| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| November 4th, 2005 | 16 | No |
Popular Name: 5-[(4-methoxyphenyl)methylene]thiazolidine-2,4-dione 5-[(4-methoxyphenyl)methylene]th…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 1.54 | 2.31 | -8.34 | 1 | 4 | 0 | 59 | 235.264 | 2 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PIM1-1-E | Serine/threonine-protein Kinase PIM1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 5100 | 0.46 | Binding ≤ 10μM |
| PIM2-1-E | Serine/threonine-protein Kinase PIM2 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 300 | 0.57 | Binding ≤ 10μM |
| Z80418-2-O | RAW264.7 (Monocytic-macrophage Leukemia Cells) (cluster #2 Of 9), Other | Other | 720 | 0.54 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PIM2_HUMAN | Q9P1W9 | Serine/threonine-protein Kinase PIM2, Human | 300 | 0.57 | Binding ≤ 1μM |
| PIM1_HUMAN | P11309 | Serine/threonine-protein Kinase PIM1, Human | 5100 | 0.46 | Binding ≤ 10μM |
| PIM2_HUMAN | Q9P1W9 | Serine/threonine-protein Kinase PIM2, Human | 300 | 0.57 | Binding ≤ 10μM |
| Z80418 | Z80418 | RAW264.7 (Monocytic-macrophage Leukemia Cells) | 720 | 0.54 | Functional ≤ 10μM |
