| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 25th, 2008 | 25 | Yes |
Popular Name: N-[(1S)-1-benzyl-2-dimethylamino-2-oxo-ethyl]-1H-indole-2-carboxamide N-[(1S)-1-benzyl-2-dimethylamino…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.29 | 7.74 | -15.61 | 2 | 5 | 0 | 65 | 335.407 | 5 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PYGL-1-E | Liver Glycogen Phosphorylase (cluster #1 Of 2), Eukaryotic | Eukaryotes | 400 | 0.36 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PYGL_HUMAN | P06737 | Liver Glycogen Phosphorylase, Human | 400 | 0.36 | Binding ≤ 1μM |
| PYGL_HUMAN | P06737 | Liver Glycogen Phosphorylase, Human | 400 | 0.36 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Glycogen breakdown (glycogenolysis) |
