| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 24th, 2008 | 25 | Yes |
Popular Name: 1-(2-hydroxyethoxymethyl)-5-[(3-sec-butoxyphenyl)methyl]pyrimidine-2,4-dione 1-(2-hydroxyethoxymethyl)-5-[(3-…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 1.80 | 3.25 | -20.26 | 2 | 7 | 0 | 94 | 348.399 | 9 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| UPP1-1-E | Uridine Phosphorylase 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 27 | 0.42 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| UPP1_MOUSE | P52624 | Uridine Phosphorylase 1, Mouse | 27 | 0.42 | Binding ≤ 1μM |
| UPP1_MOUSE | P52624 | Uridine Phosphorylase 1, Mouse | 27 | 0.42 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Pyrimidine catabolism | |
| Pyrimidine salvage reactions |
