| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 14th, 2008 | 32 | No |
Popular Name: SU14813 (maleate) SU14813 (maleate)
Find On: PubMed — Wikipedia — Google
CAS Numbers: 627908-92-3 , 849643-15-8
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 0.40 | 1.96 | -15.81 | 4 | 8 | 0 | 110 | 442.491 | 6 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| AAK1-1-E | Adaptor-associated Kinase (cluster #1 Of 2), Eukaryotic | Eukaryotes | 66 | 0.31 | Binding ≤ 10μM |
| AAPK1-1-E | AMP-activated Protein Kinase, Alpha-1 Subunit (cluster #1 Of 1), Eukaryotic | Eukaryotes | 100 | 0.31 | Binding ≤ 10μM |
| AAPK2-1-E | AMP-activated Protein Kinase, Alpha-2 Subunit (cluster #1 Of 1), Eukaryotic | Eukaryotes | 290 | 0.29 | Binding ≤ 10μM |
| ABL1-1-E | Tyrosine-protein Kinase ABL (cluster #1 Of 1), Eukaryotic | Eukaryotes | 970 | 0.26 | Binding ≤ 10μM |
| ACK1-1-E | Tyrosine Kinase Non-receptor Protein 2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 4900 | 0.23 | Binding ≤ 10μM |
| ALK-1-E | ALK Tyrosine Kinase Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 490 | 0.28 | Binding ≤ 10μM |
| ANKK1-1-E | Ankyrin Repeat And Protein Kinase Domain-containing Protein 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 160 | 0.30 | Binding ≤ 10μM |
| AURKB-1-E | Serine/threonine-protein Kinase Aurora-B (cluster #1 Of 2), Eukaryotic | Eukaryotes | 340 | 0.28 | Binding ≤ 10μM |
| AURKC-1-E | Serine/threonine-protein Kinase Aurora-C (cluster #1 Of 2), Eukaryotic | Eukaryotes | 810 | 0.27 | Binding ≤ 10μM |
| BLK-1-E | Tyrosine-protein Kinase BLK (cluster #1 Of 1), Eukaryotic | Eukaryotes | 750 | 0.27 | Binding ≤ 10μM |
| BMP2K-1-E | BMP-2-inducible Protein Kinase (cluster #1 Of 2), Eukaryotic | Eukaryotes | 27 | 0.33 | Binding ≤ 10μM |
| BMPR2-1-E | Bone Morphogenetic Protein Receptor Type-2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 200 | 0.29 | Binding ≤ 10μM |
| BRSK1-1-E | BR Serine/threonine-protein Kinase 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 5000 | 0.23 | Binding ≤ 10μM |
| BRSK2-1-E | BR Serine/threonine-protein Kinase 2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 4100 | 0.24 | Binding ≤ 10μM |
| CDK16-1-E | Serine/threonine-protein Kinase PCTAIRE-1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 940 | 0.26 | Binding ≤ 10μM |
| CDK7-1-E | Cyclin-dependent Kinase 7 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 930 | 0.26 | Binding ≤ 10μM |
| CHK1-1-E | Serine/threonine-protein Kinase Chk1 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 1200 | 0.26 | Binding ≤ 10μM |
| CLK1-1-E | Dual Specificty Protein Kinase CLK1 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 360 | 0.28 | Binding ≤ 10μM |
| CLK2-1-E | Dual Specificity Protein Kinase CLK2 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 150 | 0.30 | Binding ≤ 10μM |
| CLK4-1-E | Dual Specificity Protein Kinase CLK4 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 250 | 0.29 | Binding ≤ 10μM |
| CSF1R-1-E | Macrophage Colony-stimulating Factor 1 Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 4 | 0.37 | Binding ≤ 10μM |
| CSK21-1-E | Casein Kinase II Alpha (cluster #1 Of 3), Eukaryotic | Eukaryotes | 97 | 0.31 | Binding ≤ 10μM |
| CSK22-1-E | Casein Kinase II Alpha (prime) (cluster #1 Of 2), Eukaryotic | Eukaryotes | 140 | 0.30 | Binding ≤ 10μM |
| CTRO-1-E | Citron Rho-interacting Kinase (cluster #1 Of 1), Eukaryotic | Eukaryotes | 94 | 0.31 | Binding ≤ 10μM |
| DAPK1-1-E | Death-associated Protein Kinase 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 270 | 0.29 | Binding ≤ 10μM |
| DAPK2-1-E | Death-associated Protein Kinase 2 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 400 | 0.28 | Binding ≤ 10μM |
| DAPK3-1-E | Death-associated Protein Kinase 3 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 560 | 0.27 | Binding ≤ 10μM |
| DCLK1-1-E | Serine/threonine-protein Kinase DCLK1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 550 | 0.27 | Binding ≤ 10μM |
| DCLK3-1-E | Serine/threonine-protein Kinase DCLK3 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 240 | 0.29 | Binding ≤ 10μM |
| DYR1B-1-E | Dual Specificity Tyrosine-phosphorylation-regulated Kinase 1B (cluster #1 Of 1), Eukaryotic | Eukaryotes | 2600 | 0.24 | Binding ≤ 10μM |
| E2AK2-1-E | Interferon-induced, Double-stranded RNA-activated Protein Kinase (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1300 | 0.26 | Binding ≤ 10μM |
| E2AK4-1-E | Eukaryotic Translation Initiation Factor 2-alpha Kinase 4 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 470 | 0.28 | Binding ≤ 10μM |
| EGFR-1-E | Epidermal Growth Factor Receptor ErbB1 (cluster #1 Of 4), Eukaryotic | Eukaryotes | 9000 | 0.22 | Binding ≤ 10μM |
| EPHA6-1-E | Ephrin Type-A Receptor 6 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 2000 | 0.25 | Binding ≤ 10μM |
| FAK1-1-E | Focal Adhesion Kinase 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1200 | 0.26 | Binding ≤ 10μM |
| FAK2-1-E | Protein-tyrosine Kinase 2-beta (cluster #1 Of 1), Eukaryotic | Eukaryotes | 600 | 0.27 | Binding ≤ 10μM |
| FER-1-E | Tyrosine-protein Kinase FER (cluster #1 Of 1), Eukaryotic | Eukaryotes | 34 | 0.33 | Binding ≤ 10μM |
| FGFR1-1-E | Fibroblast Growth Factor Receptor 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1900 | 0.25 | Binding ≤ 10μM |
| FGFR2-1-E | Fibroblast Growth Factor Receptor 2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 790 | 0.27 | Binding ≤ 10μM |
| FGFR3-1-E | Fibroblast Growth Factor Receptor 3 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 560 | 0.27 | Binding ≤ 10μM |
| FGR-1-E | Tyrosine-protein Kinase FGR (cluster #1 Of 2), Eukaryotic | Eukaryotes | 390 | 0.28 | Binding ≤ 10μM |
| FLT3-1-E | Tyrosine-protein Kinase Receptor FLT3 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 6 | 0.36 | Binding ≤ 10μM |
| FYN-1-E | Tyrosine-protein Kinase FYN (cluster #1 Of 5), Eukaryotic | Eukaryotes | 2600 | 0.24 | Binding ≤ 10μM |
| GAK-1-E | Serine/threonine-protein Kinase GAK (cluster #1 Of 2), Eukaryotic | Eukaryotes | 44 | 0.32 | Binding ≤ 10μM |
| HCK-1-E | Tyrosine-protein Kinase HCK (cluster #1 Of 1), Eukaryotic | Eukaryotes | 2200 | 0.25 | Binding ≤ 10μM |
| IKKE-1-E | Inhibitor Of Nuclear Factor Kappa B Kinase Epsilon Subunit (cluster #1 Of 1), Eukaryotic | Eukaryotes | 480 | 0.28 | Binding ≤ 10μM |
| INSR-1-E | Insulin Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1200 | 0.26 | Binding ≤ 10μM |
| INSRR-1-E | Insulin Receptor-related Protein (cluster #1 Of 1), Eukaryotic | Eukaryotes | 2000 | 0.25 | Binding ≤ 10μM |
| IRAK3-1-E | Interleukin-1 Receptor-associated Kinase 3 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1900 | 0.25 | Binding ≤ 10μM |
| ITK-1-E | Tyrosine-protein Kinase ITK/TSK (cluster #1 Of 1), Eukaryotic | Eukaryotes | 190 | 0.29 | Binding ≤ 10μM |
| JAK1-1-E | Tyrosine-protein Kinase JAK1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 97 | 0.31 | Binding ≤ 10μM |
| JAK2-1-E | Tyrosine-protein Kinase JAK2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1600 | 0.25 | Binding ≤ 10μM |
| JAK3-1-E | Tyrosine-protein Kinase JAK3 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 580 | 0.27 | Binding ≤ 10μM |
| KC1AL-1-E | Casein Kinase I Isoform Alpha-like (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1500 | 0.25 | Binding ≤ 10μM |
| KC1D-1-E | Casein Kinase I Delta (cluster #1 Of 1), Eukaryotic | Eukaryotes | 260 | 0.29 | Binding ≤ 10μM |
| KC1E-1-E | Casein Kinase I Epsilon (cluster #1 Of 2), Eukaryotic | Eukaryotes | 340 | 0.28 | Binding ≤ 10μM |
| KC1G1-1-E | Casein Kinase I Gamma 1 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 1000 | 0.26 | Binding ≤ 10μM |
| KC1G2-1-E | Casein Kinase I Gamma 2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 790 | 0.27 | Binding ≤ 10μM |
| KC1G3-1-E | Casein Kinase I Isoform Gamma-3 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 570 | 0.27 | Binding ≤ 10μM |
| KCC1A-1-E | CaM Kinase I Alpha (cluster #1 Of 2), Eukaryotic | Eukaryotes | 3300 | 0.24 | Binding ≤ 10μM |
| KCC1D-1-E | CaM Kinase I Delta (cluster #1 Of 2), Eukaryotic | Eukaryotes | 970 | 0.26 | Binding ≤ 10μM |
| KCC1G-1-E | CaM Kinase I Gamma (cluster #1 Of 2), Eukaryotic | Eukaryotes | 940 | 0.26 | Binding ≤ 10μM |
| KCC2A-1-E | CaM Kinase II Alpha (cluster #1 Of 1), Eukaryotic | Eukaryotes | 350 | 0.28 | Binding ≤ 10μM |
| KCC2B-1-E | CaM Kinase II Beta (cluster #1 Of 1), Eukaryotic | Eukaryotes | 2300 | 0.25 | Binding ≤ 10μM |
| KCC2D-1-E | CaM Kinase II Delta (cluster #1 Of 1), Eukaryotic | Eukaryotes | 760 | 0.27 | Binding ≤ 10μM |
| KCC2G-1-E | CaM Kinase II Gamma (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1100 | 0.26 | Binding ≤ 10μM |
| KCC4-1-E | CaM Kinase IV (cluster #1 Of 1), Eukaryotic | Eukaryotes | 2700 | 0.24 | Binding ≤ 10μM |
| KIT-1-E | Stem Cell Growth Factor Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1 | 0.39 | Binding ≤ 10μM |
| KIT-1-E | Stem Cell Growth Factor Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 340 | 0.28 | Binding ≤ 10μM |
| KKCC1-1-E | CaM-kinase Kinase Alpha (cluster #1 Of 1), Eukaryotic | Eukaryotes | 850 | 0.27 | Binding ≤ 10μM |
| KKCC2-1-E | CaM-kinase Kinase Beta (cluster #1 Of 2), Eukaryotic | Eukaryotes | 2500 | 0.25 | Binding ≤ 10μM |
| KPCD1-1-E | Protein Kinase C Mu (cluster #1 Of 3), Eukaryotic | Eukaryotes | 2400 | 0.25 | Binding ≤ 10μM |
| KPCD2-1-E | Serine/threonine-protein Kinase D2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 3700 | 0.24 | Binding ≤ 10μM |
| KPCD3-1-E | Protein Kinase C Nu (cluster #1 Of 3), Eukaryotic | Eukaryotes | 2700 | 0.24 | Binding ≤ 10μM |
| KPCT-1-E | Protein Kinase C Theta (cluster #1 Of 3), Eukaryotic | Eukaryotes | 7200 | 0.22 | Binding ≤ 10μM |
| KS6A1-1-E | Ribosomal Protein S6 Kinase Alpha 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 5800 | 0.23 | Binding ≤ 10μM |
| KS6A2-1-E | Ribosomal Protein S6 Kinase Alpha 2 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 9600 | 0.22 | Binding ≤ 10μM |
| KS6A3-1-E | Ribosomal Protein S6 Kinase Alpha 3 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 2100 | 0.25 | Binding ≤ 10μM |
| KS6A4-1-E | Ribosomal Protein S6 Kinase Alpha 4 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 2000 | 0.25 | Binding ≤ 10μM |
| KS6A5-1-E | Ribosomal Protein S6 Kinase Alpha 5 (cluster #1 Of 3), Eukaryotic | Eukaryotes | 1500 | 0.25 | Binding ≤ 10μM |
| KS6A6-1-E | Ribosomal Protein S6 Kinase Alpha 6 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 3100 | 0.24 | Binding ≤ 10μM |
| LATS1-1-E | Serine/threonine-protein Kinase LATS1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 850 | 0.27 | Binding ≤ 10μM |
| LATS2-1-E | Serine/threonine-protein Kinase LATS2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 430 | 0.28 | Binding ≤ 10μM |
| LCK-1-E | Tyrosine-protein Kinase LCK (cluster #1 Of 4), Eukaryotic | Eukaryotes | 2300 | 0.25 | Binding ≤ 10μM |
| LTK-1-E | Leukocyte Tyrosine Kinase Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 4200 | 0.24 | Binding ≤ 10μM |
| LYN-1-E | Tyrosine-protein Kinase Lyn (cluster #1 Of 1), Eukaryotic | Eukaryotes | 810 | 0.27 | Binding ≤ 10μM |
| M3K11-1-E | Mitogen-activated Protein Kinase Kinase Kinase 11 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1700 | 0.25 | Binding ≤ 10μM |
| M3K9-1-E | Mitogen-activated Protein Kinase Kinase Kinase 9 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 2600 | 0.24 | Binding ≤ 10μM |
| M4K1-1-E | Mitogen-activated Protein Kinase Kinase Kinase Kinase 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 15 | 0.34 | Binding ≤ 10μM |
| M4K3-1-E | Mitogen-activated Protein Kinase Kinase Kinase Kinase 3 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 210 | 0.29 | Binding ≤ 10μM |
| M4K4-1-E | Mitogen-activated Protein Kinase Kinase Kinase Kinase 4 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 260 | 0.29 | Binding ≤ 10μM |
| M4K5-1-E | Mitogen-activated Protein Kinase Kinase Kinase Kinase 5 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 300 | 0.29 | Binding ≤ 10μM |
| MARK1-1-E | Serine/threonine-protein Kinase MARK1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1500 | 0.25 | Binding ≤ 10μM |
| MARK2-1-E | MAP/microtubule Affinity-regulating Kinase 2 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 440 | 0.28 | Binding ≤ 10μM |
| MARK3-1-E | Serine/threonine-protein Kinase C-TAK1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1100 | 0.26 | Binding ≤ 10μM |
| MARK4-1-E | MAP/microtubule Affinity-regulating Kinase 4 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 2000 | 0.25 | Binding ≤ 10μM |
| MELK-1-E | Maternal Embryonic Leucine Zipper Kinase (cluster #1 Of 1), Eukaryotic | Eukaryotes | 340 | 0.28 | Binding ≤ 10μM |
| MERTK-1-E | Proto-oncogene Tyrosine-protein Kinase MER (cluster #1 Of 1), Eukaryotic | Eukaryotes | 66 | 0.31 | Binding ≤ 10μM |
| MKNK2-1-E | MAP Kinase Signal-integrating Kinase 2 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 5500 | 0.23 | Binding ≤ 10μM |
| MP2K1-1-E | Dual Specificity Mitogen-activated Protein Kinase Kinase 1 (cluster #1 Of 4), Eukaryotic | Eukaryotes | 77 | 0.31 | Binding ≤ 10μM |
| MP2K2-1-E | Dual Specificity Mitogen-activated Protein Kinase Kinase 2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 120 | 0.30 | Binding ≤ 10μM |
| MP2K4-1-E | Dual Specificity Mitogen-activated Protein Kinase Kinase 4 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1400 | 0.26 | Binding ≤ 10μM |
| MP2K6-1-E | Dual Specificity Mitogen-activated Protein Kinase Kinase 6 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 5500 | 0.23 | Binding ≤ 10μM |
| MST4-1-E | Serine/threonine-protein Kinase MST4 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 330 | 0.28 | Binding ≤ 10μM |
| MUSK-1-E | Muscle, Skeletal Receptor Tyrosine Protein Kinase (cluster #1 Of 1), Eukaryotic | Eukaryotes | 100 | 0.31 | Binding ≤ 10μM |
| MYLK-1-E | Myosin Light Chain Kinase, Smooth Muscle (cluster #1 Of 1), Eukaryotic | Eukaryotes | 360 | 0.28 | Binding ≤ 10μM |
| MYLK2-1-E | Myosin Light Chain Kinase 2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 190 | 0.29 | Binding ≤ 10μM |
| MYLK4-1-E | Myosin Light Chain Kinase Family Member 4 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 32 | 0.33 | Binding ≤ 10μM |
| NEK2-1-E | Serine/threonine-protein Kinase NEK2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1100 | 0.26 | Binding ≤ 10μM |
| NEK7-1-E | Serine/threonine-protein Kinase NEK7 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 3200 | 0.24 | Binding ≤ 10μM |
| NTRK1-1-E | Nerve Growth Factor Receptor Trk-A (cluster #1 Of 1), Eukaryotic | Eukaryotes | 480 | 0.28 | Binding ≤ 10μM |
| NTRK2-1-E | Neurotrophic Tyrosine Kinase Receptor Type 2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 990 | 0.26 | Binding ≤ 10μM |
| NTRK3-1-E | NT-3 Growth Factor Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 220 | 0.29 | Binding ≤ 10μM |
| NUAK1-1-E | NUAK Family SNF1-like Kinase 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 460 | 0.28 | Binding ≤ 10μM |
| NUAK2-1-E | NUAK Family SNF1-like Kinase 2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 400 | 0.28 | Binding ≤ 10μM |
| PAK3-1-E | Serine/threonine-protein Kinase PAK 3 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 190 | 0.29 | Binding ≤ 10μM |
| PDPK1-1-E | 3-phosphoinositide Dependent Protein Kinase-1 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 2600 | 0.24 | Binding ≤ 10μM |
| PGFRA-1-E | Platelet-derived Growth Factor Receptor Alpha (cluster #1 Of 2), Eukaryotic | Eukaryotes | 1 | 0.39 | Binding ≤ 10μM |
| PGFRB-1-E | Platelet-derived Growth Factor Receptor Beta (cluster #1 Of 1), Eukaryotic | Eukaryotes | 0 | 0.00 | Binding ≤ 10μM |
| PHKG1-1-E | Phosphorylase Kinase Gamma Subunit 1 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 83 | 0.31 | Binding ≤ 10μM |
| PHKG2-1-E | Phosphorylase Kinase Gamma Subunit 2 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 100 | 0.31 | Binding ≤ 10μM |
| PI42B-1-E | Phosphatidylinositol-5-phosphate 4-kinase Type-2 Beta (cluster #1 Of 1), Eukaryotic | Eukaryotes | 260 | 0.29 | Binding ≤ 10μM |
| PI51A-1-E | Phosphatidylinositol-4-phosphate 5-kinase Type-1 Alpha (cluster #1 Of 1), Eukaryotic | Eukaryotes | 130 | 0.30 | Binding ≤ 10μM |
| PIM3-1-E | Serine/threonine-protein Kinase PIM3 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 2400 | 0.25 | Binding ≤ 10μM |
| PKN1-1-E | Protein Kinase N1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1900 | 0.25 | Binding ≤ 10μM |
| PKN2-1-E | Protein Kinase N2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 3800 | 0.24 | Binding ≤ 10μM |
| PLK4-1-E | Serine/threonine-protein Kinase PLK4 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 180 | 0.30 | Binding ≤ 10μM |
| RET-1-E | Tyrosine-protein Kinase Receptor RET (cluster #1 Of 1), Eukaryotic | Eukaryotes | 37 | 0.33 | Binding ≤ 10μM |
| RIOK1-1-E | Serine/threonine-protein Kinase RIO1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 590 | 0.27 | Binding ≤ 10μM |
| RIOK3-1-E | Serine/threonine-protein Kinase RIO3 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 9700 | 0.22 | Binding ≤ 10μM |
| RIPK1-1-E | Receptor-interacting Serine/threonine-protein Kinase 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1200 | 0.26 | Binding ≤ 10μM |
| SIK1-1-E | Serine/threonine-protein Kinase SIK1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 2700 | 0.24 | Binding ≤ 10μM |
| SIK2-1-E | Serine/threonine-protein Kinase SIK2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 750 | 0.27 | Binding ≤ 10μM |
| SLK-1-E | Serine/threonine-protein Kinase 2 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 460 | 0.28 | Binding ≤ 10μM |
| SRC-1-E | Tyrosine-protein Kinase SRC (cluster #1 Of 3), Eukaryotic | Eukaryotes | 4900 | 0.23 | Binding ≤ 10μM |
| SRMS-1-E | Tyrosine-protein Kinase Srms (cluster #1 Of 1), Eukaryotic | Eukaryotes | 62 | 0.32 | Binding ≤ 10μM |
| SRPK1-1-E | Serine/threonine-protein Kinase SRPK1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 4000 | 0.24 | Binding ≤ 10μM |
| SRPK2-1-E | Serine/threonine-protein Kinase SRPK2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 200 | 0.29 | Binding ≤ 10μM |
| ST17A-1-E | Serine/threonine-protein Kinase 17A (cluster #1 Of 2), Eukaryotic | Eukaryotes | 24 | 0.33 | Binding ≤ 10μM |
| ST17B-1-E | Serine/threonine-protein Kinase 17B (cluster #1 Of 1), Eukaryotic | Eukaryotes | 320 | 0.28 | Binding ≤ 10μM |
| ST38L-1-E | Serine/threonine-protein Kinase 38-like (cluster #1 Of 2), Eukaryotic | Eukaryotes | 2000 | 0.25 | Binding ≤ 10μM |
| STK10-1-E | Serine/threonine-protein Kinase 10 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 230 | 0.29 | Binding ≤ 10μM |
| STK11-1-E | Serine/threonine-protein Kinase 11 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 360 | 0.28 | Binding ≤ 10μM |
| STK16-1-E | Serine/threonine-protein Kinase 16 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 730 | 0.27 | Binding ≤ 10μM |
| STK24-1-E | Serine/threonine-protein Kinase 24 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 100 | 0.31 | Binding ≤ 10μM |
| STK25-1-E | Serine/threonine-protein Kinase 25 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 360 | 0.28 | Binding ≤ 10μM |
| STK3-1-E | Serine/threonine-protein Kinase MST2 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 65 | 0.31 | Binding ≤ 10μM |
| STK33-1-E | Serine/threonine-protein Kinase 33 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 130 | 0.30 | Binding ≤ 10μM |
| STK4-1-E | Serine/threonine-protein Kinase MST1 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 130 | 0.30 | Binding ≤ 10μM |
| TLK1-1-E | Serine/threonine-protein Kinase Tousled-like 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 630 | 0.27 | Binding ≤ 10μM |
| TLK2-1-E | Serine/threonine-protein Kinase Tousled-like 2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 270 | 0.29 | Binding ≤ 10μM |
| TNIK-1-E | TRAF2- And NCK-interacting Kinase (cluster #1 Of 2), Eukaryotic | Eukaryotes | 90 | 0.31 | Binding ≤ 10μM |
| TNK1-1-E | Non-receptor Tyrosine-protein Kinase TNK1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1500 | 0.25 | Binding ≤ 10μM |
| TTK-1-E | Dual Specificity Protein Kinase TTK (cluster #1 Of 2), Eukaryotic | Eukaryotes | 180 | 0.30 | Binding ≤ 10μM |
| TYK2-1-E | Tyrosine-protein Kinase TYK2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 5100 | 0.23 | Binding ≤ 10μM |
| TYRO3-1-E | Tyrosine-protein Kinase Receptor TYRO3 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 2400 | 0.25 | Binding ≤ 10μM |
| UFO-1-E | Tyrosine-protein Kinase Receptor UFO (cluster #1 Of 1), Eukaryotic | Eukaryotes | 84 | 0.31 | Binding ≤ 10μM |
| VGFR1-1-E | Vascular Endothelial Growth Factor Receptor 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 5 | 0.36 | Binding ≤ 10μM |
| VGFR2-1-E | Vascular Endothelial Growth Factor Receptor 2 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 2 | 0.38 | Binding ≤ 10μM |
| VGFR3-1-E | Vascular Endothelial Growth Factor Receptor 3 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 50 | 0.32 | Binding ≤ 10μM |
| WEE1-1-E | Serine/threonine-protein Kinase WEE1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 3000 | 0.24 | Binding ≤ 10μM |
| YES-1-E | Tyrosine-protein Kinase YES (cluster #1 Of 1), Eukaryotic | Eukaryotes | 260 | 0.29 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| AAK1_HUMAN | Q2M2I8 | Adaptor-associated Kinase, Human | 66 | 0.31 | Binding ≤ 1μM |
| ALK_HUMAN | Q9UM73 | ALK Tyrosine Kinase Receptor, Human | 490 | 0.28 | Binding ≤ 1μM |
| AAPK1_HUMAN | Q13131 | AMP-activated Protein Kinase, Alpha-1 Subunit, Human | 100 | 0.31 | Binding ≤ 1μM |
| AAPK2_HUMAN | P54646 | AMP-activated Protein Kinase, Alpha-2 Subunit, Human | 290 | 0.29 | Binding ≤ 1μM |
| ANKK1_HUMAN | Q8NFD2 | Ankyrin Repeat And Protein Kinase Domain-containing Protein 1, Human | 160 | 0.30 | Binding ≤ 1μM |
| BMP2K_HUMAN | Q9NSY1 | BMP-2-inducible Protein Kinase, Human | 27 | 0.33 | Binding ≤ 1μM |
| BMPR2_HUMAN | Q13873 | Bone Morphogenetic Protein Receptor Type-2, Human | 200 | 0.29 | Binding ≤ 1μM |
| KCC1D_HUMAN | Q8IU85 | CaM Kinase I Delta, Human | 970 | 0.26 | Binding ≤ 1μM |
| KCC1G_HUMAN | Q96NX5 | CaM Kinase I Gamma, Human | 940 | 0.26 | Binding ≤ 1μM |
| KCC2A_HUMAN | Q9UQM7 | CaM Kinase II Alpha, Human | 350 | 0.28 | Binding ≤ 1μM |
| KCC2D_HUMAN | Q13557 | CaM Kinase II Delta, Human | 760 | 0.27 | Binding ≤ 1μM |
| KKCC1_HUMAN | Q8N5S9 | CaM-kinase Kinase Alpha, Human | 850 | 0.27 | Binding ≤ 1μM |
| KC1D_HUMAN | P48730 | Casein Kinase I Delta, Human | 260 | 0.29 | Binding ≤ 1μM |
| KC1E_HUMAN | P49674 | Casein Kinase I Epsilon, Human | 340 | 0.28 | Binding ≤ 1μM |
| KC1G1_HUMAN | Q9HCP0 | Casein Kinase I Gamma 1, Human | 1000 | 0.26 | Binding ≤ 1μM |
| KC1G2_HUMAN | P78368 | Casein Kinase I Gamma 2, Human | 790 | 0.27 | Binding ≤ 1μM |
| KC1G3_HUMAN | Q9Y6M4 | Casein Kinase I Isoform Gamma-3, Human | 570 | 0.27 | Binding ≤ 1μM |
| CSK21_HUMAN | P68400 | Casein Kinase II Alpha, Human | 97 | 0.31 | Binding ≤ 1μM |
| CSK22_HUMAN | P19784 | Casein Kinase II Alpha (prime), Human | 140 | 0.30 | Binding ≤ 1μM |
| CTRO_HUMAN | O14578 | Citron Rho-interacting Kinase, Human | 94 | 0.31 | Binding ≤ 1μM |
| CDK7_HUMAN | P50613 | Cyclin-dependent Kinase 7, Human | 930 | 0.26 | Binding ≤ 1μM |
| DAPK1_HUMAN | P53355 | Death-associated Protein Kinase 1, Human | 270 | 0.29 | Binding ≤ 1μM |
| DAPK2_HUMAN | Q9UIK4 | Death-associated Protein Kinase 2, Human | 400 | 0.28 | Binding ≤ 1μM |
| DAPK3_HUMAN | O43293 | Death-associated Protein Kinase 3, Human | 170 | 0.30 | Binding ≤ 1μM |
| MP2K1_HUMAN | Q02750 | Dual Specificity Mitogen-activated Protein Kinase Kinase 1, Human | 77 | 0.31 | Binding ≤ 1μM |
| MP2K2_HUMAN | P36507 | Dual Specificity Mitogen-activated Protein Kinase Kinase 2, Human | 120 | 0.30 | Binding ≤ 1μM |
| CLK2_HUMAN | P49760 | Dual Specificity Protein Kinase CLK2, Human | 150 | 0.30 | Binding ≤ 1μM |
| CLK4_HUMAN | Q9HAZ1 | Dual Specificity Protein Kinase CLK4, Human | 250 | 0.29 | Binding ≤ 1μM |
| TTK_HUMAN | P33981 | Dual Specificity Protein Kinase TTK, Human | 180 | 0.30 | Binding ≤ 1μM |
| CLK1_HUMAN | P49759 | Dual Specificty Protein Kinase CLK1, Human | 360 | 0.28 | Binding ≤ 1μM |
| E2AK4_HUMAN | Q9P2K8 | Eukaryotic Translation Initiation Factor 2-alpha Kinase 4, Human | 470 | 0.28 | Binding ≤ 1μM |
| FGFR2_HUMAN | P21802 | Fibroblast Growth Factor Receptor 2, Human | 790 | 0.27 | Binding ≤ 1μM |
| FGFR3_HUMAN | P22607 | Fibroblast Growth Factor Receptor 3, Human | 380 | 0.28 | Binding ≤ 1μM |
| IKKE_HUMAN | Q14164 | Inhibitor Of Nuclear Factor Kappa B Kinase Epsilon Subunit, Human | 480 | 0.28 | Binding ≤ 1μM |
| CSF1R_HUMAN | P07333 | Macrophage Colony Stimulating Factor Receptor, Human | 3.6 | 0.37 | Binding ≤ 1μM |
| MARK2_HUMAN | Q7KZI7 | MAP/microtubule Affinity-regulating Kinase 2, Human | 440 | 0.28 | Binding ≤ 1μM |
| MELK_HUMAN | Q14680 | Maternal Embryonic Leucine Zipper Kinase, Human | 340 | 0.28 | Binding ≤ 1μM |
| M4K1_HUMAN | Q92918 | Mitogen-activated Protein Kinase Kinase Kinase Kinase 1, Human | 15 | 0.34 | Binding ≤ 1μM |
| M4K3_HUMAN | Q8IVH8 | Mitogen-activated Protein Kinase Kinase Kinase Kinase 3, Human | 210 | 0.29 | Binding ≤ 1μM |
| M4K4_HUMAN | O95819 | Mitogen-activated Protein Kinase Kinase Kinase Kinase 4, Human | 260 | 0.29 | Binding ≤ 1μM |
| M4K5_HUMAN | Q9Y4K4 | Mitogen-activated Protein Kinase Kinase Kinase Kinase 5, Human | 300 | 0.29 | Binding ≤ 1μM |
| MUSK_HUMAN | O15146 | Muscle, Skeletal Receptor Tyrosine Protein Kinase, Human | 100 | 0.31 | Binding ≤ 1μM |
| MYLK2_HUMAN | Q9H1R3 | Myosin Light Chain Kinase 2, Human | 190 | 0.29 | Binding ≤ 1μM |
| MYLK4_HUMAN | Q86YV6 | Myosin Light Chain Kinase Family Member 4, Human | 32 | 0.33 | Binding ≤ 1μM |
| MYLK_CHICK | P11799 | Myosin Light Chain Kinase, Smooth Muscle, Chick | 42 | 0.32 | Binding ≤ 1μM |
| MYLK_HUMAN | Q15746 | Myosin Light Chain Kinase, Smooth Muscle, Human | 360 | 0.28 | Binding ≤ 1μM |
| NTRK1_HUMAN | P04629 | Nerve Growth Factor Receptor Trk-A, Human | 480 | 0.28 | Binding ≤ 1μM |
| NTRK2_HUMAN | Q16620 | Neurotrophic Tyrosine Kinase Receptor Type 2, Human | 990 | 0.26 | Binding ≤ 1μM |
| NTRK3_HUMAN | Q16288 | NT-3 Growth Factor Receptor, Human | 220 | 0.29 | Binding ≤ 1μM |
| NUAK1_HUMAN | O60285 | NUAK Family SNF1-like Kinase 1, Human | 460 | 0.28 | Binding ≤ 1μM |
| NUAK2_HUMAN | Q9H093 | NUAK Family SNF1-like Kinase 2, Human | 400 | 0.28 | Binding ≤ 1μM |
| PI51A_HUMAN | Q99755 | Phosphatidylinositol-4-phosphate 5-kinase Type-1 Alpha, Human | 130 | 0.30 | Binding ≤ 1μM |
| PI42B_HUMAN | P78356 | Phosphatidylinositol-5-phosphate 4-kinase Type-2 Beta, Human | 260 | 0.29 | Binding ≤ 1μM |
| PHKG1_HUMAN | Q16816 | Phosphorylase Kinase Gamma Subunit 1, Human | 83 | 0.31 | Binding ≤ 1μM |
| PHKG2_HUMAN | P15735 | Phosphorylase Kinase Gamma Subunit 2, Human | 100 | 0.31 | Binding ≤ 1μM |
| PGFRA_HUMAN | P16234 | Platelet-derived Growth Factor Receptor Alpha, Human | 1.1 | 0.39 | Binding ≤ 1μM |
| PGFRB_HUMAN | P09619 | Platelet-derived Growth Factor Receptor Beta, Human | 0.29 | 0.42 | Binding ≤ 1μM |
| FAK2_HUMAN | Q14289 | Protein Tyrosine Kinase 2 Beta, Human | 600 | 0.27 | Binding ≤ 1μM |
| MERTK_HUMAN | Q12866 | Proto-oncogene Tyrosine-protein Kinase MER, Human | 66 | 0.31 | Binding ≤ 1μM |
| KS6A1_HUMAN | Q15418 | Ribosomal Protein S6 Kinase Alpha 1, Human | 180 | 0.30 | Binding ≤ 1μM |
| KS6A2_HUMAN | Q15349 | Ribosomal Protein S6 Kinase Alpha 2, Human | 260 | 0.29 | Binding ≤ 1μM |
| KS6A4_HUMAN | O75676 | Ribosomal Protein S6 Kinase Alpha 4, Human | 200 | 0.29 | Binding ≤ 1μM |
| KS6A5_HUMAN | O75582 | Ribosomal Protein S6 Kinase Alpha 5, Human | 150 | 0.30 | Binding ≤ 1μM |
| STK10_HUMAN | O94804 | Serine/threonine-protein Kinase 10, Human | 230 | 0.29 | Binding ≤ 1μM |
| STK11_HUMAN | Q15831 | Serine/threonine-protein Kinase 11, Human | 360 | 0.28 | Binding ≤ 1μM |
| STK16_HUMAN | O75716 | Serine/threonine-protein Kinase 16, Human | 730 | 0.27 | Binding ≤ 1μM |
| ST17A_HUMAN | Q9UEE5 | Serine/threonine-protein Kinase 17A, Human | 24 | 0.33 | Binding ≤ 1μM |
| ST17B_HUMAN | O94768 | Serine/threonine-protein Kinase 17B, Human | 320 | 0.28 | Binding ≤ 1μM |
| SLK_HUMAN | Q9H2G2 | Serine/threonine-protein Kinase 2, Human | 460 | 0.28 | Binding ≤ 1μM |
| STK24_HUMAN | Q9Y6E0 | Serine/threonine-protein Kinase 24, Human | 100 | 0.31 | Binding ≤ 1μM |
| STK25_HUMAN | O00506 | Serine/threonine-protein Kinase 25, Human | 360 | 0.28 | Binding ≤ 1μM |
| STK33_HUMAN | Q9BYT3 | Serine/threonine-protein Kinase 33, Human | 130 | 0.30 | Binding ≤ 1μM |
| AURKB_HUMAN | Q96GD4 | Serine/threonine-protein Kinase Aurora-B, Human | 340 | 0.28 | Binding ≤ 1μM |
| AURKC_HUMAN | Q9UQB9 | Serine/threonine-protein Kinase Aurora-C, Human | 810 | 0.27 | Binding ≤ 1μM |
| DCLK1_HUMAN | O15075 | Serine/threonine-protein Kinase DCLK1, Human | 550 | 0.27 | Binding ≤ 1μM |
| DCLK3_HUMAN | Q9C098 | Serine/threonine-protein Kinase DCLK3, Human | 240 | 0.29 | Binding ≤ 1μM |
| GAK_HUMAN | O14976 | Serine/threonine-protein Kinase GAK, Human | 44 | 0.32 | Binding ≤ 1μM |
| LATS1_HUMAN | O95835 | Serine/threonine-protein Kinase LATS1, Human | 850 | 0.27 | Binding ≤ 1μM |
| LATS2_HUMAN | Q9NRM7 | Serine/threonine-protein Kinase LATS2, Human | 430 | 0.28 | Binding ≤ 1μM |
| STK4_HUMAN | Q13043 | Serine/threonine-protein Kinase MST1, Human | 130 | 0.30 | Binding ≤ 1μM |
| STK3_HUMAN | Q13188 | Serine/threonine-protein Kinase MST2, Human | 65 | 0.31 | Binding ≤ 1μM |
| MST4_HUMAN | Q9P289 | Serine/threonine-protein Kinase MST4, Human | 330 | 0.28 | Binding ≤ 1μM |
| PAK3_HUMAN | O75914 | Serine/threonine-protein Kinase PAK 3, Human | 190 | 0.29 | Binding ≤ 1μM |
| CDK16_HUMAN | Q00536 | Serine/threonine-protein Kinase PCTAIRE-1, Human | 940 | 0.26 | Binding ≤ 1μM |
| PLK4_HUMAN | O00444 | Serine/threonine-protein Kinase PLK4, Human | 180 | 0.30 | Binding ≤ 1μM |
| RIOK1_HUMAN | Q9BRS2 | Serine/threonine-protein Kinase RIO1, Human | 590 | 0.27 | Binding ≤ 1μM |
| SIK2_HUMAN | Q9H0K1 | Serine/threonine-protein Kinase SIK2, Human | 750 | 0.27 | Binding ≤ 1μM |
| SRPK2_HUMAN | P78362 | Serine/threonine-protein Kinase SRPK2, Human | 200 | 0.29 | Binding ≤ 1μM |
| TLK1_HUMAN | Q9UKI8 | Serine/threonine-protein Kinase Tousled-like 1, Human | 630 | 0.27 | Binding ≤ 1μM |
| TLK2_HUMAN | Q86UE8 | Serine/threonine-protein Kinase Tousled-like 2, Human | 270 | 0.29 | Binding ≤ 1μM |
| KIT_HUMAN | P10721 | Stem Cell Growth Factor Receptor, Human | 0.68 | 0.40 | Binding ≤ 1μM |
| TNIK_HUMAN | Q9UKE5 | TRAF2- And NCK-interacting Kinase, Human | 90 | 0.31 | Binding ≤ 1μM |
| ABL1_HUMAN | P00519 | Tyrosine-protein Kinase ABL, Human | 260 | 0.29 | Binding ≤ 1μM |
| BLK_HUMAN | P51451 | Tyrosine-protein Kinase BLK, Human | 750 | 0.27 | Binding ≤ 1μM |
| FER_HUMAN | P16591 | Tyrosine-protein Kinase FER, Human | 34 | 0.33 | Binding ≤ 1μM |
| FGR_HUMAN | P09769 | Tyrosine-protein Kinase FGR, Human | 390 | 0.28 | Binding ≤ 1μM |
| ITK_HUMAN | Q08881 | Tyrosine-protein Kinase ITK/TSK, Human | 190 | 0.29 | Binding ≤ 1μM |
| JAK1_HUMAN | P23458 | Tyrosine-protein Kinase JAK1, Human | 97 | 0.31 | Binding ≤ 1μM |
| JAK3_HUMAN | P52333 | Tyrosine-protein Kinase JAK3, Human | 580 | 0.27 | Binding ≤ 1μM |
| LYN_HUMAN | P07948 | Tyrosine-protein Kinase Lyn, Human | 810 | 0.27 | Binding ≤ 1μM |
| FLT3_HUMAN | P36888 | Tyrosine-protein Kinase Receptor FLT3, Human | 0.54 | 0.41 | Binding ≤ 1μM |
| RET_HUMAN | P07949 | Tyrosine-protein Kinase Receptor RET, Human | 24 | 0.33 | Binding ≤ 1μM |
| UFO_HUMAN | P30530 | Tyrosine-protein Kinase Receptor UFO, Human | 84 | 0.31 | Binding ≤ 1μM |
| SRMS_HUMAN | Q9H3Y6 | Tyrosine-protein Kinase Srms, Human | 62 | 0.32 | Binding ≤ 1μM |
| YES_HUMAN | P07947 | Tyrosine-protein Kinase YES, Human | 260 | 0.29 | Binding ≤ 1μM |
| VGFR1_HUMAN | P17948 | Vascular Endothelial Growth Factor Receptor 1, Human | 4.7 | 0.36 | Binding ≤ 1μM |
| VGFR2_HUMAN | P35968 | Vascular Endothelial Growth Factor Receptor 2, Human | 2.3 | 0.38 | Binding ≤ 1μM |
| VGFR3_HUMAN | P35916 | Vascular Endothelial Growth Factor Receptor 3, Human | 50 | 0.32 | Binding ≤ 1μM |
| PDPK1_HUMAN | O15530 | 3-phosphoinositide Dependent Protein Kinase-1, Human | 2600 | 0.24 | Binding ≤ 10μM |
| AAK1_HUMAN | Q2M2I8 | Adaptor-associated Kinase, Human | 66 | 0.31 | Binding ≤ 10μM |
| ALK_HUMAN | Q9UM73 | ALK Tyrosine Kinase Receptor, Human | 490 | 0.28 | Binding ≤ 10μM |
| AAPK1_HUMAN | Q13131 | AMP-activated Protein Kinase, Alpha-1 Subunit, Human | 100 | 0.31 | Binding ≤ 10μM |
| AAPK2_HUMAN | P54646 | AMP-activated Protein Kinase, Alpha-2 Subunit, Human | 290 | 0.29 | Binding ≤ 10μM |
| ANKK1_HUMAN | Q8NFD2 | Ankyrin Repeat And Protein Kinase Domain-containing Protein 1, Human | 160 | 0.30 | Binding ≤ 10μM |
| BMP2K_HUMAN | Q9NSY1 | BMP-2-inducible Protein Kinase, Human | 27 | 0.33 | Binding ≤ 10μM |
| BMPR2_HUMAN | Q13873 | Bone Morphogenetic Protein Receptor Type-2, Human | 200 | 0.29 | Binding ≤ 10μM |
| BRSK1_HUMAN | Q8TDC3 | BR Serine/threonine-protein Kinase 1, Human | 5000 | 0.23 | Binding ≤ 10μM |
| BRSK2_HUMAN | Q8IWQ3 | BR Serine/threonine-protein Kinase 2, Human | 4100 | 0.24 | Binding ≤ 10μM |
| KCC1A_HUMAN | Q14012 | CaM Kinase I Alpha, Human | 3300 | 0.24 | Binding ≤ 10μM |
| KCC1D_HUMAN | Q8IU85 | CaM Kinase I Delta, Human | 970 | 0.26 | Binding ≤ 10μM |
| KCC1G_HUMAN | Q96NX5 | CaM Kinase I Gamma, Human | 940 | 0.26 | Binding ≤ 10μM |
| KCC2A_HUMAN | Q9UQM7 | CaM Kinase II Alpha, Human | 350 | 0.28 | Binding ≤ 10μM |
| KCC2B_HUMAN | Q13554 | CaM Kinase II Beta, Human | 2300 | 0.25 | Binding ≤ 10μM |
| KCC2D_HUMAN | Q13557 | CaM Kinase II Delta, Human | 760 | 0.27 | Binding ≤ 10μM |
| KCC2G_HUMAN | Q13555 | CaM Kinase II Gamma, Human | 1100 | 0.26 | Binding ≤ 10μM |
| KCC4_HUMAN | Q16566 | CaM Kinase IV, Human | 2700 | 0.24 | Binding ≤ 10μM |
| KKCC1_HUMAN | Q8N5S9 | CaM-kinase Kinase Alpha, Human | 850 | 0.27 | Binding ≤ 10μM |
| KKCC2_HUMAN | Q96RR4 | CaM-kinase Kinase Beta, Human | 2500 | 0.25 | Binding ≤ 10μM |
| KC1D_HUMAN | P48730 | Casein Kinase I Delta, Human | 260 | 0.29 | Binding ≤ 10μM |
| KC1E_HUMAN | P49674 | Casein Kinase I Epsilon, Human | 340 | 0.28 | Binding ≤ 10μM |
| KC1G1_HUMAN | Q9HCP0 | Casein Kinase I Gamma 1, Human | 1000 | 0.26 | Binding ≤ 10μM |
| KC1G2_HUMAN | P78368 | Casein Kinase I Gamma 2, Human | 790 | 0.27 | Binding ≤ 10μM |
| KC1AL_HUMAN | Q8N752 | Casein Kinase I Isoform Alpha-like, Human | 1500 | 0.25 | Binding ≤ 10μM |
| KC1G3_HUMAN | Q9Y6M4 | Casein Kinase I Isoform Gamma-3, Human | 570 | 0.27 | Binding ≤ 10μM |
| CSK21_HUMAN | P68400 | Casein Kinase II Alpha, Human | 97 | 0.31 | Binding ≤ 10μM |
| CSK22_HUMAN | P19784 | Casein Kinase II Alpha (prime), Human | 140 | 0.30 | Binding ≤ 10μM |
| CTRO_HUMAN | O14578 | Citron Rho-interacting Kinase, Human | 94 | 0.31 | Binding ≤ 10μM |
| CDK7_HUMAN | P50613 | Cyclin-dependent Kinase 7, Human | 930 | 0.26 | Binding ≤ 10μM |
| DAPK1_HUMAN | P53355 | Death-associated Protein Kinase 1, Human | 270 | 0.29 | Binding ≤ 10μM |
| DAPK2_HUMAN | Q9UIK4 | Death-associated Protein Kinase 2, Human | 400 | 0.28 | Binding ≤ 10μM |
| DAPK3_HUMAN | O43293 | Death-associated Protein Kinase 3, Human | 170 | 0.30 | Binding ≤ 10μM |
| MP2K1_HUMAN | Q02750 | Dual Specificity Mitogen-activated Protein Kinase Kinase 1, Human | 77 | 0.31 | Binding ≤ 10μM |
| MP2K2_HUMAN | P36507 | Dual Specificity Mitogen-activated Protein Kinase Kinase 2, Human | 120 | 0.30 | Binding ≤ 10μM |
| MP2K4_HUMAN | P45985 | Dual Specificity Mitogen-activated Protein Kinase Kinase 4, Human | 1400 | 0.26 | Binding ≤ 10μM |
| MP2K6_HUMAN | P52564 | Dual Specificity Mitogen-activated Protein Kinase Kinase 6, Human | 5500 | 0.23 | Binding ≤ 10μM |
| CLK2_HUMAN | P49760 | Dual Specificity Protein Kinase CLK2, Human | 150 | 0.30 | Binding ≤ 10μM |
| CLK4_HUMAN | Q9HAZ1 | Dual Specificity Protein Kinase CLK4, Human | 250 | 0.29 | Binding ≤ 10μM |
| TTK_HUMAN | P33981 | Dual Specificity Protein Kinase TTK, Human | 180 | 0.30 | Binding ≤ 10μM |
| DYR1B_HUMAN | Q9Y463 | Dual Specificity Tyrosine-phosphorylation-regulated Kinase 1B, Human | 2600 | 0.24 | Binding ≤ 10μM |
| CLK1_HUMAN | P49759 | Dual Specificty Protein Kinase CLK1, Human | 360 | 0.28 | Binding ≤ 10μM |
| EPHA6_HUMAN | Q9UF33 | Ephrin Type-A Receptor 6, Human | 2000 | 0.25 | Binding ≤ 10μM |
| EGFR_HUMAN | P00533 | Epidermal Growth Factor Receptor ErbB1, Human | 9000 | 0.22 | Binding ≤ 10μM |
| E2AK4_HUMAN | Q9P2K8 | Eukaryotic Translation Initiation Factor 2-alpha Kinase 4, Human | 470 | 0.28 | Binding ≤ 10μM |
| FGFR1_HUMAN | P11362 | Fibroblast Growth Factor Receptor 1, Human | 1900 | 0.25 | Binding ≤ 10μM |
| FGFR2_HUMAN | P21802 | Fibroblast Growth Factor Receptor 2, Human | 790 | 0.27 | Binding ≤ 10μM |
| FGFR3_HUMAN | P22607 | Fibroblast Growth Factor Receptor 3, Human | 380 | 0.28 | Binding ≤ 10μM |
| FAK1_HUMAN | Q05397 | Focal Adhesion Kinase 1, Human | 1200 | 0.26 | Binding ≤ 10μM |
| IKKE_HUMAN | Q14164 | Inhibitor Of Nuclear Factor Kappa B Kinase Epsilon Subunit, Human | 480 | 0.28 | Binding ≤ 10μM |
| INSR_HUMAN | P06213 | Insulin Receptor, Human | 1200 | 0.26 | Binding ≤ 10μM |
| INSRR_HUMAN | P14616 | Insulin Receptor-related Protein, Human | 2000 | 0.25 | Binding ≤ 10μM |
| E2AK2_HUMAN | P19525 | Interferon-induced, Double-stranded RNA-activated Protein Kinase, Human | 1300 | 0.26 | Binding ≤ 10μM |
| IRAK3_HUMAN | Q9Y616 | Interleukin-1 Receptor-associated Kinase 3, Human | 1900 | 0.25 | Binding ≤ 10μM |
| LTK_HUMAN | P29376 | Leukocyte Tyrosine Kinase Receptor, Human | 4200 | 0.24 | Binding ≤ 10μM |
| CSF1R_HUMAN | P07333 | Macrophage Colony Stimulating Factor Receptor, Human | 3.6 | 0.37 | Binding ≤ 10μM |
| MKNK2_HUMAN | Q9HBH9 | MAP Kinase Signal-integrating Kinase 2, Human | 5500 | 0.23 | Binding ≤ 10μM |
| MARK2_HUMAN | Q7KZI7 | MAP/microtubule Affinity-regulating Kinase 2, Human | 440 | 0.28 | Binding ≤ 10μM |
| MARK4_HUMAN | Q96L34 | MAP/microtubule Affinity-regulating Kinase 4, Human | 2000 | 0.25 | Binding ≤ 10μM |
| MELK_HUMAN | Q14680 | Maternal Embryonic Leucine Zipper Kinase, Human | 340 | 0.28 | Binding ≤ 10μM |
| M3K11_HUMAN | Q16584 | Mitogen-activated Protein Kinase Kinase Kinase 11, Human | 1700 | 0.25 | Binding ≤ 10μM |
| M3K9_HUMAN | P80192 | Mitogen-activated Protein Kinase Kinase Kinase 9, Human | 2600 | 0.24 | Binding ≤ 10μM |
| M4K1_HUMAN | Q92918 | Mitogen-activated Protein Kinase Kinase Kinase Kinase 1, Human | 15 | 0.34 | Binding ≤ 10μM |
| M4K3_HUMAN | Q8IVH8 | Mitogen-activated Protein Kinase Kinase Kinase Kinase 3, Human | 210 | 0.29 | Binding ≤ 10μM |
| M4K4_HUMAN | O95819 | Mitogen-activated Protein Kinase Kinase Kinase Kinase 4, Human | 260 | 0.29 | Binding ≤ 10μM |
| M4K5_HUMAN | Q9Y4K4 | Mitogen-activated Protein Kinase Kinase Kinase Kinase 5, Human | 300 | 0.29 | Binding ≤ 10μM |
| MUSK_HUMAN | O15146 | Muscle, Skeletal Receptor Tyrosine Protein Kinase, Human | 100 | 0.31 | Binding ≤ 10μM |
| MYLK2_HUMAN | Q9H1R3 | Myosin Light Chain Kinase 2, Human | 190 | 0.29 | Binding ≤ 10μM |
| MYLK4_HUMAN | Q86YV6 | Myosin Light Chain Kinase Family Member 4, Human | 32 | 0.33 | Binding ≤ 10μM |
| MYLK_HUMAN | Q15746 | Myosin Light Chain Kinase, Smooth Muscle, Human | 360 | 0.28 | Binding ≤ 10μM |
| MYLK_CHICK | P11799 | Myosin Light Chain Kinase, Smooth Muscle, Chick | 42 | 0.32 | Binding ≤ 10μM |
| NTRK1_HUMAN | P04629 | Nerve Growth Factor Receptor Trk-A, Human | 480 | 0.28 | Binding ≤ 10μM |
| NTRK2_HUMAN | Q16620 | Neurotrophic Tyrosine Kinase Receptor Type 2, Human | 990 | 0.26 | Binding ≤ 10μM |
| TNK1_HUMAN | Q13470 | Non-receptor Tyrosine-protein Kinase TNK1, Human | 1500 | 0.25 | Binding ≤ 10μM |
| NTRK3_HUMAN | Q16288 | NT-3 Growth Factor Receptor, Human | 220 | 0.29 | Binding ≤ 10μM |
| NUAK1_HUMAN | O60285 | NUAK Family SNF1-like Kinase 1, Human | 460 | 0.28 | Binding ≤ 10μM |
| NUAK2_HUMAN | Q9H093 | NUAK Family SNF1-like Kinase 2, Human | 400 | 0.28 | Binding ≤ 10μM |
| PI51A_HUMAN | Q99755 | Phosphatidylinositol-4-phosphate 5-kinase Type-1 Alpha, Human | 130 | 0.30 | Binding ≤ 10μM |
| PI42B_HUMAN | P78356 | Phosphatidylinositol-5-phosphate 4-kinase Type-2 Beta, Human | 260 | 0.29 | Binding ≤ 10μM |
| PHKG1_HUMAN | Q16816 | Phosphorylase Kinase Gamma Subunit 1, Human | 83 | 0.31 | Binding ≤ 10μM |
| PHKG2_HUMAN | P15735 | Phosphorylase Kinase Gamma Subunit 2, Human | 100 | 0.31 | Binding ≤ 10μM |
| PGFRA_HUMAN | P16234 | Platelet-derived Growth Factor Receptor Alpha, Human | 1.1 | 0.39 | Binding ≤ 10μM |
| PGFRB_HUMAN | P09619 | Platelet-derived Growth Factor Receptor Beta, Human | 0.29 | 0.42 | Binding ≤ 10μM |
| KPCD1_HUMAN | Q15139 | Protein Kinase C Mu, Human | 2400 | 0.25 | Binding ≤ 10μM |
| KPCD3_HUMAN | O94806 | Protein Kinase C Nu, Human | 2700 | 0.24 | Binding ≤ 10μM |
| KPCT_HUMAN | Q04759 | Protein Kinase C Theta, Human | 7200 | 0.22 | Binding ≤ 10μM |
| PKN1_HUMAN | Q16512 | Protein Kinase N1, Human | 1900 | 0.25 | Binding ≤ 10μM |
| PKN2_HUMAN | Q16513 | Protein Kinase N2, Human | 3800 | 0.24 | Binding ≤ 10μM |
| FAK2_HUMAN | Q14289 | Protein Tyrosine Kinase 2 Beta, Human | 600 | 0.27 | Binding ≤ 10μM |
| MERTK_HUMAN | Q12866 | Proto-oncogene Tyrosine-protein Kinase MER, Human | 66 | 0.31 | Binding ≤ 10μM |
| RIPK1_HUMAN | Q13546 | Receptor-interacting Serine/threonine-protein Kinase 1, Human | 1200 | 0.26 | Binding ≤ 10μM |
| KS6A1_HUMAN | Q15418 | Ribosomal Protein S6 Kinase Alpha 1, Human | 180 | 0.30 | Binding ≤ 10μM |
| KS6A2_HUMAN | Q15349 | Ribosomal Protein S6 Kinase Alpha 2, Human | 260 | 0.29 | Binding ≤ 10μM |
| KS6A3_HUMAN | P51812 | Ribosomal Protein S6 Kinase Alpha 3, Human | 2100 | 0.25 | Binding ≤ 10μM |
| KS6A4_HUMAN | O75676 | Ribosomal Protein S6 Kinase Alpha 4, Human | 200 | 0.29 | Binding ≤ 10μM |
| KS6A5_HUMAN | O75582 | Ribosomal Protein S6 Kinase Alpha 5, Human | 150 | 0.30 | Binding ≤ 10μM |
| KS6A6_HUMAN | Q9UK32 | Ribosomal Protein S6 Kinase Alpha 6, Human | 3100 | 0.24 | Binding ≤ 10μM |
| STK10_HUMAN | O94804 | Serine/threonine-protein Kinase 10, Human | 230 | 0.29 | Binding ≤ 10μM |
| STK11_HUMAN | Q15831 | Serine/threonine-protein Kinase 11, Human | 360 | 0.28 | Binding ≤ 10μM |
| STK16_HUMAN | O75716 | Serine/threonine-protein Kinase 16, Human | 730 | 0.27 | Binding ≤ 10μM |
| ST17A_HUMAN | Q9UEE5 | Serine/threonine-protein Kinase 17A, Human | 24 | 0.33 | Binding ≤ 10μM |
| ST17B_HUMAN | O94768 | Serine/threonine-protein Kinase 17B, Human | 320 | 0.28 | Binding ≤ 10μM |
| SLK_HUMAN | Q9H2G2 | Serine/threonine-protein Kinase 2, Human | 460 | 0.28 | Binding ≤ 10μM |
| STK24_HUMAN | Q9Y6E0 | Serine/threonine-protein Kinase 24, Human | 100 | 0.31 | Binding ≤ 10μM |
| STK25_HUMAN | O00506 | Serine/threonine-protein Kinase 25, Human | 360 | 0.28 | Binding ≤ 10μM |
| STK33_HUMAN | Q9BYT3 | Serine/threonine-protein Kinase 33, Human | 130 | 0.30 | Binding ≤ 10μM |
| ST38L_HUMAN | Q9Y2H1 | Serine/threonine-protein Kinase 38-like, Human | 2000 | 0.25 | Binding ≤ 10μM |
| AURKB_HUMAN | Q96GD4 | Serine/threonine-protein Kinase Aurora-B, Human | 340 | 0.28 | Binding ≤ 10μM |
| AURKC_HUMAN | Q9UQB9 | Serine/threonine-protein Kinase Aurora-C, Human | 810 | 0.27 | Binding ≤ 10μM |
| MARK3_HUMAN | P27448 | Serine/threonine-protein Kinase C-TAK1, Human | 1100 | 0.26 | Binding ≤ 10μM |
| CHK1_HUMAN | O14757 | Serine/threonine-protein Kinase Chk1, Human | 1200 | 0.26 | Binding ≤ 10μM |
| KPCD2_HUMAN | Q9BZL6 | Serine/threonine-protein Kinase D2, Human | 3700 | 0.24 | Binding ≤ 10μM |
| DCLK1_HUMAN | O15075 | Serine/threonine-protein Kinase DCLK1, Human | 550 | 0.27 | Binding ≤ 10μM |
| DCLK3_HUMAN | Q9C098 | Serine/threonine-protein Kinase DCLK3, Human | 240 | 0.29 | Binding ≤ 10μM |
| GAK_HUMAN | O14976 | Serine/threonine-protein Kinase GAK, Human | 44 | 0.32 | Binding ≤ 10μM |
| LATS1_HUMAN | O95835 | Serine/threonine-protein Kinase LATS1, Human | 850 | 0.27 | Binding ≤ 10μM |
| LATS2_HUMAN | Q9NRM7 | Serine/threonine-protein Kinase LATS2, Human | 430 | 0.28 | Binding ≤ 10μM |
| MARK1_HUMAN | Q9P0L2 | Serine/threonine-protein Kinase MARK1, Human | 1500 | 0.25 | Binding ≤ 10μM |
| STK4_HUMAN | Q13043 | Serine/threonine-protein Kinase MST1, Human | 130 | 0.30 | Binding ≤ 10μM |
| STK3_HUMAN | Q13188 | Serine/threonine-protein Kinase MST2, Human | 65 | 0.31 | Binding ≤ 10μM |
| MST4_HUMAN | Q9P289 | Serine/threonine-protein Kinase MST4, Human | 330 | 0.28 | Binding ≤ 10μM |
| NEK2_HUMAN | P51955 | Serine/threonine-protein Kinase NEK2, Human | 1100 | 0.26 | Binding ≤ 10μM |
| NEK7_HUMAN | Q8TDX7 | Serine/threonine-protein Kinase NEK7, Human | 3200 | 0.24 | Binding ≤ 10μM |
| PAK3_HUMAN | O75914 | Serine/threonine-protein Kinase PAK 3, Human | 190 | 0.29 | Binding ≤ 10μM |
| CDK16_HUMAN | Q00536 | Serine/threonine-protein Kinase PCTAIRE-1, Human | 940 | 0.26 | Binding ≤ 10μM |
| PIM3_HUMAN | Q86V86 | Serine/threonine-protein Kinase PIM3, Human | 2400 | 0.25 | Binding ≤ 10μM |
| PLK4_HUMAN | O00444 | Serine/threonine-protein Kinase PLK4, Human | 180 | 0.30 | Binding ≤ 10μM |
| RIOK1_HUMAN | Q9BRS2 | Serine/threonine-protein Kinase RIO1, Human | 590 | 0.27 | Binding ≤ 10μM |
| RIOK3_HUMAN | O14730 | Serine/threonine-protein Kinase RIO3, Human | 9700 | 0.22 | Binding ≤ 10μM |
| SIK1_HUMAN | P57059 | Serine/threonine-protein Kinase SIK1, Human | 2700 | 0.24 | Binding ≤ 10μM |
| SIK2_HUMAN | Q9H0K1 | Serine/threonine-protein Kinase SIK2, Human | 750 | 0.27 | Binding ≤ 10μM |
| SRPK1_HUMAN | Q96SB4 | Serine/threonine-protein Kinase SRPK1, Human | 4000 | 0.24 | Binding ≤ 10μM |
| SRPK2_HUMAN | P78362 | Serine/threonine-protein Kinase SRPK2, Human | 200 | 0.29 | Binding ≤ 10μM |
| TLK1_HUMAN | Q9UKI8 | Serine/threonine-protein Kinase Tousled-like 1, Human | 630 | 0.27 | Binding ≤ 10μM |
| TLK2_HUMAN | Q86UE8 | Serine/threonine-protein Kinase Tousled-like 2, Human | 270 | 0.29 | Binding ≤ 10μM |
| WEE1_HUMAN | P30291 | Serine/threonine-protein Kinase WEE1, Human | 3000 | 0.24 | Binding ≤ 10μM |
| KIT_HUMAN | P10721 | Stem Cell Growth Factor Receptor, Human | 0.68 | 0.40 | Binding ≤ 10μM |
| TNIK_HUMAN | Q9UKE5 | TRAF2- And NCK-interacting Kinase, Human | 90 | 0.31 | Binding ≤ 10μM |
| ACK1_HUMAN | Q07912 | Tyrosine Kinase Non-receptor Protein 2, Human | 4900 | 0.23 | Binding ≤ 10μM |
| ABL1_HUMAN | P00519 | Tyrosine-protein Kinase ABL, Human | 1200 | 0.26 | Binding ≤ 10μM |
| BLK_HUMAN | P51451 | Tyrosine-protein Kinase BLK, Human | 750 | 0.27 | Binding ≤ 10μM |
| FER_HUMAN | P16591 | Tyrosine-protein Kinase FER, Human | 34 | 0.33 | Binding ≤ 10μM |
| FGR_HUMAN | P09769 | Tyrosine-protein Kinase FGR, Human | 390 | 0.28 | Binding ≤ 10μM |
| FYN_HUMAN | P06241 | Tyrosine-protein Kinase FYN, Human | 2600 | 0.24 | Binding ≤ 10μM |
| HCK_HUMAN | P08631 | Tyrosine-protein Kinase HCK, Human | 2200 | 0.25 | Binding ≤ 10μM |
| ITK_HUMAN | Q08881 | Tyrosine-protein Kinase ITK/TSK, Human | 190 | 0.29 | Binding ≤ 10μM |
| JAK1_HUMAN | P23458 | Tyrosine-protein Kinase JAK1, Human | 97 | 0.31 | Binding ≤ 10μM |
| JAK2_HUMAN | O60674 | Tyrosine-protein Kinase JAK2, Human | 1600 | 0.25 | Binding ≤ 10μM |
| JAK3_HUMAN | P52333 | Tyrosine-protein Kinase JAK3, Human | 580 | 0.27 | Binding ≤ 10μM |
| LCK_HUMAN | P06239 | Tyrosine-protein Kinase LCK, Human | 2300 | 0.25 | Binding ≤ 10μM |
| LYN_HUMAN | P07948 | Tyrosine-protein Kinase Lyn, Human | 810 | 0.27 | Binding ≤ 10μM |
| FLT3_HUMAN | P36888 | Tyrosine-protein Kinase Receptor FLT3, Human | 0.54 | 0.41 | Binding ≤ 10μM |
| RET_HUMAN | P07949 | Tyrosine-protein Kinase Receptor RET, Human | 24 | 0.33 | Binding ≤ 10μM |
| TYRO3_HUMAN | Q06418 | Tyrosine-protein Kinase Receptor TYRO3, Human | 2400 | 0.25 | Binding ≤ 10μM |
| UFO_HUMAN | P30530 | Tyrosine-protein Kinase Receptor UFO, Human | 84 | 0.31 | Binding ≤ 10μM |
| SRC_HUMAN | P12931 | Tyrosine-protein Kinase SRC, Human | 4900 | 0.23 | Binding ≤ 10μM |
| SRMS_HUMAN | Q9H3Y6 | Tyrosine-protein Kinase Srms, Human | 62 | 0.32 | Binding ≤ 10μM |
| TYK2_HUMAN | P29597 | Tyrosine-protein Kinase TYK2, Human | 5100 | 0.23 | Binding ≤ 10μM |
| YES_HUMAN | P07947 | Tyrosine-protein Kinase YES, Human | 260 | 0.29 | Binding ≤ 10μM |
| VGFR1_HUMAN | P17948 | Vascular Endothelial Growth Factor Receptor 1, Human | 4.7 | 0.36 | Binding ≤ 10μM |
| VGFR2_HUMAN | P35968 | Vascular Endothelial Growth Factor Receptor 2, Human | 2.3 | 0.38 | Binding ≤ 10μM |
| VGFR3_HUMAN | P35916 | Vascular Endothelial Growth Factor Receptor 3, Human | 50 | 0.32 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Activated point mutants of FGFR2 | |
| activated TAK1 mediates p38 MAPK activation | |
| Activation of ATR in response to replication stress | |
| Activation of CaMK IV | |
| Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon | |
| Activation of NIMA Kinases NEK9, NEK6, NEK7 | |
| Activation of PKB | |
| Activation of PPARGC1A (PGC-1alpha) by phosphorylation | |
| Activation of Rac | |
| AMPK inhibits chREBP transcriptional activation activity | |
| Antigen activates B Cell Receptor (BCR) leading to generation of second messenge | |
| APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins | |
| Apoptotic cleavage of cellular proteins | |
| Apoptotic execution phase | |
| ARMS-mediated activation | |
| Ca2+ pathway | |
| CaMK IV-mediated phosphorylation of CREB | |
| Caspase-8 activation by cleavage | |
| CD28 co-stimulation | |
| CD28 dependent PI3K/Akt signaling | |
| CD28 dependent Vav1 pathway | |
| CDO in myogenesis | |
| Cell surface interactions at the vascular wall | |
| Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | |
| Circadian Clock | |
| Condensation of Prometaphase Chromosomes | |
| Constitutive PI3K/AKT Signaling in Cancer | |
| CREB phosphorylation | |
| CREB phosphorylation through the activation of CaMKII | |
| CREB phosphorylation through the activation of CaMKK | |
| CREB phosphorylation through the activation of Ras | |
| CRMPs in Sema3A signaling | |
| CTLA4 inhibitory signaling | |
| Cyclin A/B1 associated events during G2/M transition | |
| Cyclin A:Cdk2-associated events at S phase entry | |
| Cyclin D associated events in G1 | |
| Cyclin E associated events during G1/S transition | |
| DAP12 signaling | |
| DCC mediated attractive signaling | |
| Dimerization of procaspase-8 | |
| disassembly of the destruction complex and recruitment of AXIN to the membrane | |
| Downstream signal transduction | |
| Downstream TCR signaling | |
| Dual incision reaction in GG-NER | |
| Dual incision reaction in TC-NER | |
| ECM proteoglycans | |
| Effects of PIP2 hydrolysis | |
| EGFR downregulation | |
| EGFR interacts with phospholipase C-gamma | |
| EGFR Transactivation by Gastrin | |
| EPH-ephrin mediated repulsion of cells | |
| EPH-Ephrin signaling | |
| EPHA-mediated growth cone collapse | |
| EPHB-mediated forward signaling | |
| Ephrin signaling | |
| ERK/MAPK targets | |
| ERK1 activation | |
| ERK2 activation | |
| Factors involved in megakaryocyte development and platelet production | |
| Fc epsilon receptor (FCERI) signaling | |
| FCERI mediated Ca+2 mobilization | |
| FCERI mediated MAPK activation | |
| FCERI mediated NF-kB activation | |
| FCGR activation | |
| Formation of HIV elongation complex in the absence of HIV Tat | |
| Formation of HIV-1 elongation complex containing HIV-1 Tat | |
| Formation of incision complex in GG-NER | |
| Formation of RNA Pol II elongation complex | |
| Formation of the Early Elongation Complex | |
| Formation of the HIV-1 Early Elongation Complex | |
| Formation of transcription-coupled NER (TC-NER) repair complex | |
| Frs2-mediated activation | |
| G alpha (z) signalling events | |
| G beta:gamma signalling through PI3Kgamma | |
| G2/M DNA damage checkpoint | |
| G2/M DNA replication checkpoint | |
| GAB1 signalosome | |
| Gastrin-CREB signalling pathway via PKC and MAPK | |
| Generation of second messenger molecules | |
| Glycogen breakdown (glycogenolysis) | |
| Golgi Associated Vesicle Biogenesis | |
| GPVI-mediated activation cascade | |
| GRB2 events in EGFR signaling | |
| GRB2 events in ERBB2 signaling | |
| GRB2:SOS provides linkage to MAPK signaling for Integrins | |
| Growth hormone receptor signaling | |
| HIV Transcription Initiation | |
| HSF1-dependent transactivation | |
| IKK complex recruitment mediated by RIP1 | |
| Import of palmitoyl-CoA into the mitochondrial matrix | |
| Inactivation, recovery and regulation of the phototransduction cascade | |
| Inhibition of PKR | |
| Insulin receptor recycling | |
| Integrin alphaIIb beta3 signaling | |
| Integrin cell surface interactions | |
| Interferon alpha/beta signaling | |
| Interferon gamma signaling | |
| Interleukin receptor SHC signaling | |
| Interleukin-1 signaling | |
| Interleukin-2 signaling | |
| Interleukin-3, 5 and GM-CSF signaling | |
| Interleukin-6 signaling | |
| Interleukin-7 signaling | |
| IRS activation | |
| ISG15 antiviral mechanism | |
| JNK (c-Jun kinases) phosphorylation and activation mediated by activated human | |
| Loss of Nlp from mitotic centrosomes | |
| Loss of proteins required for interphase microtubule organization from the ce | |
| MEK activation | |
| Mitotic Prometaphase | |
| mRNA Capping | |
| MyD88:Mal cascade initiated on plasma membrane | |
| NCAM signaling for neurite out-growth | |
| Nef and signal transduction | |
| Nef Mediated CD4 Down-regulation | |
| Negative regulators of RIG-I/MDA5 signaling | |
| Nephrin interactions | |
| Netrin mediated repulsion signals | |
| Netrin-1 signaling | |
| Neurophilin interactions with VEGF and VEGFR | |
| NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 | |
| NGF-independant TRKA activation | |
| NOD1/2 Signaling Pathway | |
| NoRC negatively regulates rRNA expression | |
| Nuclear Pore Complex (NPC) Disassembly | |
| Oxidative Stress Induced Senescence | |
| p130Cas linkage to MAPK signaling for integrins | |
| PD-1 signaling | |
| PECAM1 interactions | |
| Phosphorylation of CD3 and TCR zeta chains | |
| PI3K events in ERBB2 signaling | |
| PI3K/AKT activation | |
| PIP3 activates AKT signaling | |
| Platelet Adhesion to exposed collagen | |
| Platelet sensitization by LDL | |
| PLC-gamma1 signalling | |
| PLCG1 events in ERBB2 signaling | |
| Polo-like kinase mediated events | |
| Prolactin receptor signaling | |
| RAF phosphorylates MEK | |
| Ras activation uopn Ca2+ infux through NMDA receptor | |
| Recruitment of mitotic centrosome proteins and complexes | |
| Recycling pathway of L1 | |
| Regulation by c-FLIP | |
| Regulation of actin dynamics for phagocytic cup formation | |
| Regulation of AMPK activity via LKB1 | |
| Regulation of IFNA signaling | |
| Regulation of IFNG signaling | |
| Regulation of KIT signaling | |
| Regulation of PLK1 Activity at G2/M Transition | |
| Regulation of Rheb GTPase activity by AMPK | |
| Regulation of signaling by CBL | |
| Resolution of Sister Chromatid Cohesion | |
| Retrograde neurotrophin signalling | |
| RIP-mediated NFkB activation via ZBP1 | |
| RMTs methylate histone arginines | |
| RNA Pol II CTD phosphorylation and interaction with CE | |
| RNA Polymerase I Chain Elongation | |
| RNA Polymerase I Promoter Escape | |
| RNA Polymerase I Transcription Initiation | |
| RNA Polymerase I Transcription Termination | |
| RNA Polymerase II HIV Promoter Escape | |
| RNA Polymerase II Pre-transcription Events | |
| RNA Polymerase II Promoter Escape | |
| RNA Polymerase II Transcription Elongation | |
| RNA Polymerase II Transcription Initiation | |
| RNA Polymerase II Transcription Initiation And Promoter Clearance | |
| RNA Polymerase II Transcription Pre-Initiation And Promoter Opening | |
| Role of Abl in Robo-Slit signaling | |
| Role of DCC in regulating apoptosis | |
| Role of LAT2/NTAL/LAB on calcium mobilization | |
| RSK activation | |
| Sema3A PAK dependent Axon repulsion | |
| SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion | |
| Senescence-Associated Secretory Phenotype (SASP) | |
| Separation of Sister Chromatids | |
| SHC activation | |
| SHC1 events in EGFR signaling | |
| SHC1 events in ERBB2 signaling | |
| Signal attenuation | |
| Signal regulatory protein (SIRP) family interactions | |
| Signal transduction by L1 | |
| Signaling by activated point mutants of FGFR1 | |
| Signaling by activated point mutants of FGFR3 | |
| Signaling by BMP | |
| Signaling by constitutively active EGFR | |
| Signaling by EGFR | |
| Signaling by ERBB2 | |
| Signaling by ERBB4 | |
| Signaling by FGFR | |
| Signaling by FGFR mutants | |
| Signaling by FGFR2 amplification mutants | |
| Signaling by FGFR3 mutants | |
| Signaling by Hippo | |
| Signaling by Insulin receptor | |
| Signaling by Leptin | |
| Signaling by PDGF | |
| Signaling by SCF-KIT | |
| Signalling to p38 via RIT and RIN | |
| Signalling to RAS | |
| Signalling to STAT3 | |
| Smooth Muscle Contraction | |
| Sphingolipid de novo biosynthesis | |
| Synthesis of PIPs at the plasma membrane | |
| t(4;14) translocations of FGFR3 | |
| Tat-mediated elongation of the HIV-1 transcript | |
| TNF signaling | |
| TRAF3-dependent IRF activation pathway | |
| TRAF6 mediated IRF7 activation | |
| Trafficking of AMPA receptors | |
| Transcription of the HIV genome | |
| Transcriptional activation of mitochondrial biogenesis | |
| Translocation of GLUT4 to the plasma membrane | |
| Translocation of ZAP-70 to Immunological synapse | |
| TRIF-mediated programmed cell death | |
| TRKA activation by NGF | |
| TRP channels | |
| Ubiquitin Mediated Degradation of Phosphorylated Cdc25A | |
| Unblocking of NMDA receptor, glutamate binding and activation | |
| Uptake and function of anthrax toxins | |
| VEGF binds to VEGFR leading to receptor dimerization | |
| VEGFA-VEGFR2 Pathway | |
| VEGFR2 mediated cell proliferation | |
| VEGFR2 mediated vascular permeability | |
| WNT mediated activation of DVL |
