In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
June 26th, 2008 | 34 | Yes |
Popular Name: 2-sec-butyl-3-[[4-[2-(1H-tetrazol-5-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylic 2-sec-butyl-3-[[4-[2-(1H-tetrazo…
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 5.28 | 13.69 | -100.31 | 0 | 8 | -2 | 111 | 450.502 | 7 | ↓ |
Lo Low (pH 4.5-6) | 5.28 | 14.38 | -43.46 | 2 | 8 | 0 | 114 | 452.518 | 7 | ↓ |
Lo Low (pH 4.5-6) | 5.28 | 14.27 | -74.33 | 1 | 8 | -1 | 112 | 451.51 | 7 | ↓ |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
AGTR1-1-E | Type-1 Angiotensin II Receptor (cluster #1 Of 2), Eukaryotic | Eukaryotes | 3900 | 0.22 | Binding ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
AGTR1_BOVIN | P25104 | Angiotensin II Type 1a (AT-1a) Receptor, Bovin | 3900 | 0.22 | Binding ≤ 10μM |
Description | Species |
---|---|
G alpha (q) signalling events | |
Peptide ligand-binding receptors |