| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 19th, 2008 | 26 | No |
Popular Name: 3-(1-methylindol-3-yl)-4-(3-nitrophenyl)pyrrole-2,5-dione 3-(1-methylindol-3-yl)-4-(3-nitr…
None
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.32 | 8.91 | -18.13 | 1 | 7 | 0 | 101 | 347.33 | 3 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| KPCG-1-E | Protein Kinase C Gamma (cluster #1 Of 4), Eukaryotic | Eukaryotes | 1900 | 0.31 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| KPCG_RAT | P63319 | Protein Kinase C Gamma, Rat | 1900 | 0.31 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Calmodulin induced events | |
| Disinhibition of SNARE formation | |
| G alpha (z) signalling events | |
| Response to elevated platelet cytosolic Ca2+ | |
| Trafficking of GluR2-containing AMPA receptors | |
| WNT5A-dependent internalization of FZD4 |
