In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
October 2nd, 2009 | 36 | Yes |
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 4.83 | 12.36 | -12.41 | 2 | 6 | 0 | 74 | 486.66 | 10 | ↓ |
Lo Low (pH 4.5-6) | 4.83 | 12.78 | -47.15 | 3 | 6 | 1 | 76 | 487.668 | 10 | ↓ |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
KCNA5-1-E | Voltage-gated Potassium Channel Subunit Kv1.5 (cluster #1 Of 3), Eukaryotic | Eukaryotes | 490 | 0.25 | Binding ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
KCNA5_HUMAN | P22460 | Voltage-gated Potassium Channel Subunit Kv1.5, Human | 490 | 0.25 | Binding ≤ 1μM |
KCNA5_HUMAN | P22460 | Voltage-gated Potassium Channel Subunit Kv1.5, Human | 490 | 0.25 | Binding ≤ 10μM |
Description | Species |
---|---|
Voltage gated Potassium channels |