| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| July 18th, 2008 | 15 | Yes |
Popular Name: ()-LY 367385 ()-LY 367385
Find On: PubMed — Wikipedia — Google
CAS Numbers: 198419-90-8 , 198419-91-9
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | -1.04 | 2.53 | -86.33 | 3 | 5 | -1 | 108 | 208.193 | 3 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GRM1-2-E | Metabotropic Glutamate Receptor 1 (cluster #2 Of 5), Eukaryotic | Eukaryotes | 8800 | 0.47 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GRM1_HUMAN | Q13255 | Metabotropic Glutamate Receptor 1, Human | 8800 | 0.47 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Class C/3 (Metabotropic glutamate/pheromone receptors) | |
| G alpha (q) signalling events |
