| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 21st, 2008 | 26 | No |
Popular Name: (E)-1-(6-hydroxy-4,7-dimethoxy-benzofuran-5-yl)-3-(3-methoxyphenyl)prop-2-en-1-one (E)-1-(6-hydroxy-4,7-dimethoxy-b…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.82 | 5.73 | -13 | 1 | 6 | 0 | 78 | 354.358 | 6 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| KCNA1-1-E | Voltage-gated Potassium Channel Subunit Kv1.1 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 2000 | 0.31 | Binding ≤ 10μM |
| KCNA3-1-E | Voltage-gated Potassium Channel Subunit Kv1.3 (cluster #1 Of 3), Eukaryotic | Eukaryotes | 900 | 0.33 | Binding ≤ 10μM |
| Z50587-1-O | Homo Sapiens (cluster #1 Of 9), Other | Other | 1000 | 0.32 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| KCNA3_HUMAN | P22001 | Voltage-gated Potassium Channel Subunit Kv1.3, Human | 800 | 0.33 | Binding ≤ 1μM |
| KCNA1_HUMAN | Q09470 | Voltage-gated Potassium Channel Subunit Kv1.1, Human | 2000 | 0.31 | Binding ≤ 10μM |
| KCNA3_HUMAN | P22001 | Voltage-gated Potassium Channel Subunit Kv1.3, Human | 2000 | 0.31 | Binding ≤ 10μM |
| Z50587 | Z50587 | Homo Sapiens | 1000 | 0.32 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Voltage gated Potassium channels |
