UCSF

ZINC19862631

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.31 5.85 -46.72 2 5 -1 100 359.386 2

Vendor Notes

Note Type Comments Provided By
Target AMPK Selleck Chemicals

Activity (Go SEA)

Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
AAPK1-1-E AMP-activated Protein Kinase, Alpha-1 Subunit (cluster #1 Of 1), Eukaryotic Eukaryotes 116 0.37 Binding ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
AAPK1_RAT P54645 AMP-activated Protein Kinase, Alpha-1 Subunit, Rat 116 0.37 Binding ≤ 1μM
AAPK1_RAT P54645 AMP-activated Protein Kinase, Alpha-1 Subunit, Rat 116 0.37 Binding ≤ 10μM

Reactome Annotations from Targets (via Uniprot)

Description Species
Regulation of AMPK activity via LKB1
Regulation of Rheb GTPase activity by AMPK

Analogs ( Draw Identity 99% 90% 80% 70% )

No pre-computed analogs available. Try a structural similarity search.