UCSF

ZINC00001522

Draw Identity 99% 90% 80% 70%

Substance Information

In ZINC since Heavy atoms Benign functionality
October 28th, 2005 14 No

Popular Name: Guanabenz acetate Guanabenz acetate

Find On: PubMed — Wikipedia — Google

CAS Numbers: 23113-43-1 , 23256-50-0 , 5051-62-7

Other Names:

((2,6-Dichlorobenzylidene)amino)guanidine

nab-

1-{[(2,6-dichlorophenyl)methylidene]amino}guanidine hydrochloride

2,6-Dichlorobenzylideneaminoguanidine

2-((2,6-Dichlorophenyl)methylene)-hydrazinecarboximidamide

2-(2,6-Dichlorobenzylidene)hydrazinecarboximidamide hydrochloride; Guanabenz hydrochloride; Guanoxabenzhydrochloride; Hydrazinecarboximidamide, 2-(2,6-dichlorobenzylidene)-, hydrochloride; LS-76641; WY-8678 hydrochloride

2-[(E)-(2,6-dichlorophenyl)methylideneamino]guanidine

23256-50-0 (monoacetate)

23256-50-0; D00605; Guanabenz acetate (JP16/USP); Wytensin (TN)

23256-50-0; Guanabenz acetate; Prestwick_957

5051-62-7

5051-62-7; C07034; Guanabenz

5051-62-7; D04375; Guanabenz (USAN/INN)

AC1NWAN0

AC1Q3P2X

AR-1J2045

BPBio1_000058

BR-750

BRD-K67847053-015-08-8

BSPBio_000052

C07034

C8H8Cl2N4

CHEBI:101202

CHEMBL420

CID5702063

D04375

DAP000232

DB00629

EINECS 225-750-8

FDA

GBZ

GBZ; Wy-8678; Wy 8678 base; [(2,6-Dichlorobenzylidene)amino]guanidine; N-(2,6-Dichlorobenzylidene)-N'-amidinohydrazine

guan-

Guanabenz

Guanabenz (Acetate)

Guanabenz (hydrochloride)

Guanabenz (INN

Guanabenz (USAN/INN)

Guanabenz (WY-8678) Acetate

Guanabenz Acetate

Guanabenz acetate salt

Guanabenz monoacetate

Guanabenz [USAN:INN]

Guanabenz(USAN)

Guanabenzo

Guanabenzo [INN-Spanish]

Guanabenzum

Guanabenzum [INN-Latin]

Guanidine, ((2,6-dichlorobenzylidene)amino)-

Guanidine, ((2,6-dichlorobenzylidene)amino)- (8CI)

Guanidine, [(2,6-dichlorobenzylidene)amino]-

HMS2089G13

Hydrazinecarboximidamide, 2-((2,6-dichlorophenyl)methylene)-

Hydrazinecarboximidamide, 2-[(2,6-dichlorophenyl)methylene]-

JAN

L000834

LS-175166

LS-187161

MFCD00027408

MFCD00153801

MFCD01722581

MolPort-001-835-432

N-((2,6-Dichlorobenzylidene)amino)guanidine

N-(2,6-Dichlorobenzylidene)-N'-amidinohydrazine

N/A

NCGC00024846-02

NCGC00024846-03

NCGC00024846-04

NCGC00024846-05

NSC-68982

NSC68982

Prestwick2_000096

Prestwick3_000096

T6332738

USAN

USAN)

USAN); Guanabenz Acetate (FDA

USAN); Guanabenz Acetate (JAN

USP

USP)

Wy 8678

Wy 8678 base

WY-8678

WY-8678 acetate

WY-8678; WY-8678 Acetate

Wytensin

[(2,6-Dichlorobenzylidene)amino]guanidine

Download: MOL2 SDF SMILES Flexibase

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.40 5.45 -28.14 5 4 1 76 232.094 3 ↓

Vendor Notes

Note Type Comments Provided By
MP 219 - 221 Enamine Building Blocks
MP 219...221 Enamine Building Blocks
purity 9.500000000000000e+001 Enamine Building Blocks Enamine Building Blocks
Purity 98% Fluorochem
Target Adrenergic Receptor Selleck Chemicals
Indications antihypertensive KeyOrganics Bioactives
Therapy Centrally acting alpha2 adrenoceptor agonist; antihypertensive SMDC Iconix

Activity (Go SEA)

Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
Z50425-9-O Plasmodium Falciparum (cluster #9 Of 22), Other Other 3162 0.55 Functional ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
Z50425 Z50425 Plasmodium Falciparum 10000 0.50 Functional ≤ 10μM

Analogs ( Draw Identity 99% 90% 80% 70% )