| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| September 26th, 2005 | 16 | Yes |
Popular Name: Cyclohexyl-9H-adenine Cyclohexyl-9H-adenine
Find On: PubMed — Wikipedia — Google
CAS Number: 4235-94-3
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.21 | -2.37 | -8.63 | 2 | 5 | 0 | 69 | 217.276 | 1 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| P4K2A-2-E | PI4-kinase Type II (cluster #2 Of 2), Eukaryotic | Eukaryotes | 6000 | 0.46 | Binding ≤ 10μM |
| P4K2B-2-E | PI4-kinase Type II Beta (cluster #2 Of 2), Eukaryotic | Eukaryotes | 6000 | 0.46 | Binding ≤ 10μM |
| PI4KA-2-E | PI4-kinase Alpha Subunit (cluster #2 Of 2), Eukaryotic | Eukaryotes | 6000 | 0.46 | Binding ≤ 10μM |
| PI4KB-1-E | PI4-kinase Beta Subunit (cluster #1 Of 2), Eukaryotic | Eukaryotes | 6000 | 0.46 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PI4KA_HUMAN | P42356 | PI4-kinase Alpha Subunit, Human | 3700 | 0.48 | Binding ≤ 10μM |
| PI4KB_HUMAN | Q9UBF8 | PI4-kinase Beta Subunit, Human | 3700 | 0.48 | Binding ≤ 10μM |
| P4K2A_HUMAN | Q9BTU6 | PI4-kinase Type II, Human | 3700 | 0.48 | Binding ≤ 10μM |
| P4K2B_HUMAN | Q8TCG2 | PI4-kinase Type II Beta, Human | 3700 | 0.48 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Synthesis of PIPs at the early endosome membrane | |
| Synthesis of PIPs at the ER membrane | |
| Synthesis of PIPs at the Golgi membrane | |
| Synthesis of PIPs at the plasma membrane |
