UCSF

ZINC13446019

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Substance Information

In ZINC since Heavy atoms Benign functionality
June 19th, 2008 22 Yes

Popular Name: 2-(5-amino-1-benzyl-2-methyl-indol-3-yl)acetamide 2-(5-amino-1-benzyl-2-methyl-ind…

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Download: MOL2 SDF SMILES Flexibase

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.94 5.7 -13.71 4 4 0 74 293.37 4 ↓

Activity (Go SEA)

Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
PA2GA-1-E Phospholipase A2 Group IIA (cluster #1 Of 1), Eukaryotic Eukaryotes 1610 0.37 Functional ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
PA2GA_HUMAN P14555 Phospholipase A2 Group IIA, Human 1610 0.37 Functional ≤ 10μM

Reactome Annotations from Targets (via Uniprot)

Description Species
Acyl chain remodelling of PC
Acyl chain remodelling of PE
Acyl chain remodelling of PG
Acyl chain remodelling of PI
Acyl chain remodelling of PS
Synthesis of PA

Analogs ( Draw Identity 99% 90% 80% 70% )