| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| February 14th, 2009 | 36 | No |
None
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 1.35 | -1.32 | -60.64 | 3 | 12 | -1 | 186 | 530.564 | 7 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| TPOR-1-E | Thrombopoietin Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 10000 | 0.19 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| TPOR_HUMAN | P40238 | Thrombopoietin Receptor, Human | 10000 | 0.19 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Platelet Aggregation (Plug Formation) |
