In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
October 7th, 2004 | 19 | Yes |
Popular Name: 1-benzyl-1H-indole-2-carboxylic acid 1-benzyl-1H-indole-2-carboxylic …
Find On: PubMed — Wikipedia — Google
CAS Numbers: 17017-71-9 , [17017-71-9]
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 3.63 | 1.51 | -51.17 | 0 | 3 | -1 | 45 | 250.277 | 3 | ↓ |
Note Type | Comments | Provided By |
---|---|---|
MP | 197 - 199 | Enamine Building Blocks |
MP | 197...199 | Enamine Building Blocks |
purity | 9.500000000000000e+001 | Enamine Building Blocks Enamine Building Blocks |
Warnings | IRRITANT | Matrix Scientific |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
CCR2-1-E | C-C Chemokine Receptor Type 2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1700 | 0.43 | Binding ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
CCR2_HUMAN | P41597 | C-C Chemokine Receptor Type 2, Human | 1700 | 0.43 | Binding ≤ 10μM |
Description | Species |
---|---|
Beta defensins | |
Chemokine receptors bind chemokines | |
G alpha (i) signalling events |