| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| May 7th, 2010 | 29 | Yes |
None
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.57 | 8.84 | -28.01 | 1 | 7 | 0 | 84 | 408.483 | 3 | ↓ |
| Hi High (pH 8-9.5) | 3.64 | 7.12 | -70.9 | 0 | 7 | -1 | 91 | 407.475 | 3 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PE2R3-1-E | Prostanoid EP3 Receptor (cluster #1 Of 2), Eukaryotic | Eukaryotes | 794 | 0.29 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PE2R3_HUMAN | P43115 | Prostanoid EP3 Receptor, Human | 794.328235 | 0.29 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (i) signalling events | |
| Prostanoid ligand receptors |
