| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| September 30th, 2005 | 25 | Yes |
Popular Name: Prostaglandin E1 Prostaglandin E1
Find On: PubMed — Wikipedia — Google
CAS Numbers: 20897-91-0 , 745-65-3
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.36 | -2.65 | -51.46 | 2 | 5 | -1 | 97 | 353.479 | 13 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PE2R1-2-E | Prostanoid EP1 Receptor (cluster #2 Of 2), Eukaryotic | Eukaryotes | 100 | 0.39 | Binding ≤ 10μM |
| PE2R2-2-E | Prostanoid EP2 Receptor (cluster #2 Of 2), Eukaryotic | Eukaryotes | 87 | 0.40 | Binding ≤ 10μM |
| PE2R3-2-E | Prostanoid EP3 Receptor (cluster #2 Of 3), Eukaryotic | Eukaryotes | 5 | 0.46 | Binding ≤ 10μM |
| PE2R4-2-E | Prostanoid EP4 Receptor (cluster #2 Of 2), Eukaryotic | Eukaryotes | 3 | 0.48 | Binding ≤ 10μM |
| PI2R-2-E | Prostanoid IP Receptor (cluster #2 Of 2), Eukaryotic | Eukaryotes | 150 | 0.38 | Binding ≤ 10μM |
| PE2R2-1-E | Prostanoid EP2 Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 3 | 0.48 | Functional ≤ 10μM |
| PI2R-1-E | Prostanoid IP Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 2 | 0.49 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PE2R1_MOUSE | P35375 | Prostanoid EP1 Receptor, Mouse | 100 | 0.39 | Binding ≤ 1μM |
| PE2R2_MOUSE | Q62053 | Prostanoid EP2 Receptor, Mouse | 87 | 0.40 | Binding ≤ 1μM |
| PE2R3_MOUSE | P30557 | Prostanoid EP3 Receptor, Mouse | 5 | 0.46 | Binding ≤ 1μM |
| PE2R4_MOUSE | P32240 | Prostanoid EP4 Receptor, Mouse | 3.3 | 0.47 | Binding ≤ 1μM |
| PI2R_HUMAN | P43119 | Prostanoid IP Receptor, Human | 150 | 0.38 | Binding ≤ 1μM |
| PE2R1_MOUSE | P35375 | Prostanoid EP1 Receptor, Mouse | 100 | 0.39 | Binding ≤ 10μM |
| PE2R2_MOUSE | Q62053 | Prostanoid EP2 Receptor, Mouse | 87 | 0.40 | Binding ≤ 10μM |
| PE2R3_MOUSE | P30557 | Prostanoid EP3 Receptor, Mouse | 5 | 0.46 | Binding ≤ 10μM |
| PE2R4_MOUSE | P32240 | Prostanoid EP4 Receptor, Mouse | 3.3 | 0.47 | Binding ≤ 10μM |
| PI2R_HUMAN | P43119 | Prostanoid IP Receptor, Human | 150 | 0.38 | Binding ≤ 10μM |
| PE2R2_MOUSE | Q62053 | Prostanoid EP2 Receptor, Mouse | 2.6 | 0.48 | Functional ≤ 10μM |
| PI2R_HUMAN | P43119 | Prostanoid IP Receptor, Human | 1.8 | 0.49 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (q) signalling events | |
| G alpha (s) signalling events | |
| Prostacyclin signalling through prostacyclin receptor | |
| Prostanoid ligand receptors |
