UCSF

ZINC24708103

Draw Identity 99% 90% 80% 70%

Substance Information

In ZINC since Heavy atoms Benign functionality
January 20th, 2009 40 No

Popular Name: Oxidized glutathione Oxidized glutathione

Find On: PubMed — Wikipedia — Google

CAS Numbers: 103239-24-3; 27025-41-8(acid) , 27025-41-8

Other Names:

(2S)-2-azaniumyl-4-{[(1R)-2-{[(2R)-2-[(4S)-4-azaniumyl-4-carboxylatobutanamido]-2-[(carboxylatomethyl)carbamoyl]ethyl]disulfanyl}-1-[(carboxylatomethyl)carbamoyl]ethyl]carbamoyl}butanoate;Glutathione disulfide;GSSG;L(-)-Glutathione(oxidized);Oxiglutatione

2-amino-4-[(2-{[2-(4-amino-4-carboxybutanamido)-2-(carboxymethylcarbamoyl)ethyl]disulfanyl}-1-(carboxymethylcarbamoyl)ethyl)carbamoyl]butanoic acid

27025-41-8; C00127; GSSG; Glutathione disulfide; Oxidized glutathione; Oxiglutatione

27025-41-8; D00031; Glutathione (TN); Oxiglutatione (JAN/INN)

27025-41-8; GSH; GSSG; OXIDIZED-GLUTATHIONE; glutathione; glutathione disulfide; glutathione ox; glutathione oxidized; oxidized glutathione

Bi(glutathion-S-yl); Bis(gamma-glutamyl-L-cysteinylglycine) disulfide; CCRIS 780; EINECS 248-170-7; GSSG; Glutamine, N,N'-(dithiobis(1-((carboxymethyl)carbamoyl)ethylene))di-, L-; Glutathione disulfide; Glutathione disulphide; Glutathione, oxidized; Gluta

Bi(glutathion-S-yl); Bis(gamma-glutamyl-L-cysteinylglycine) disulfide; GSSG; Glutamine, N,N'-(dithiobis(1-((carboxymethyl)carbamoyl)ethylene))di-, L-; Glutathione disulfide; Glutathione disulphide; Glutathione, oxidized; Glutathione-ssg; Glutathone disulf

CALCIUM CHLORIDE; DEXTROSE; ENDOSOL EXTRA; GLUTATHIONE DISULFIDE; LS-187876; MAGNESIUM CHLORIDE; POTASSIUM CHLORIDE; SODIUM BICARBONATE; SODIUM CHLORIDE; SODIUM PHOSPHATE

CHEBI:7840; CHEBI:42832; CHEBI:14720; CHEBI:14328; CHEBI:24336

DNC001072

FDA)

glutathione disulfide

Glutathione disulfide (FDA); Oxiglutatione (FDA

Glutathione Disulfide (FDA); Oxiglutatione (INN

glutathione disulfide(2-)

glutathione disulfide; glutathione disulfide dianion

glutathione disulphide

Glutathione oxidized form

glutathione; Glutathione disulfide; glutathione disulphide; glutathione ox; glutathione oxidized; GSH; GSSG; l-glutathione oxidized; L(-)-Glutathione(oxidized); oxidised glutathione; Oxidized glutathione; OXIDIZED GLUTATHIONE DISULFIDE; OXIDIZED-GLUTATHIO

GSSG; Glutathione disulfide; L(-)-Glutathione(oxidized); Oxiglutatione; (2S)-2-azaniumyl-4-{[(1R)-2-{[(2R)-2-[(4S)-4-azaniumyl-4-carboxylatobutanamido]-2-[(carboxylatomethyl)carbamoyl]ethyl]disulfanyl}-1-[(carboxylatomethyl)carbamoyl]ethyl]carbamoyl}butan

GSSG;Glutathione disulfide;L(-)-Glutathione(oxidized);Oxiglutatione;(2S)-2-azaniumyl-4-{[(1R)-2-{[(2R)-2-[(4S)-4-azaniumyl-4-carboxylatobutanamido]-2-[(carboxylatomethyl)carbamoyl]ethyl]disulfanyl}-1-[(carboxylatomethyl)carbamoyl]ethyl]carbamoyl}butanoate

INN)

L(-)-Glutathione, oxidized, 98%

MFCD00063106

Oxiglutatione

OXIGLUTATIONE DISODIUM SALT

Download: MOL2 SDF SMILES Flexibase

Annotations

Vendors

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -6.11 1.52 -194.56 9 18 -3 331 609.616 21 ↓
Hi High (pH 8-9.5) -6.11 1.2 -232.76 8 18 -4 329 608.608 21 ↓
Hi High (pH 8-9.5) -6.01 -9.52 -285.39 8 18 -4 343 608.608 21 ↓
Mid Mid (pH 6-8) -6.11 1.81 -167.02 10 18 -2 332 610.624 21 ↓

Vendor Notes

Note Type Comments Provided By
Mp [°C] 178 Acros Organics
UniProt Database Links AB1C_ARATH; AB2C_ARATH; AB5C_ARATH; APR1_ARATH; APR1_ORYSJ; APR2_ARATH; APR3_ARATH; CDR_STAA8; DHAR1_ARATH; DHAR2_ARATH; DHAR3_ARATH; ETHE1_HUMAN; G3PC1_ARATH; G3PC2_ARATH; GAGT1_ARATH; GASHR_MARGR; GLRX1_BOVIN; GLRX1_CHICK; GLRX1_HUMAN; GLRX1_MOUSE; GLRX ChEBI
therap antioxidant MicroSource World Drugs
UniProt Database Links APR1_ARATH; APR1_ORYSJ; APR2_ARATH; APR3_ARATH; GASHR_MARGR; GLRX1_BOVIN; GLRX1_CHICK; GLRX1_HUMAN; GLRX1_MOUSE; GLRX1_PIG; GLRX1_RABIT; GLRX1_RAT; GLRX1_RICBR; GLRX1_RICCN; GLRX1_RICFE; GLRX1_RICPR; GLRX1_RICTY; GLRX1_SYNY3; GLRX2_SYNY3; GLRX_DICDI; GLRX ChEBI
PUBCHEM_PATENT_ID EP1033124A1 IBM Patent Data
H phrase H335: May cause respiratory irritation Acros Organics
P phrase P301 + P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician Acros Organics
R phrase R36/37/38: Irritating to eyes, respiratory system and skin. Acros Organics
Reactome Database Links REACT_11095; REACT_1461; REACT_150133; REACT_150230; REACT_150334; REACT_150391; REACT_172582; REACT_172584; REACT_172585; REACT_172730; REACT_172757; REACT_2037; REACT_2220 ChEBI
S phrase S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Acros Organics
Patent Database Links US2007218549; US2007243262 ChEBI
Hazard XI: Irritant Acros Organics

Activity (Go SEA)

Direct Reactome Annotations (via ChEBI)

Description Species
Detoxification of Reactive Oxygen Species
Purine catabolism
Sulfide oxidation to sulfate
Synthesis and interconversion of nucleotide di- and triphosphates
Synthesis of 12-eicosatetraenoic acid derivatives
Synthesis of 15-eicosatetraenoic acid derivatives
Synthesis of 5-eicosatetraenoic acids
Vitamin C (ascorbate) metabolism

Analogs ( Draw Identity 99% 90% 80% 70% )

No pre-computed analogs available. Try a structural similarity search.