| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| November 1st, 2004 | 23 | Yes |
Popular Name: N-[5-(1-ethylpropyl)-1,3,4-thiadiazol-2-yl]-2,3-dihydro-1,4-benzodioxine-6-carboxamide N-[5-(1-ethylpropyl)-1,3,4-thiad…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.51 | -0.39 | -17.57 | 1 | 6 | 0 | 73 | 333.413 | 5 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PE2R3-1-E | Prostanoid EP3 Receptor (cluster #1 Of 3), Eukaryotic | Eukaryotes | 100 | 0.43 | Binding ≤ 10μM |
| PE2R3-1-E | Prostanoid EP3 Receptor (cluster #1 Of 2), Eukaryotic | Eukaryotes | 79 | 0.43 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PE2R3_HUMAN | P43115 | Prostanoid EP3 Receptor, Human | 100 | 0.43 | Binding ≤ 1μM |
| PE2R3_HUMAN | P43115 | Prostanoid EP3 Receptor, Human | 100 | 0.43 | Binding ≤ 10μM |
| PE2R3_HUMAN | P43115 | Prostanoid EP3 Receptor, Human | 79.4328235 | 0.43 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (i) signalling events | |
| Prostanoid ligand receptors |
