| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| February 3rd, 2009 | 18 | Yes |
Popular Name: 1H-Indazole-4-carboxamide, 2,3-dihydro-3-oxo-N-pentyl- 1H-Indazole-4-carboxamide, 2,3-d…
Find On: PubMed — Wikipedia — Google
CAS Number: 128484-42-4
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.62 | 1.65 | -13.32 | 3 | 5 | 0 | 78 | 247.298 | 5 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| LOX5-4-E | Arachidonate 5-lipoxygenase (cluster #4 Of 7), Eukaryotic | Eukaryotes | 300 | 0.51 | Functional ≤ 10μM |
| Z50588-4-O | Canis Familiaris (cluster #4 Of 7), Other | Other | 300 | 0.51 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| LOX5_HUMAN | P09917 | Arachidonate 5-lipoxygenase, Human | 300 | 0.51 | Functional ≤ 10μM |
| Z50588 | Z50588 | Canis Familiaris | 300 | 0.51 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Synthesis of 5-eicosatetraenoic acids | |
| Synthesis of Leukotrienes (LT) and Eoxins (EX) | |
| Synthesis of Lipoxins (LX) |
No pre-computed analogs available. Try a structural similarity search.