| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 23rd, 2008 | 30 | No |
Popular Name: 4-[(2-chloro-4,5-difluoro-benzoyl)carbamoylamino]-3-(2,2,2-trifluoroethoxy)benzoic 4-[(2-chloro-4,5-difluoro-benzoy…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 4.16 | 7.57 | -56.72 | 2 | 7 | -1 | 108 | 451.711 | 6 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PYGL-1-E | Liver Glycogen Phosphorylase (cluster #1 Of 2), Eukaryotic | Eukaryotes | 450 | 0.30 | Binding ≤ 10μM |
| Z50597-1-O | Rattus Norvegicus (cluster #1 Of 12), Other | Other | 9600 | 0.23 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PYGL_HUMAN | P06737 | Liver Glycogen Phosphorylase, Human | 446.683592 | 0.30 | Binding ≤ 1μM |
| PYGL_HUMAN | P06737 | Liver Glycogen Phosphorylase, Human | 446.683592 | 0.30 | Binding ≤ 10μM |
| Z50597 | Z50597 | Rattus Norvegicus | 9600 | 0.23 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Glycogen breakdown (glycogenolysis) |
