| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| November 7th, 2005 | 20 | No |
Popular Name: DANA DANA
Find On: PubMed — Wikipedia — Google
CAS Numbers: 209977-53-7 , 24967-27-9 , [209977-53-7] , [24967-27-9]
2,3-Dehydro-2-deoxy-N-acetylneuraminic acid
2-deoxy-2,3-dehydro-N-acetylneuraminic acid
2-Deoxy-2,3-dehydro-N-acetylneuraminic acid; 24967-27-9; C04580
N-Acetyl-2,3-dehydro-2-deoxyneuraminic acid sodium salt
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | -3.01 | -10.61 | -68.15 | 5 | 9 | -1 | 159 | 290.248 | 5 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| MP | 134 | TCI |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| A8K327-1-E | Sialidase 3 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 4000 | 0.38 | Binding ≤ 10μM |
| NEUR1-1-E | Sialidase 1 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 4000 | 0.38 | Binding ≤ 10μM |
| NEUR2-1-E | Sialidase 2 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 4000 | 0.38 | Binding ≤ 10μM |
| NEUR4-1-E | Sialidase 4 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 4000 | 0.38 | Binding ≤ 10μM |
| NRAM-1-V | Neuraminidase (cluster #1 Of 2), Viral | Viruses | 8600 | 0.35 | Binding ≤ 10μM |
| Z50523-1-O | Influenza B Virus (cluster #1 Of 1), Other | Other | 3000 | 0.39 | Binding ≤ 10μM |
| Z50652-1-O | Influenza A Virus (cluster #1 Of 1), Other | Other | 2800 | 0.39 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| Z50652 | Z50652 | Influenza A Virus | 2800 | 0.39 | Binding ≤ 10μM |
| Z50523 | Z50523 | Influenza B Virus | 3000 | 0.39 | Binding ≤ 10μM |
| NRAM_I34A1 | P03468 | Neuraminidase, I34a1 | 8600 | 0.35 | Binding ≤ 10μM |
| NEUR1_HUMAN | Q99519 | Sialidase 1, Human | 4000 | 0.38 | Binding ≤ 10μM |
| NEUR2_HUMAN | Q9Y3R4 | Sialidase 2, Human | 4000 | 0.38 | Binding ≤ 10μM |
| A8K327_HUMAN | A8K327 | Sialidase 3, Human | 4000 | 0.38 | Binding ≤ 10μM |
| NEUR4_HUMAN | Q8WWR8 | Sialidase 4, Human | 4000 | 0.38 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Assembly of Viral Components at the Budding Site | |
| Budding | |
| Entry of Influenza Virion into Host Cell via Endocytosis | |
| Fusion of the Influenza Virion to the Host Cell Endosome | |
| Glycosphingolipid metabolism | |
| Influenza Life Cycle | |
| Influenza Virus Induced Apoptosis | |
| Packaging of Eight RNA Segments | |
| Release | |
| Sialic acid metabolism | |
| Transport of HA trimer, NA tetramer and M2 tetramer from the endoplasmic reticul | |
| Uncoating of the Influenza Virion | |
| Viral mRNA Translation |
