| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| November 10th, 2008 | 25 | Yes |
Popular Name: Felodipine Felodipine
Find On: PubMed — Wikipedia — Google
CAS Numbers: 72509-76-3 , 72509-76-3; 86189-69-7 , 86189-69-7 , [72509-76-3]
(+-)-Ethyl methyl 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate
(+/-) ethyl methyl 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-4-(2,3-dichlorophenyl)-2,6-dimethyl-, ethyl methyl ester
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-4-(2,3-dichlorophenyl)-2,6-dimethyl-,ethyl methyl ester
3,5-Pyridinedicarboxylic acid, 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-, ethyl methyl ester
3-ethyl 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate
3-ethyl 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
4-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinecarboxylic acid ethyl methyl ester
4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid ethyl methyl ester
5-O-ethyl 3-O-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
72509-76-3; CPD001496951; Felodipine; SAM002589971
72509-76-3; D00319; Felodipine (JAN/USP/INN); Plendil (TN)
72509-76-3; Felodipine; Prestwick_797
Alphapharm Brand of Felodipine
AstraZeneca Brand of Felodipine
CPD001496951; Felodipine; SAM002589971
ct Arzneimittel Brand of Felodipine
ct-Arzneimittel Brand of Felodipine
Dl-Felodipine;Felodipina [INN-Spanish];Felodipine [Usan:Ban:Inn];Felodipinum [INN-Latin]
ethyl methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
Merck dura Brand of Felodipine
Pharmaceutica Astra Brand of Felodipine
Pharmacia Spain Brand of Felodipine
Plendil, Renedil, Feloday, Felodipine
ratiopharm Brand of Felodipine
Stadapharm Brand of Felodipine
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 4.05 | 9.51 | -34.69 | 0 | 5 | -1 | 71 | 383.251 | 5 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| ALOGPS_SOLUBILITY | 7.15e-03 g/l | DrugBank-approved |
| purity | 9.500000000000000e+001 | Enamine Building Blocks Enamine Building Blocks |
| Purity | 99% | APIChem |
| Purity | >99% | Fluorochem |
| Indications | Antihypertensive | KeyOrganics Bioactives |
| PUBCHEM_SUBSTANCE_COMMENT | NCC_SAMPLE_SUPPLIER : LightBiologicals; NCC_SUPPLIER_STRUCTURE_ID : F-7796; NCC_SUPPLIER_SAMPLE_COMMENTS : YELLOWISH CRYSTALLINE POWDER | NIH Clinical Collection via PubChem |
| Target | NULL | Selleck Chemicals |
| PUBCHEM_SUBSTANCE_COMMENT | SAMPLE_SUPPLIER: LightBiologicals; SUPPLIER_STRUCTURE_ID: F-7796; SUPPLIER_COMMENTS: YELLOWISH CRYSTALLINE POWDER | NIH Clinical Collection via PubChem |
| Therapy | vasodilator, Ca channel blocker | SMDC Iconix |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| Z50425-3-O | Plasmodium Falciparum (cluster #3 Of 22), Other | Other | 7943 | 0.29 | Functional ≤ 10μM |
| Z50512-1-O | Cavia Porcellus (cluster #1 Of 7), Other | Other | 1 | 0.50 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| Z50512 | Z50512 | Cavia Porcellus | 1.45 | 0.49 | Functional ≤ 10μM |
| Z50425 | Z50425 | Plasmodium Falciparum | 7943.28235 | 0.29 | Functional ≤ 10μM |
