UCSF

ZINC01482077

Draw Identity 99% 90% 80% 70%

Substance Information

In ZINC since Heavy atoms Benign functionality
August 19th, 2004 37 No

Popular Name: Gliquidone Gliquidone

Find On: PubMed — Wikipedia — Google

CAS Number: 33342-05-1

Other Names:

1-Cyclohexyl-3-((p-(2-(3,4-dihydro-7-methoxy-4,4-dimethyl-1,3-dioxo-2(1H)-isoquinolyl)ethyl)phenyl)sulfonyl)urea

1-Cyclohexyl-3-((p-(2-(3,4-dihydro-7-methoxy-4,4-dimethyl-1,3-dioxo-2(1H)-isoquinolyl)ethyl)phenyl)sulfonyl)urea; 1-Cyclohexyl-3-(p-beta-(4,4-dimethyl-2-methoxy-1,3-(2H,4H)-isoquinolinedione-2-yl)phenethyl)sulfonylurea; 1-cyclohexyl-3-(p-beta-(4,4- dimeth

1-cyclohexyl-3-(p-beta-(4,4- dimethyl-2-methoxy-1,3-(2H,4H)-isoquinolinedione- 2-yl)phenethyl)sulfonylurea

1-Cyclohexyl-3-(p-beta-(4,4-dimethyl-2-methoxy-1,3-(2H,4H)-isoquinolinedione-2-yl)phenethyl)sulfonylurea

1-cyclohexyl-3-[4-[2-(7-methoxy-4,4-dimethyl-1,3-dioxoisoquinolin-2-yl)ethyl]phenyl]sulfonylurea

33342-05-1

33342-05-1; D02430; Gliquidone (INN); Glurenorm (TN)

62783-47-5 (mono-hydrochloride salt)

AB00513989

AC-18847

AC1L3MFD

AKOS001037880

AR-DF 26

ARDF 26

ARDF 26 SE

ARDF-26

Beglynor

Beglynora

Benzenesulfonamide, N-((cyclohexylamino)carbonyl)-4-(2-(3,4-dihydro-7-methoxy-4,4-dimethyl-1,3-dioxo-2(1H)-isoquinolinyl)ethyl)-

Bio-0157

BPBio1_001191

BRD-K80396088-001-03-9

BRN 1559726

BSPBio_001081

C27H33N3O6S

CAS-33342-05-1

CHEMBL383634

CID91610

D02430

DAP000924

DB01251

EINECS 251-463-2

G0332

gli-

glikvidon

Gliquidona

Gliquidona [INN-Spanish]

Gliquidone (BAN

Gliquidone (INN)

Gliquidone [BAN:INN]

Gliquidonum

Gliquidonum [INN-Latin]

Glurenor

Glurenorm

Glurenorm (TN)

glycvidon

HMS1571G03

I06-0185

INN

INN)

LS-159650

LS-159651

LS-31460

MFCD00631870

MI

MI)

MLS000881123

MLS000881174

MLS002154087

MolPort-001-727-724

N-(cyclohexylcarbamoyl)-4-(2-(7-methoxy-4,4-dimethyl-1,3-dioxo-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)benzenesulfonamide

N-[(cyclohexylamino)carbonyl]-4-{2-[4,4-dimethyl-7-(methyloxy)-1,3-dioxo-3,4-dihydroisoquinolin-2(1H)-yl]ethyl}benzenesulfonamide

NCGC00016819-01

NCGC00179315-01

Oprea1_069443

Prestwick0_000991

Prestwick1_000991

Prestwick2_000991

Prestwick3_000991

QA-1505

SMR000685793

SPBio_002972

TL8002523

UNII-C7C2QDD75P

ZINC01482077

Download: MOL2 SDF SMILES Flexibase

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.28 6.41 -65.16 1 9 -1 128 526.635 8 ↓
Ref Reference (pH 7) 3.28 5.86 -21.8 2 9 0 125 527.643 8 ↓
Lo Low (pH 4.5-6) 3.65 8.35 -20.55 2 9 0 122 527.643 7 ↓

Vendor Notes

Note Type Comments Provided By
MP 179 TCI
ALOGPS_SOLUBILITY 2.20e-03 g/l DrugBank-approved
biological_use Antidiabetic agent IBScreen Bioactives
biological_use Antihyperglycaemic agent IBScreen Bioactives IBScreen Bioactives
Target Others Selleck Chemicals
Target Potassium Channel Selleck Chemicals
mechanism Potassium channels ZereneX Building Blocks
mechanism Potassium channels (KATP) blocker IBScreen Bioactives
Indications type II diabetes KeyOrganics Bioactives

Activity (Go SEA)

Analogs ( Draw Identity 99% 90% 80% 70% )

No pre-computed analogs available. Try a structural similarity search.