| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 25th, 2008 | 17 | Yes |
Popular Name: (1S,2S,3S)-2-[(1S)-1-amino-2-hydroxy-2-oxo-ethyl]-3-phenyl-cyclopropane-1-carboxylic (1S,2S,3S)-2-[(1S)-1-amino-2-hyd…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | -1.35 | 4.2 | -93.86 | 3 | 5 | -1 | 108 | 234.231 | 4 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GRM4-1-E | Metabotropic Glutamate Receptor 4 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 7000 | 0.42 | Functional ≤ 10μM |
| GRM6-1-E | Metabotropic Glutamate Receptor 6 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 7000 | 0.42 | Functional ≤ 10μM |
| GRM7-2-E | Metabotropic Glutamate Receptor 7 (cluster #2 Of 2), Eukaryotic | Eukaryotes | 7000 | 0.42 | Functional ≤ 10μM |
| GRM8-1-E | Metabotropic Glutamate Receptor 8 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 7000 | 0.42 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GRM4_RAT | P31423 | Metabotropic Glutamate Receptor 4, Rat | 7000 | 0.42 | Functional ≤ 10μM |
| GRM6_RAT | P35349 | Metabotropic Glutamate Receptor 6, Rat | 7000 | 0.42 | Functional ≤ 10μM |
| GRM7_RAT | P35400 | Metabotropic Glutamate Receptor 7, Rat | 7000 | 0.42 | Functional ≤ 10μM |
| GRM8_RAT | P70579 | Metabotropic Glutamate Receptor 8, Rat | 7000 | 0.42 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Class C/3 (Metabotropic glutamate/pheromone receptors) | |
| G alpha (i) signalling events |
