| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| November 27th, 2008 | 21 | Yes |
Popular Name: benzylBLAHamine benzylBLAHamine
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.31 | 6.33 | -10.54 | 2 | 4 | 0 | 55 | 296.399 | 2 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| LIMK1-1-E | LIM Domain Kinase 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 660 | 0.41 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| LIMK1_HUMAN | P53667 | LIM Domain Kinase 1, Human | 660 | 0.41 | Binding ≤ 1μM |
| LIMK1_HUMAN | P53667 | LIM Domain Kinase 1, Human | 660 | 0.41 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| EPHB-mediated forward signaling | |
| Regulation of actin dynamics for phagocytic cup formation | |
| Sema3A PAK dependent Axon repulsion | |
| Sema4D induced cell migration and growth-cone collapse |
