| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 25th, 2005 | 34 | Yes |
Popular Name: OSU-03012 OSU-03012
Find On: PubMed — Wikipedia — Google
CAS Numbers: 742112-33-0 , [742112-33-0]
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 5.16 | -0.1 | -58.83 | 4 | 5 | 1 | 74 | 461.467 | 5 | ↓ |
| Hi High (pH 8-9.5) | 9.70 | 21.4 | -6.43 | 1 | 3 | 0 | 47 | 576.906 | 15 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| Target | PDK-1 | Selleck Chemicals |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| Z80418-1-O | RAW264.7 (Monocytic-macrophage Leukemia Cells) (cluster #1 Of 2), Other | Other | 10000 | 0.21 | ADME/T ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| Z80418 | Z80418 | RAW264.7 (Monocytic-macrophage Leukemia Cells) | 10000 | 0.21 | ADME/T ≤ 10μM |
