| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 19th, 2005 | 32 | No |
Popular Name: Loteprednol etabonate Loteprednol etabonate
Find On: PubMed — Wikipedia — Google
CAS Numbers: 82034-46-6 , 82034-46-6 , [82034-46-6]
82034-46-6; D01689; Lotemax (TN); Loteprednol etabonate (JAN/USAN)
Alrex, Lotemax, Loteprednol etabonate
chloromethyl 17alpha-[(ethoxycarbonyl)oxy]-11beta-hydroxy-3-oxoandrosta-1,4-diene-17beta-carboxylate
CPD000469178; LOTEPREDNOL ETABONATE
CPD000469178; LOTEPREDNOL ETABONATE; SAM001246630
INN); Loteprednol Etabonate (FDA
Loteprednol etabonate (JAN/USAN)
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.68 | 10.8 | -17.01 | 1 | 7 | 0 | 99 | 466.958 | 7 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| biological_use | Antiinflammatory agent | IBScreen Bioactives IBScreen Bioactives |
| mechanism | Corticosteroid | IBScreen Bioactives |
| Patent Database Links | EP0795327; EP1438962; EP1764111; US2004029967; US2007259890; US2008292608; WO2005116000; WO2006084176 | ChEBI |
| Target | Glucocorticoid Receptor | Selleck Chemicals |
| PUBCHEM_SUBSTANCE_COMMENT | NCC_SAMPLE_SUPPLIER : Sequoia Research Products Ltd.; NCC_SUPPLIER_STRUCTURE_ID : SRP01583l | NIH Clinical Collection via PubChem |
| Target | Others | Selleck Chemicals |
| PUBCHEM_SUBSTANCE_COMMENT | SAMPLE_SUPPLIER: Sequoia Research Products Ltd.; SUPPLIER_STRUCTURE_ID: SRP01583l | NIH Clinical Collection via PubChem |
| biological_use | Used in ophthalmology | IBScreen Bioactives |
