Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.91	9.27	-61.92	3	5	1	60	434.535	5	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	2.91	6.95	-15.13	2	5	0	59	433.527	5	↓ MOL2 SDF SMILES Flexibase

Clustered Target Annotations
Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
5HT1D-1-E	Serotonin 1d (5-HT1d) Receptor (cluster #1 Of 2), Eukaryotic	Eukaryotes	10	0.35	Binding ≤ 10μM
SC6A4-1-E	Serotonin Transporter (cluster #1 Of 4), Eukaryotic	Eukaryotes	8	0.35	Binding ≤ 10μM
Z104304-1-O	Adrenergic Receptor Alpha-1 (cluster #1 Of 3), Other	Other	96	0.31	Binding ≤ 10μM
DRD2-4-E	Dopamine D2 Receptor (cluster #4 Of 24), Eukaryotic	Eukaryotes	704	0.27	Binding ≤ 10μM

ChEMBL Target Annotations
Uniprot	Swissprot	Description	Affinity (nM)	LE (kcal/mol/atom)	Type
Z104304	Z104304	Adrenergic Receptor Alpha-1	96	0.31	Binding ≤ 1μM
DRD2_RAT	P61169	Dopamine D2 Receptor, Rat	704	0.27	Binding ≤ 1μM
5HT1D_HUMAN	P28221	Serotonin 1d (5-HT1d) Receptor, Human	10	0.35	Binding ≤ 1μM
SC6A4_HUMAN	P31645	Serotonin Transporter, Human	8.1	0.35	Binding ≤ 1μM
Z104304	Z104304	Adrenergic Receptor Alpha-1	96	0.31	Binding ≤ 10μM
DRD2_RAT	P61169	Dopamine D2 Receptor, Rat	704	0.27	Binding ≤ 10μM
5HT1D_HUMAN	P28221	Serotonin 1d (5-HT1d) Receptor, Human	10	0.35	Binding ≤ 10μM
SC6A4_HUMAN	P31645	Serotonin Transporter, Human	8.1	0.35	Binding ≤ 10μM

Description	Species
Dopamine receptors	Rattus norvegicus (DRD2_RAT)
G alpha (i) signalling events	Homo sapiens (5HT1D_HUMAN) Rattus norvegicus (DRD2_RAT)
Serotonin receptors	Homo sapiens (5HT1D_HUMAN)