| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| November 16th, 2005 | 15 | Yes |
Popular Name: 4-(4-Fluorobenzoyl)piperidine 4-(4-Fluorobenzoyl)piperidine
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CAS Numbers: 132442-43-4 , 25519-78-2 , 56346-57-7 , [56346-57-7]
(4-Fluoro-phenyl)-piperidin-4-yl-methanone hydrochloride
(4-fluorophenyl)(4-piperidyl)methanone hydrochloride
(4-Fluorophenyl)(piperidin-4-yl)methanone
(4-Fluorophenyl)(piperidin-4-yl)methanone hydrochloride
4- (4-Fluorobenzoyl)-piperidine
4-(4'-Fluorobenzoyl)piperidine hydrochloride
4-(4-Fluorobenzoyl)piperidine hydrochloride
4-(4-Fluorobenzoyl)piperidine hydrochloride 97%
4-(4-Fluorobenzoyl)Piperidine Hydrochloride [25519-78-2]
4-(4-Fluorobenzoyl)piperidine hydrochloride, 98%
4-(4-Fluorobenzoyl)piperidine p-toluenesulfonate
4-(4-Fluorobenzoyl)piperidine, HCl
4-(4-fluorobenzoyl)piperidinehydrochloride
4-Fluorophenyl 4-piperidinyl ketone hydrochloride
4-[(4-fluorophenyl)carbonyl]piperidine
4-[(4-fluorophenyl)carbonyl]piperidine hydrochloride
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 1.83 | 5.89 | -47.7 | 2 | 2 | 1 | 34 | 208.256 | 2 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| melting_point | 222 - 224 | KeyOrganics |
| MP | 222-224° | Matrix Scientific |
| purity | 9.500000000000000e+001 | Enamine Building Blocks Enamine Building Blocks |
| Purity | 97% | Fluorochem |
| Purity | 98% | Fluorochem |
| Warnings | IRRITANT, MOISTURE SENSITIVE | Matrix Scientific |
| Warnings | Irritant/Moisture Sensitive | Matrix Scientific |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| 5HT2A-1-E | Serotonin 2a (5-HT2a) Receptor (cluster #1 Of 3), Eukaryotic | Eukaryotes | 430 | 0.59 | Binding ≤ 10μM |
| 5HT2B-2-E | Serotonin 2b (5-HT2b) Receptor (cluster #2 Of 4), Eukaryotic | Eukaryotes | 430 | 0.59 | Binding ≤ 10μM |
| 5HT2C-2-E | Serotonin 2c (5-HT2c) Receptor (cluster #2 Of 3), Eukaryotic | Eukaryotes | 430 | 0.59 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| 5HT2A_RAT | P14842 | Serotonin 2a (5-HT2a) Receptor, Rat | 430 | 0.59 | Binding ≤ 1μM |
| 5HT2B_RAT | P30994 | Serotonin 2b (5-HT2b) Receptor, Rat | 430 | 0.59 | Binding ≤ 1μM |
| 5HT2C_RAT | P08909 | Serotonin 2c (5-HT2c) Receptor, Rat | 430 | 0.59 | Binding ≤ 1μM |
| 5HT2A_RAT | P14842 | Serotonin 2a (5-HT2a) Receptor, Rat | 430 | 0.59 | Binding ≤ 10μM |
| 5HT2B_RAT | P30994 | Serotonin 2b (5-HT2b) Receptor, Rat | 430 | 0.59 | Binding ≤ 10μM |
| 5HT2C_RAT | P08909 | Serotonin 2c (5-HT2c) Receptor, Rat | 1100 | 0.56 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (q) signalling events | |
| Serotonin receptors |
