| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| February 25th, 2009 | 12 | No |
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 0.82 | 1.4 | -45.97 | 4 | 2 | 1 | 48 | 184.284 | 3 | ↓ |
| Hi High (pH 8-9.5) | 0.82 | 1.08 | -6.03 | 3 | 2 | 0 | 46 | 183.276 | 3 | ↓ |
| Hi High (pH 8-9.5) | 0.82 | 1.86 | -37 | 4 | 2 | 0 | 48 | 183.276 | 3 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| AMPN-2-E | Aminopeptidase N (cluster #2 Of 5), Eukaryotic | Eukaryotes | 45 | 0.86 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| AMPN_HUMAN | P15144 | Aminopeptidase N, Human | 45 | 0.86 | Binding ≤ 1μM |
| AMPN_HUMAN | P15144 | Aminopeptidase N, Human | 45 | 0.86 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Metabolism of Angiotensinogen to Angiotensins |
