid Mid (pH 6-8) | 0.76 | 1.54 | -44.69 | 3 | 7 | 1 | 101 | 338.39 | 2 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| ALOGPS_SOLUBILITY | 2.77e-01 g/l | DrugBank-approved |
| biological_use | Analgesic | IBScreen Bioactives IBScreen Bioactives |
| Indications | anti-inflammatory, NSAID, analgesic | KeyOrganics Bioactives |
| Therapy | antiinflammatory | SMDC Iconix |
| biological_use | Antiinflammatory agent | IBScreen Bioactives |
| Indications | antiinflammatory, NSAID, analgesic | KeyOrganics Bioactives |
| Target | COX | Selleck Chemicals |
| mechanism | Non-selective COX inhibitor | IBScreen Bioactives |
| Target | Others | Selleck Chemicals |
