In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
March 14th, 2009 | 47 | No |
None
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 7.11 | 20.7 | -91.68 | 4 | 7 | 2 | 76 | 642.929 | 17 | ↓ |
Hi High (pH 8-9.5) | 7.11 | 18.49 | -54.67 | 3 | 7 | 1 | 75 | 641.921 | 17 | ↓ |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
CAC1B-1-E | Voltage-gated N-type Calcium Channel Alpha-1B Subunit (cluster #1 Of 1), Eukaryotic | Eukaryotes | 880 | 0.18 | Functional ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
CAC1B_HUMAN | Q00975 | Voltage-gated N-type Calcium Channel Alpha-1B Subunit, Human | 880 | 0.18 | Functional ≤ 10μM |
Description | Species |
---|---|
Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Chann |