| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| July 23rd, 2004 | 20 | Yes |
Popular Name: (4-aminophenyl)-[4-(4-chlorophenyl)thiazol-2-yl]amine (4-aminophenyl)-[4-(4-chlorophen…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 4.41 | -2.29 | -6.66 | 3 | 3 | 0 | 50 | 301.802 | 3 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| TERA-1-E | Transitional Endoplasmic Reticulum ATPase (cluster #1 Of 1), Eukaryotic | Eukaryotes | 80 | 0.50 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| TERA_HUMAN | P55072 | Transitional Endoplasmic Reticulum ATPase, Human | 80 | 0.50 | Binding ≤ 1μM |
| TERA_HUMAN | P55072 | Transitional Endoplasmic Reticulum ATPase, Human | 80 | 0.50 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Hedgehog ligand biogenesis | |
| Hh ligand biogenesis disease | |
| HSF1 activation |
