| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 3rd, 2009 | 21 | No |
Popular Name: 5-chloro-2-hydroxy-N-(4-hydroxy-2-nitro-phenyl)benzamide 5-chloro-2-hydroxy-N-(4-hydroxy-…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.38 | 3.6 | -9.41 | 3 | 7 | 0 | 115 | 308.677 | 3 | ↓ |
| Hi High (pH 8-9.5) | 3.38 | 4.61 | -45.64 | 2 | 7 | -1 | 118 | 307.669 | 3 | ↓ |
| Hi High (pH 8-9.5) | 3.38 | 4.37 | -40.82 | 2 | 7 | -1 | 118 | 307.669 | 3 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| KCMA1-1-E | Calcium-activated Potassium Channel Subunit Alpha-1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 5248 | 0.35 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| KCMA1_HUMAN | Q12791 | Large Conductance Calcium-activated Potassium Channel Subfamily M Alpha Member 1 Isoform B, Human | 5248.0746 | 0.35 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Ca2+ activated K+ channels | |
| cGMP effects |
