UCSF

ZINC01550030

Draw Identity 99% 90% 80% 70%

Substance Information

In ZINC since Heavy atoms Benign functionality
October 6th, 2004 20 Yes

Popular Name: Guanosine Guanosine

Find On: PubMed — Wikipedia — Google

CAS Numbers: 1143525-19-2 , 118-00-3 , 26578-09-6 , [118-00-3] , [26578-09-6]

Other Names:

"Guanosine, 98%"

β-D-ribofuranosyl-6H-purin-6-one; β-D-ribofuranosyl-9H-purin-6(1H)-one; 2-Amino-1,9-dihydro-9-β 2-Amino-1,9-dihydro-9-b-D-ribofuranosyl-6H-purin-6-one; 2-Amino-1,9-dihydro-9beta-d-ribofuranosyl-6H-purin-6-one; 2-amino-9-beta-D-ribofuranosyl

118-00-3; C00387; Guanosine

118-00-3; guanosine; nucleoside Q

2(3H)-imino-9-beta-D-ribofuranosyl-9H-purin-6(1H)-one; 2-amino-1,9-dihydro-9-beta-D-ribofuranosyl-6H-purin-6-one; 2-amino-9-beta-D-ribofuranosyl-1,9-dihydro-6H-purin-6-one; 9-beta-D-ribofuranosyl-guanine; G; Guanine riboside; Guanine-9-beta-D-ribofuranosi

2(3H)-Imino-9-beta-D-ribofuranosyl-9H-purin-6(1H)-one; 2-Amino-1,9-dihydro-9-beta-D-ribofuranosyl-6H-purin-6-one; 6H-Purin-6-one, 2-amino-1,9-dihydro-9-beta-D-ribofuranosyl-; 9-beta-D-Ribofuranosylguanine; AI3-52065; EINECS 204-227-8; GR; GUANINE-9:BETA-D

2(3H)-Imino-9-beta-D-ribofuranosyl-9H-purin-6(1H)-one; 2-Amino-1,9-dihydro-9-beta-D-ribofuranosyl-6H-purin-6-one; 6H-Purin-6-one, 2-amino-1,9-dihydro-9-beta-D-ribofuranosyl-; 9-beta-D-Ribofuranosylguanine; GR; GUANINE-9:BETA-D-RIBOFURANOSIDE; GUANOSINE; G

2-Amino-1,9-dihydro-9-b-D-ribofuranosyl-6H-purin-6-one; 2-Amino-1,9-dihydro-9-beta-delta-ribofuranosyl-6H-purin-6-one; 2-amino-Inosine; 9-b-D-ribofuranosyl-Guanine; 9-beta-delta-ribofuranosyl-Guanine; b-D-Ribofuranoside guanine-9; beta-delta-Ribofuranosid

2-Amino-1,9-dihydro-9-b-D-ribofuranosyl-6H-purin-6-one; 2-Amino-1,9-dihydro-9-beta-delta-ribofuranosyl-6H-purin-6-one; 2-Amino-Inosine; 9-b-D-Ribofuranosyl-Guanine; 9-beta-delta-Ribofuranosyl-Guanine; Guanosine; Ribonucleoside; Vernine; b-D-Ribofuranoside

2-Amino-1,9-dihydro-9-b-D-ribofuranosyl-6H-purin-6-one;2-Amino-1,9-dihydro-9-beta-delta-ribofuranosyl-6H-purin-6-one;2-Amino-Inosine;9-b-D-Ribofuranosyl-Guanine;9-beta-delta-Ribofuranosyl-Guanine;b-D-Ribofuranoside guanine-9;beta-delta-Ribofuranoside guan

2-Amino-1,9-dihydro-9-b-D-ribofuranosyl-6H-purin-6-one;2-Amino-1,9-dihydro-9-beta-delta-ribofuranosyl-6H-purin-6-one;2-Amino-Inosine;9-b-D-Ribofuranosyl-Guanine;9-beta-delta-Ribofuranosyl-Guanine;Guanosine;Ribonucleoside;Vernine;b-D-Ribofuranoside guanine

2-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one

2-Amino-9-beta-D-ribofuranosyl-9H-purine-6- -onehydrate

2-Amino-9-beta-D-ribofuranosyl-9H-purine-6-(1H)-one

2-Amino-9-beta-D-ribofuranosyl-9H-purine-6-(1H)-one hydrate

2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one

CHEBI:471737; CHEBI:42840; CHEBI:5564; CHEBI:42847; CHEBI:42853; CHEBI:24444; CHEBI:14375

Guanosine Hydrate

Guanosine, 98+%

Guanosine, 99%

L-Guanosine

L-Guanosine, 95%+

MFCD00010182

N/A

Download: MOL2 SDF SMILES Flexibase

Annotations

Vendors

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -2.02 -5.03 -22.37 6 10 0 160 283.244 2 ↓

Vendor Notes

Note Type Comments Provided By
Mp [°C] 250 Acros Organics
MP 250° (dec.) Oakwood Chemical
UniProt Database Links 5N3BA_XENLA; 5N3BB_XENLA; 5NT3B_CHICK; 5NT3B_DROME; 5NT3B_HUMAN; 5NT3B_MOUSE; 5NT3B_RAT; ALGD_AZOVI; ALGD_PSEAE; ALGD_PSEPK; ALGD_PSESH; ALGD_PSESM; ALGD_PSESY; ANKX_LEGPH; CDGBP_PSEAE; CMTR2_HUMAN; CMTR2_MOUSE; CMTR2_PONAB; CNCG_BOVIN; CNCG_HUMAN; CNCG_M ChEBI
purity 9.500000000000000e+001 Enamine Building Blocks Enamine Building Blocks
Purity 95% Fluorochem
Melting_Point ca 250? dec. Alfa-Aesar
Melting_Point ca 250° dec. Alfa-Aesar
PUBCHEM_PATENT_ID EP0453597B1; EP0464112A1; EP0464112B1; EP0651759A1; EP0672122A1; EP0673783A2; EP0673783B1; EP0743573A3; EP0743573B1; EP0743574A3; EP0743574B1; EP0827960A1; EP0832211A1; EP0832214A2; EP0832214B1; EP0833902A2; EP0886641A2; EP0896629A1; EP0934331A2; EP096177 IBM Patent Data
Patent Database Links EP0827960; EP1536008; EP1800675; EP1840132; EP1930340; US2001025052; US2003166619; US2004014720; US2004180863; US2005020826; US2005288260; US2007184068; US2007224210; US2007225203; US2007237781; US2007238678; US2007264241; US2007265224; US2007269406; US20 ChEBI
H phrase H301: Toxic if swallowed Acros Organics
Target Others Selleck Chemicals
P phrase P264: Wash face, hands and any exposed skin thoroughly after handling; P301 + P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician Acros Organics
R phrase R25: Toxic if swallowed. Acros Organics
Reactome Database Links REACT_1040; REACT_1054; REACT_1268; REACT_1336; REACT_1504; REACT_1972; REACT_2011; REACT_2012; REACT_22212; REACT_22395; REACT_758; REACT_806; REACT_849; REACT_958 ChEBI
S phrase S24/25: Avoid contact with skin and eyes. Acros Organics
Hazard T: Toxic Acros Organics

Activity (Go SEA)

Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
Z80583-7-O Vero (Kidney Cells) (cluster #7 Of 7), Other Other 30 0.53 Functional ≤ 10μM
Z81338-1-O T-cells (cluster #1 Of 3), Other Other 100 0.49 Functional ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
Z81338 Z81338 T-cells 100 0.49 Functional ≤ 10μM
Z80583 Z80583 Vero (Kidney Cells) 30 0.53 Functional ≤ 10μM

Direct Reactome Annotations (via ChEBI)

Description Species
Purine catabolism
Purine salvage
Transport of nucleosides and free purine and pyrimidine bases across the plasma

Analogs ( Draw Identity 99% 90% 80% 70% )