| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 27th, 2004 | 24 | No |
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.63 | 6.85 | -14.93 | 2 | 5 | 0 | 91 | 321.332 | 6 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| LOX5-4-E | Arachidonate 5-lipoxygenase (cluster #4 Of 6), Eukaryotic | Eukaryotes | 1890 | 0.33 | Binding ≤ 10μM |
| LX12L-1-E | Arachidonate 12-lipoxygenase (cluster #1 Of 1), Eukaryotic | Eukaryotes | 63 | 0.42 | Binding ≤ 10μM |
| LX15B-1-E | Arachidonate 15-lipoxygenase, Type II (cluster #1 Of 1), Eukaryotic | Eukaryotes | 3330 | 0.32 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| LX12L_RAT | Q02759 | Arachidonate 12-lipoxygenase, Rat | 63 | 0.42 | Binding ≤ 1μM |
| LX12L_RAT | Q02759 | Arachidonate 12-lipoxygenase, Rat | 63 | 0.42 | Binding ≤ 10μM |
| LX15B_RAT | Q8K4F2 | Arachidonate 15-lipoxygenase, Type II, Rat | 3330 | 0.32 | Binding ≤ 10μM |
| LOX5_RAT | P12527 | Arachidonate 5-lipoxygenase, Rat | 1890 | 0.33 | Binding ≤ 10μM |
