Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	4.64	17.15	-66.09	1	6	1	66	531.467	5	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.64	16.5	-20.63	0	6	0	65	530.459	5	↓ MOL2 SDF SMILES Flexibase

Clustered Target Annotations
Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
FNTA-1-E	Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit (cluster #1 Of 3), Eukaryotic	Eukaryotes	20	0.29	Binding ≤ 10μM
FNTB-1-E	Protein Farnesyltransferase Beta Subunit (cluster #1 Of 3), Eukaryotic	Eukaryotes	20	0.29	Binding ≤ 10μM
PGTB1-1-E	Geranylgeranyl Transferase Type I Beta Subunit (cluster #1 Of 2), Eukaryotic	Eukaryotes	1500	0.22	Binding ≤ 10μM

ChEMBL Target Annotations
Uniprot	Swissprot	Description	Affinity (nM)	LE (kcal/mol/atom)	Type
FNTB_HUMAN	P49356	Protein Farnesyltransferase Beta Subunit, Human	20	0.29	Binding ≤ 1μM
FNTA_HUMAN	P49354	Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Human	20	0.29	Binding ≤ 1μM
PGTB1_HUMAN	P53609	Geranylgeranyl Transferase Type I Beta Subunit, Human	1500	0.22	Binding ≤ 10μM
FNTB_HUMAN	P49356	Protein Farnesyltransferase Beta Subunit, Human	20	0.29	Binding ≤ 10μM
FNTA_HUMAN	P49354	Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Human	1500	0.22	Binding ≤ 10μM

Description	Species
Apoptotic cleavage of cellular proteins	Homo sapiens (FNTA_HUMAN)
Inactivation, recovery and regulation of the phototransduction cascade	Homo sapiens (FNTA_HUMAN)