| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 20th, 2008 | 26 | No |
None
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 6.64 | 13.11 | -5.3 | 0 | 2 | 0 | 22 | 373.606 | 12 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| TBB1-2-E | Tubulin Beta-1 Chain (cluster #2 Of 2), Eukaryotic | Eukaryotes | 2100 | 0.31 | Functional ≤ 10μM |
| TBB3-2-E | Tubulin Beta-3 Chain (cluster #2 Of 3), Eukaryotic | Eukaryotes | 2100 | 0.31 | Functional ≤ 10μM |
| TBB4A-2-E | Tubulin Beta-4 Chain (cluster #2 Of 3), Eukaryotic | Eukaryotes | 2100 | 0.31 | Functional ≤ 10μM |
| TBB4B-2-E | Tubulin Beta-2 Chain (cluster #2 Of 3), Eukaryotic | Eukaryotes | 2100 | 0.31 | Functional ≤ 10μM |
| TBB8-2-E | Tubulin Beta-8 Chain (cluster #2 Of 3), Eukaryotic | Eukaryotes | 2100 | 0.31 | Functional ≤ 10μM |
| Z80612-2-O | 2008 (Ovarian Carcinoma Cells) (cluster #2 Of 2), Other | Other | 2100 | 0.31 | Functional ≤ 10μM |
| Z81034-2-O | A2780 (Ovarian Carcinoma Cells) (cluster #2 Of 10), Other | Other | 2100 | 0.31 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| Z80612 | Z80612 | 2008 (Ovarian Carcinoma Cells) | 2100 | 0.31 | Functional ≤ 10μM |
| Z81034 | Z81034 | A2780 (Ovarian Carcinoma Cells) | 2100 | 0.31 | Functional ≤ 10μM |
| TBB1_HUMAN | Q9H4B7 | Tubulin Beta-1 Chain, Human | 2100 | 0.31 | Functional ≤ 10μM |
| TBB4B_HUMAN | P68371 | Tubulin Beta-2 Chain, Human | 2100 | 0.31 | Functional ≤ 10μM |
| TBB3_HUMAN | Q13509 | Tubulin Beta-3 Chain, Human | 2100 | 0.31 | Functional ≤ 10μM |
| TBB4A_HUMAN | P04350 | Tubulin Beta-4 Chain, Human | 2100 | 0.31 | Functional ≤ 10μM |
| TBB8_HUMAN | Q3ZCM7 | Tubulin Beta-8 Chain, Human | 2100 | 0.31 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Formation of tubulin folding intermediates by CCT/TriC | |
| Gap junction assembly | |
| Kinesins | |
| Loss of Nlp from mitotic centrosomes | |
| Loss of proteins required for interphase microtubule organization from the ce | |
| MHC class II antigen presentation | |
| Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane | |
| Mitotic Prometaphase | |
| Post-chaperonin tubulin folding pathway | |
| Prefoldin mediated transfer of substrate to CCT/TriC | |
| Recruitment of mitotic centrosome proteins and complexes | |
| Recruitment of NuMA to mitotic centrosomes | |
| Recycling pathway of L1 | |
| Regulation of PLK1 Activity at G2/M Transition | |
| Resolution of Sister Chromatid Cohesion | |
| Separation of Sister Chromatids | |
| Translocation of GLUT4 to the plasma membrane |
