| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| February 1st, 2009 | 32 | No |
Popular Name: Phorbol 12,13-diacetate Phorbol 12,13-diacetate
Find On: PubMed — Wikipedia — Google
CAS Number: 24928-15-2
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 1.93 | 4.6 | -14.51 | 3 | 8 | 0 | 130 | 448.512 | 5 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| KPCD-2-E | Protein Kinase C Delta (cluster #2 Of 4), Eukaryotic | Eukaryotes | 7 | 0.36 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| KPCD_MOUSE | P28867 | Protein Kinase C Delta, Mouse | 0.351 | 0.41 | Binding ≤ 1μM |
| KPCD_MOUSE | P28867 | Protein Kinase C Delta, Mouse | 0.351 | 0.41 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Apoptotic cleavage of cellular proteins | |
| Calmodulin induced events | |
| DAG and IP3 signaling | |
| Effects of PIP2 hydrolysis | |
| G alpha (z) signalling events | |
| HuR stabilizes mRNA | |
| Interferon gamma signaling | |
| Role of phospholipids in phagocytosis | |
| VEGFR2 mediated cell proliferation |
